(90 nodes) Mixed, incl. RHO GTPase cycle, and Exocyst network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_2294051	Uncharacterized protein. (907 aa)
	MYCTH_2051419	Protein kinase domain-containing protein. (329 aa)
	MYCTH_2073197	Uncharacterized protein. (201 aa)
	MYCTH_2313989	Uncharacterized protein. (212 aa)
	MYCTH_2299840	Uncharacterized protein. (232 aa)
	MYCTH_2294147	ELMO domain-containing protein. (789 aa)
	MYCTH_2296214	Uncharacterized protein. (1663 aa)
	MYCTH_2296224	Uncharacterized protein. (923 aa)
	MYCTH_2296379	Uncharacterized protein. (859 aa)
	MYCTH_2296469	Uncharacterized protein. (871 aa)
	MYCTH_2294727	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
	MYCTH_2296615	EF-hand domain-containing protein. (2216 aa)
	MYCTH_2298542	Exo84_C domain-containing protein. (690 aa)
	MYCTH_2298622	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa)
	MYCTH_2296774	Uncharacterized protein. (1187 aa)
	MYCTH_2298680	Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (647 aa)
	MYCTH_2294980	DH domain-containing protein. (1585 aa)
	MYCTH_2298813	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1068 aa)
	MYCTH_2298826	Uncharacterized protein. (1163 aa)
	MYCTH_2314205	Uncharacterized protein. (205 aa)
	MYCTH_2297171	Uncharacterized protein. (382 aa)
	MYCTH_2297322	Uncharacterized protein. (205 aa)
	MYCTH_92028	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2044 aa)
	MYCTH_2299386	Peptidylprolyl isomerase. (84 aa)
	MYCTH_2295720	Uncharacterized protein. (1465 aa)
	MYCTH_2297462	Uncharacterized protein. (727 aa)
	MYCTH_2297483	Uncharacterized protein. (1488 aa)
	MYCTH_2295773	Rho-GAP domain-containing protein. (728 aa)
	MYCTH_2116312	Uncharacterized protein. (199 aa)
	MYCTH_2313954	SH3 domain-containing protein. (273 aa)
	MYCTH_2297751	Uncharacterized protein. (1282 aa)
	MYCTH_2302278	F-box domain-containing protein. (962 aa)
	MYCTH_2302369	SH3 domain-containing protein. (1312 aa)
	MYCTH_2302374	Sec8_exocyst domain-containing protein. (1102 aa)
	MYCTH_2125988	Uncharacterized protein. (603 aa)
	MYCTH_2302919	C2 domain-containing protein. (1085 aa)
	MYCTH_2301226	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1600 aa)
	MYCTH_2301261	Uncharacterized protein. (1846 aa)
	MYCTH_2301415	Uncharacterized protein. (769 aa)
	MYCTH_2090568	Uncharacterized protein. (161 aa)
	MYCTH_2300282	Uncharacterized protein. (179 aa)
	MYCTH_2302089	Uncharacterized protein. (174 aa)
	MYCTH_2032045	Uncharacterized protein. (160 aa)
	MYCTH_65137	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	MYCTH_2302145	Serine/threonine-protein phosphatase. (568 aa)
	MYCTH_2305012	Non-specific serine/threonine protein kinase. (845 aa)
	MYCTH_2305137	Uncharacterized protein. (1182 aa)
	MYCTH_2305231	Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (752 aa)
	MYCTH_2303375	Carbohydrate esterase family 4 protein. (259 aa)
	MYCTH_2303573	Rho-GAP domain-containing protein. (911 aa)
	MYCTH_2303602	Uncharacterized protein. (284 aa)
	MYCTH_2305614	Rho-GAP domain-containing protein. (655 aa)
	MYCTH_2303801	Uncharacterized protein. (197 aa)
	MYCTH_2303862	Uncharacterized protein. (169 aa)
	MYCTH_2304115	CRIB domain-containing protein. (852 aa)
	MYCTH_101679	Uncharacterized protein. (982 aa)
	MYCTH_2306850	Uncharacterized protein. (1044 aa)
	MYCTH_82189	Uncharacterized protein. (639 aa)
	MYCTH_2307317	Ras-GAP domain-containing protein. (1306 aa)
	MYCTH_2110837	Uncharacterized protein; Belongs to the calmodulin family. (148 aa)
	MYCTH_2065690	Protein kinase domain-containing protein. (331 aa)
	MYCTH_2307622	Uncharacterized protein. (776 aa)
	MYCTH_2306297	Sec3-PIP2_bind domain-containing protein. (1422 aa)
	MYCTH_2306441	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (628 aa)
	MYCTH_2306607	Uncharacterized protein. (773 aa)
	MYCTH_2307917	Uncharacterized protein. (835 aa)
	MYCTH_2112463	Uncharacterized protein. (567 aa)
	MYCTH_2144606	Uncharacterized protein. (1030 aa)
	MYCTH_2308172	Protein kinase domain-containing protein. (305 aa)
	MYCTH_2308595	Uncharacterized protein. (289 aa)
	MYCTH_2308614	Ras-GAP domain-containing protein. (835 aa)
	MYCTH_2308965	C2 domain-containing protein. (664 aa)
	MYCTH_2145069	Uncharacterized protein. (213 aa)
	MYCTH_2310488	Uncharacterized protein. (199 aa)
	MYCTH_2310546	Uncharacterized protein. (593 aa)
	MYCTH_2310551	Uncharacterized protein. (139 aa)
	MYCTH_2310610	DJ-1_PfpI domain-containing protein. (244 aa)
	MYCTH_2310888	Sec2p domain-containing protein. (660 aa)
	MYCTH_2312480	Ras-GAP domain-containing protein. (2633 aa)
	MYCTH_2316706	Uncharacterized protein. (194 aa)
	MYCTH_2312794	Uncharacterized protein. (285 aa)
	MYCTH_2312860	AIP3 domain-containing protein. (1034 aa)
	MYCTH_2312897	Uncharacterized protein; Belongs to the DOCK family. (2122 aa)
	MYCTH_2313005	Uncharacterized protein. (1211 aa)
	MYCTH_56516	Uncharacterized protein. (241 aa)
	MYCTH_2311655	Uncharacterized protein. (409 aa)
	MYCTH_2311673	Uncharacterized protein. (751 aa)
	MYCTH_2097277	Uncharacterized protein. (644 aa)
	MYCTH_72245	Uncharacterized protein. (169 aa)
	MYCTH_2312088	Uncharacterized protein. (809 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_101679	MYCTH_2297483	G2QEP6	G2Q5Z7	Uncharacterized protein.	Uncharacterized protein.	0.933
MYCTH_101679	MYCTH_2301261	G2QEP6	G2Q9D1	Uncharacterized protein.	Uncharacterized protein.	0.588
MYCTH_101679	MYCTH_2312860	G2QEP6	G2QNC1	Uncharacterized protein.	AIP3 domain-containing protein.	0.544
MYCTH_2032045	MYCTH_2090568	G2QB27	G2Q9L7	Uncharacterized protein.	Uncharacterized protein.	0.402
MYCTH_2032045	MYCTH_2097277	G2QB27	G2QPQ9	Uncharacterized protein.	Uncharacterized protein.	0.642
MYCTH_2032045	MYCTH_2297462	G2QB27	G2Q5Y4	Uncharacterized protein.	Uncharacterized protein.	0.446
MYCTH_2032045	MYCTH_2298826	G2QB27	G2Q3F7	Uncharacterized protein.	Uncharacterized protein.	0.928
MYCTH_2032045	MYCTH_2303602	G2QB27	G2QD69	Uncharacterized protein.	Uncharacterized protein.	0.486
MYCTH_2032045	MYCTH_2310546	G2QB27	G2QLN1	Uncharacterized protein.	Uncharacterized protein.	0.504
MYCTH_2032045	MYCTH_2313954	G2QB27	G2Q6Y6	Uncharacterized protein.	SH3 domain-containing protein.	0.421
MYCTH_2051419	MYCTH_2073197	G2PZQ9	G2Q012	Protein kinase domain-containing protein.	Uncharacterized protein.	0.733
MYCTH_2051419	MYCTH_2090568	G2PZQ9	G2Q9L7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.403
MYCTH_2051419	MYCTH_2097277	G2PZQ9	G2QPQ9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.642
MYCTH_2051419	MYCTH_2116312	G2PZQ9	G2Q6M1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_2296214	G2PZQ9	G2Q0Y9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.445
MYCTH_2051419	MYCTH_2297322	G2PZQ9	G2Q5G7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_2297462	G2PZQ9	G2Q5Y4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.475
MYCTH_2051419	MYCTH_2298826	G2PZQ9	G2Q3F7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.928
MYCTH_2051419	MYCTH_2303602	G2PZQ9	G2QD69	Protein kinase domain-containing protein.	Uncharacterized protein.	0.577
MYCTH_2051419	MYCTH_2303801	G2PZQ9	G2QDT0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.798

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