STRINGSTRING
argS argS AKU18417.1 AKU18417.1 serS serS AKU14799.1 AKU14799.1 AKU14927.1 AKU14927.1 AKU14934.1 AKU14934.1 rpmH rpmH AKU18573.1 AKU18573.1 rpsF rpsF rpsR rpsR rplI rplI AKU15075.1 AKU15075.1 AKU15088.1 AKU15088.1 AKU15089.1 AKU15089.1 AKU15232.1 AKU15232.1 AKU15239.1 AKU15239.1 AKU15323.1 AKU15323.1 lysS-2 lysS-2 rpmE2 rpmE2 rpsN-2 rpsN-2 rpmG rpmG rpmF rpmF cysS cysS AKU15770.1 AKU15770.1 AKU18762.1 AKU18762.1 glmU glmU rplY rplY pth pth AKU15919.1 AKU15919.1 AKU15924.1 AKU15924.1 AKU15926.1 AKU15926.1 AKU15932.1 AKU15932.1 lysS lysS glyQ glyQ greA greA AKU16102.1 AKU16102.1 AKU16105.1 AKU16105.1 trpS trpS AKU16201.1 AKU16201.1 AKU16202.1 AKU16202.1 AKU16205.1 AKU16205.1 AKU18820.1 AKU18820.1 AKU16222.1 AKU16222.1 prfB prfB smpB smpB AKU16325.1 AKU16325.1 gltX gltX ddl ddl rpmB rpmB rpmF-2 rpmF-2 rpsP rpsP AKU16394.1 AKU16394.1 rplS rplS rpsB rpsB tsf tsf frr frr proS proS infB infB rplU rplU rpmA rpmA AKU16518.1 AKU16518.1 lepA lepA AKU16627.1 AKU16627.1 AKU16636.1 AKU16636.1 AKU16666.1 AKU16666.1 infC infC rpmI rpmI rplT rplT pheS pheS pheT pheT tyrS tyrS AKU16689.1 AKU16689.1 aspS aspS alaS alaS mltG mltG efp efp AKU16724.1 AKU16724.1 def def fmt fmt lgt lgt AKU16772.1 AKU16772.1 AKU16774.1 AKU16774.1 AKU16776.1 AKU16776.1 AKU18486.1 AKU18486.1 AKU16777.1 AKU16777.1 AKU16782.1 AKU16782.1 AKU18934.1 AKU18934.1 rpsA rpsA AKU16825.1 AKU16825.1 AKU16834.1 AKU16834.1 AKU16836.1 AKU16836.1 glgC glgC thrS thrS AKU16901.1 AKU16901.1 AKU16904.1 AKU16904.1 lnt lnt AKU17034.1 AKU17034.1 murC murC murG murG AKU17214.1 AKU17214.1 murD murD mraY mraY murF murF leuS leuS rpsT rpsT AKU17269.1 AKU17269.1 AKU17289.1 AKU17289.1 rpsO rpsO uppP uppP ileS ileS AKU17364.1 AKU17364.1 valS valS AKU17402.1 AKU17402.1 murI murI gatB gatB gatA gatA gatC gatC glgE glgE AKU17518.1 AKU17518.1 prfA prfA rpmE rpmE AKU17645.1 AKU17645.1 AKU17662.1 AKU17662.1 rpsI rpsI rplM rplM AKU17736.1 AKU17736.1 AKU17738.1 AKU17738.1 rplQ rplQ rpsD rpsD rpsK rpsK rpsM rpsM rpmJ rpmJ infA infA rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ mraY-2 mraY-2 tuf tuf fusA fusA rpsG rpsG rpsL rpsL AKU17814.1 AKU17814.1 AKU17815.1 AKU17815.1 rplL rplL rplJ rplJ rplA rplA murE murE AKU14687.1 AKU14687.1 rplK rplK murB murB rpmG-2 rpmG-2 AKU18124.1 AKU18124.1 AKU19278.1 AKU19278.1 def-2 def-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
AKU18417.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (434 aa)
AKU14799.1Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family. (473 aa)
AKU14927.1Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
AKU14934.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
rpmH50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
AKU18573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (95 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (149 aa)
AKU15075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
AKU15088.1Peptide chain release factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
AKU15089.1threonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
AKU15232.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa)
AKU15239.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (713 aa)
AKU15323.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
lysS-2lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (599 aa)
rpmE250S ribosomal protein L31; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
rpsN-230S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpmG50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
rpmF50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. (58 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
AKU15770.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
AKU18762.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (498 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (220 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa)
AKU15919.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AKU15924.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AKU15926.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AKU15932.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
lysSlysine--tRNA ligase; Catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (1097 aa)
glyQglycyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (1008 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (164 aa)
AKU16102.1Acetylglucosamine-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
AKU16105.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (345 aa)
AKU16201.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AKU16202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AKU16205.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AKU18820.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AKU16222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1154 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (371 aa)
smpBSingle-stranded DNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome t [...] (160 aa)
AKU16325.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (479 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (373 aa)
rpmB50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. (64 aa)
rpmF-250S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. (64 aa)
rpsPHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (244 aa)
AKU16394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family. (80 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (120 aa)
rpsB30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (324 aa)
tsfElongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (275 aa)
frrRibosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (188 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (588 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1013 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpmA50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family. (90 aa)
AKU16518.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (614 aa)
AKU16627.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
AKU16636.1Methicillin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
AKU16666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
infCTranslation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (193 aa)
rpmI50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (131 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (364 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (840 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (420 aa)
AKU16689.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (605 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa)
mltGHypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (339 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
AKU16724.130S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (181 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa)
lgtDiacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (288 aa)
AKU16772.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
AKU16774.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
AKU16776.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
AKU18486.1UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
AKU16777.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1403 aa)
AKU16782.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1312 aa)
AKU18934.1GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
rpsA30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AKU16825.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
AKU16834.1Mur ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (740 aa)
AKU16836.1Cyanophycin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family. (958 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (416 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (663 aa)
AKU16901.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AKU16904.1histidyl-tRNA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
lntApolipoprotein acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (526 aa)
AKU17034.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (480 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (367 aa)
AKU17214.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (415 aa)
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (504 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (358 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (468 aa)
leuSleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (953 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa)
AKU17269.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
AKU17289.1tryptophanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (366 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
uppPUDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (279 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1089 aa)
AKU17364.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (878 aa)
AKU17402.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (277 aa)
gatBglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (503 aa)
gatAglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (511 aa)
gatCglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa)
glgEAlpha-1,4-glucan:maltose-1-phosphate maltosyltransferase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (673 aa)
AKU17518.1UDP-N-acetylmuramyl pentapeptide phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA. (71 aa)
AKU17645.1Integral membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AKU17662.1GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
rpsI30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (170 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (149 aa)
AKU17736.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (717 aa)
AKU17738.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
rplQ50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (202 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (135 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa)
rpmJ50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology. (37 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (163 aa)
rpmD50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (60 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (226 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (124 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (191 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (122 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (97 aa)
rpmC50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (88 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (283 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (122 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (328 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (217 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
mraY-2phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (362 aa)
tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (704 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
AKU17814.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AKU17815.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa)
rplL50S ribosomal protein L7; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (128 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (205 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (240 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (487 aa)
AKU14687.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (143 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (358 aa)
rpmG-250S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
AKU18124.1phenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (379 aa)
AKU19278.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (191 aa)
Your Current Organism:
Luteipulveratus mongoliensis
NCBI taxonomy Id: 571913
Other names: Dermacoccaceae bacterium MN07-A0370, L. mongoliensis, Luteipulveratus mongoliensis Ara et al. 2010, NBRC 105296, VTCC D9-09, strain MN07-A0370
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