(14 nodes) Mixed, incl. Dynein complex, and Tubulin network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_2298035	Robl_LC7 domain-containing protein. (137 aa)
	MYCTH_2074571	Uncharacterized protein. (561 aa)
	MYCTH_2294321	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
	MYCTH_2087238	Uncharacterized protein. (115 aa)
	MYCTH_62074	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (105 aa)
	MYCTH_2074176	Uncharacterized protein. (191 aa)
	MYCTH_2297552	Uncharacterized protein. (154 aa)
	MYCTH_100290	Uncharacterized protein. (645 aa)
	MYCTH_2307379	Uncharacterized protein. (145 aa)
	MYCTH_2306723	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	MYCTH_96111	Protein kinase domain-containing protein. (1028 aa)
	MYCTH_2310162	Uncharacterized protein. (4346 aa)
	MYCTH_2311053	Uncharacterized protein. (538 aa)
	MYCTH_2312947	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (449 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_100290	MYCTH_2074571	G2Q7I4	G2Q0U0	Uncharacterized protein.	Uncharacterized protein.	0.626
MYCTH_100290	MYCTH_2294321	G2Q7I4	G2Q0U8	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.947
MYCTH_100290	MYCTH_2297552	G2Q7I4	G2Q625	Uncharacterized protein.	Uncharacterized protein.	0.512
MYCTH_100290	MYCTH_2298035	G2Q7I4	G2Q0L9	Uncharacterized protein.	Robl_LC7 domain-containing protein.	0.578
MYCTH_100290	MYCTH_2307379	G2Q7I4	G2QFN0	Uncharacterized protein.	Uncharacterized protein.	0.618
MYCTH_100290	MYCTH_2310162	G2Q7I4	G2QL49	Uncharacterized protein.	Uncharacterized protein.	0.925
MYCTH_100290	MYCTH_2312947	G2Q7I4	G2QNG4	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.947
MYCTH_100290	MYCTH_96111	G2Q7I4	G2QJI0	Uncharacterized protein.	Protein kinase domain-containing protein.	0.893
MYCTH_2074176	MYCTH_2074571	G2Q5P8	G2Q0U0	Uncharacterized protein.	Uncharacterized protein.	0.528
MYCTH_2074176	MYCTH_2294321	G2Q5P8	G2Q0U8	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.482
MYCTH_2074176	MYCTH_2297552	G2Q5P8	G2Q625	Uncharacterized protein.	Uncharacterized protein.	0.684
MYCTH_2074176	MYCTH_2307379	G2Q5P8	G2QFN0	Uncharacterized protein.	Uncharacterized protein.	0.406
MYCTH_2074176	MYCTH_2310162	G2Q5P8	G2QL49	Uncharacterized protein.	Uncharacterized protein.	0.753
MYCTH_2074176	MYCTH_2312947	G2Q5P8	G2QNG4	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.482
MYCTH_2074176	MYCTH_96111	G2Q5P8	G2QJI0	Uncharacterized protein.	Protein kinase domain-containing protein.	0.505
MYCTH_2074571	MYCTH_100290	G2Q0U0	G2Q7I4	Uncharacterized protein.	Uncharacterized protein.	0.626
MYCTH_2074571	MYCTH_2074176	G2Q0U0	G2Q5P8	Uncharacterized protein.	Uncharacterized protein.	0.528
MYCTH_2074571	MYCTH_2087238	G2Q0U0	G2Q194	Uncharacterized protein.	Uncharacterized protein.	0.913
MYCTH_2074571	MYCTH_2294321	G2Q0U0	G2Q0U8	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.972
MYCTH_2074571	MYCTH_2297552	G2Q0U0	G2Q625	Uncharacterized protein.	Uncharacterized protein.	0.483

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