(46 nodes) Mixed, incl. Small GTPase mediated signal transduction, and Rho GTPase activation protein network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_2294051	Uncharacterized protein. (907 aa)
	MYCTH_2051419	Protein kinase domain-containing protein. (329 aa)
	MYCTH_2073197	Uncharacterized protein. (201 aa)
	MYCTH_2313989	Uncharacterized protein. (212 aa)
	MYCTH_2299840	Uncharacterized protein. (232 aa)
	MYCTH_2294147	ELMO domain-containing protein. (789 aa)
	MYCTH_2296774	Uncharacterized protein. (1187 aa)
	MYCTH_2294980	DH domain-containing protein. (1585 aa)
	MYCTH_2298826	Uncharacterized protein. (1163 aa)
	MYCTH_2297322	Uncharacterized protein. (205 aa)
	MYCTH_2295720	Uncharacterized protein. (1465 aa)
	MYCTH_2297462	Uncharacterized protein. (727 aa)
	MYCTH_2295773	Rho-GAP domain-containing protein. (728 aa)
	MYCTH_2116312	Uncharacterized protein. (199 aa)
	MYCTH_2313954	SH3 domain-containing protein. (273 aa)
	MYCTH_2297751	Uncharacterized protein. (1282 aa)
	MYCTH_2301261	Uncharacterized protein. (1846 aa)
	MYCTH_2301415	Uncharacterized protein. (769 aa)
	MYCTH_2300282	Uncharacterized protein. (179 aa)
	MYCTH_2032045	Uncharacterized protein. (160 aa)
	MYCTH_2305012	Non-specific serine/threonine protein kinase. (845 aa)
	MYCTH_2305137	Uncharacterized protein. (1182 aa)
	MYCTH_2303375	Carbohydrate esterase family 4 protein. (259 aa)
	MYCTH_2303573	Rho-GAP domain-containing protein. (911 aa)
	MYCTH_2305614	Rho-GAP domain-containing protein. (655 aa)
	MYCTH_2303801	Uncharacterized protein. (197 aa)
	MYCTH_82189	Uncharacterized protein. (639 aa)
	MYCTH_2307317	Ras-GAP domain-containing protein. (1306 aa)
	MYCTH_2065690	Protein kinase domain-containing protein. (331 aa)
	MYCTH_2306607	Uncharacterized protein. (773 aa)
	MYCTH_2144606	Uncharacterized protein. (1030 aa)
	MYCTH_2308172	Protein kinase domain-containing protein. (305 aa)
	MYCTH_2308595	Uncharacterized protein. (289 aa)
	MYCTH_2308965	C2 domain-containing protein. (664 aa)
	MYCTH_2145069	Uncharacterized protein. (213 aa)
	MYCTH_2310488	Uncharacterized protein. (199 aa)
	MYCTH_2310546	Uncharacterized protein. (593 aa)
	MYCTH_2312480	Ras-GAP domain-containing protein. (2633 aa)
	MYCTH_2316706	Uncharacterized protein. (194 aa)
	MYCTH_2312897	Uncharacterized protein; Belongs to the DOCK family. (2122 aa)
	MYCTH_2313005	Uncharacterized protein. (1211 aa)
	MYCTH_56516	Uncharacterized protein. (241 aa)
	MYCTH_2311655	Uncharacterized protein. (409 aa)
	MYCTH_2097277	Uncharacterized protein. (644 aa)
	MYCTH_72245	Uncharacterized protein. (169 aa)
	MYCTH_2312088	Uncharacterized protein. (809 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_2032045	MYCTH_2097277	G2QB27	G2QPQ9	Uncharacterized protein.	Uncharacterized protein.	0.642
MYCTH_2032045	MYCTH_2297462	G2QB27	G2Q5Y4	Uncharacterized protein.	Uncharacterized protein.	0.446
MYCTH_2032045	MYCTH_2298826	G2QB27	G2Q3F7	Uncharacterized protein.	Uncharacterized protein.	0.928
MYCTH_2032045	MYCTH_2310546	G2QB27	G2QLN1	Uncharacterized protein.	Uncharacterized protein.	0.504
MYCTH_2032045	MYCTH_2313954	G2QB27	G2Q6Y6	Uncharacterized protein.	SH3 domain-containing protein.	0.421
MYCTH_2051419	MYCTH_2073197	G2PZQ9	G2Q012	Protein kinase domain-containing protein.	Uncharacterized protein.	0.733
MYCTH_2051419	MYCTH_2097277	G2PZQ9	G2QPQ9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.642
MYCTH_2051419	MYCTH_2116312	G2PZQ9	G2Q6M1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_2297322	G2PZQ9	G2Q5G7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_2297462	G2PZQ9	G2Q5Y4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.475
MYCTH_2051419	MYCTH_2298826	G2PZQ9	G2Q3F7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.928
MYCTH_2051419	MYCTH_2303801	G2PZQ9	G2QDT0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.798
MYCTH_2051419	MYCTH_2310546	G2PZQ9	G2QLN1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.626
MYCTH_2051419	MYCTH_2311655	G2PZQ9	G2QPG0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_2313954	G2PZQ9	G2Q6Y6	Protein kinase domain-containing protein.	SH3 domain-containing protein.	0.421
MYCTH_2051419	MYCTH_2316706	G2PZQ9	G2QN52	Protein kinase domain-containing protein.	Uncharacterized protein.	0.426
MYCTH_2051419	MYCTH_56516	G2PZQ9	G2QPE7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2051419	MYCTH_72245	G2PZQ9	G2QQ18	Protein kinase domain-containing protein.	Uncharacterized protein.	0.424
MYCTH_2065690	MYCTH_2073197	G2QGD0	G2Q012	Protein kinase domain-containing protein.	Uncharacterized protein.	0.733
MYCTH_2065690	MYCTH_2097277	G2QGD0	G2QPQ9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.642

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