STRINGSTRING
infB infB ACV24307.1 ACV24307.1 ACV24308.1 ACV24308.1 ACV24391.1 ACV24391.1 tbp tbp ACV24626.1 ACV24626.1 ACV24650.1 ACV24650.1 ACV24690.1 ACV24690.1 tfb tfb tfe tfe rpoH rpoH ACV25071.1 ACV25071.1 ACV25072.1 ACV25072.1 ACV25073.1 ACV25073.1 rpoA2 rpoA2 rpoP rpoP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
infBTranslation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (608 aa)
ACV24307.1PFAM: RNA polymerase Rpb6; KEGG: RNA polymerase I, II, III common subunit; K03014 DNA-directed RNA Polymerase II subunit F. (61 aa)
ACV24308.1PFAM: RNA polymerase, N/8 Kd subunit; KEGG: hypothetical protein; K03007 DNA-directed RNA Polymerase II subunit L. (72 aa)
ACV24391.1PFAM: RNA polymerase Rpb4. (107 aa)
tbpTATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (180 aa)
ACV24626.1Transcription termination factor Tfs; KEGG: RPC11; DNA-directed RNA polymerase III; TIGRFAM: transcription factor S; PFAM: DNA-directed RNA polymerase, M/15 kDa subunit; Transcription factor TFIIS; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
ACV24650.1SMART: helicase c2; Helicase-like, DEXD box c2 type; DEAD-like helicase; KEGG: sdn:Sden_1619 helicase C2. (653 aa)
ACV24690.1KEGG: hypothetical protein; K03022 DNA-directed RNA polymerase III subunit C25; TIGRFAM: DNA-directed RNA polymerase; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. (187 aa)
tfbTranscription factor TFIIB cyclin-related; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (331 aa)
tfeTranscription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (188 aa)
rpoHRNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
ACV25071.1PFAM: RNA polymerase beta subunit; RNA polymerase Rpb2 domain 2; RNA polymerase Rpb2 domain 3; KEGG: hypothetical protein LOC100252267; K03010 DNA-directed RNA polymerase II subunit B. (497 aa)
ACV25072.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (633 aa)
ACV25073.1DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (891 aa)
rpoA2DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (387 aa)
rpoPRNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (46 aa)
Your Current Organism:
Methanocaldococcus fervens
NCBI taxonomy Id: 573064
Other names: M. fervens AG86, Methanocaldococcus fervens AG86, Methanocaldococcus fervens DSM 4213, Methanocaldococcus fervens str. AG86, Methanocaldococcus fervens strain AG86
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