node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADG91925.1 | ADG92366.1 | Arnit_0259 | Arnit_0701 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.961 |
ADG91925.1 | ADG93066.1 | Arnit_0259 | Arnit_1408 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | 0.989 |
ADG91925.1 | ADG93116.1 | Arnit_0259 | Arnit_1459 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | 0.950 |
ADG91925.1 | metE | Arnit_0259 | Arnit_0516 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.985 |
ADG92366.1 | ADG91925.1 | Arnit_0701 | Arnit_0259 | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.961 |
ADG92366.1 | ADG93066.1 | Arnit_0701 | Arnit_1408 | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | 0.839 |
ADG92366.1 | ADG93116.1 | Arnit_0701 | Arnit_1459 | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | 0.925 |
ADG92366.1 | metE | Arnit_0701 | Arnit_0516 | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.984 |
ADG93066.1 | ADG91925.1 | Arnit_1408 | Arnit_0259 | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.989 |
ADG93066.1 | ADG92366.1 | Arnit_1408 | Arnit_0701 | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.839 |
ADG93066.1 | metE | Arnit_1408 | Arnit_0516 | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.898 |
ADG93116.1 | ADG91925.1 | Arnit_1459 | Arnit_0259 | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.950 |
ADG93116.1 | ADG92366.1 | Arnit_1459 | Arnit_0701 | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.925 |
ADG93116.1 | metE | Arnit_1459 | Arnit_0516 | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.926 |
metE | ADG91925.1 | Arnit_0516 | Arnit_0259 | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.985 |
metE | ADG92366.1 | Arnit_0516 | Arnit_0701 | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tdn:Suden_1476 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q30QH8 Methionine adenosyltransferase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.984 |
metE | ADG93066.1 | Arnit_0516 | Arnit_1408 | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | KEGG: cth:Cthe_2304 hypothetical protein; SPTR: A3DHS7 Putative uncharacterized protein; PFAM: Methylenetetrahydrofolate reductase. | 0.898 |
metE | ADG93116.1 | Arnit_0516 | Arnit_1459 | 5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: bsu:BSU02410 homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: C2A2N3 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); PFAM: Homocysteine S-methyltransferase. | 0.926 |