(53 nodes) Mixed, incl. Phosphatase complex, and Cyclin A/B1/B2 associated events during G2/M transition network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_2294039	Protein kinase domain-containing protein. (1106 aa)
	MYCTH_2294137	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (463 aa)
	MYCTH_2294200	Rab-GAP TBC domain-containing protein. (340 aa)
	MYCTH_61755	Uncharacterized protein; Belongs to the protein kinase superfamily. (418 aa)
	MYCTH_74927	Non-specific serine/threonine protein kinase. (660 aa)
	MYCTH_2073132	Uncharacterized protein. (378 aa)
	MYCTH_2298433	Uncharacterized protein. (647 aa)
	MYCTH_2296595	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (480 aa)
	MYCTH_2073591	Serine/threonine-protein phosphatase. (327 aa)
	MYCTH_2298631	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (384 aa)
	MYCTH_2294802	Uncharacterized protein. (360 aa)
	MYCTH_2294923	AB hydrolase-1 domain-containing protein. (515 aa)
	MYCTH_2298895	Uncharacterized protein. (2703 aa)
	MYCTH_89669	Uncharacterized protein. (504 aa)
	MYCTH_2087754	N-acetyltransferase domain-containing protein. (206 aa)
	MYCTH_2299014	Serine/threonine-protein phosphatase. (481 aa)
	MYCTH_40930	Uncharacterized protein. (355 aa)
	MYCTH_2299079	SMK-1 domain-containing protein. (851 aa)
	MYCTH_2297312	FHA domain-containing protein. (745 aa)
	MYCTH_2295521	Protein kinase domain-containing protein. (710 aa)
	MYCTH_2295744	Protein kinase domain-containing protein. (879 aa)
	MYCTH_2295838	Serine/threonine-protein phosphatase. (531 aa)
	MYCTH_2297823	Metallophos domain-containing protein. (521 aa)
	MYCTH_2057956	Protein kinase domain-containing protein. (703 aa)
	MYCTH_2300618	Protein kinase domain-containing protein. (1380 aa)
	MYCTH_2300913	Uncharacterized protein. (1154 aa)
	MYCTH_2077959	Uncharacterized protein. (335 aa)
	MYCTH_2300230	Uncharacterized protein. (302 aa)
	MYCTH_2302206	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (677 aa)
	MYCTH_2080102	Uncharacterized protein. (624 aa)
	MYCTH_2305262	Uncharacterized protein. (290 aa)
	MYCTH_2138875	Uncharacterized protein. (1135 aa)
	MYCTH_107689	SET domain-containing protein. (589 aa)
	MYCTH_2306978	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (379 aa)
	MYCTH_2111553	Uncharacterized protein. (136 aa)
	MYCTH_2305972	Uncharacterized protein. (1281 aa)
	MYCTH_2306473	Uncharacterized protein. (347 aa)
	MYCTH_2307880	Uncharacterized protein. (549 aa)
	MYCTH_2308260	Uncharacterized protein. (875 aa)
	MYCTH_2308311	DUF1996 domain-containing protein. (405 aa)
	MYCTH_2310483	Serine/threonine-protein phosphatase. (322 aa)
	MYCTH_2312519	Uncharacterized protein. (181 aa)
	MYCTH_2312764	Uncharacterized protein. (276 aa)
	MYCTH_2311306	Uncharacterized protein. (860 aa)
	MYCTH_2311373	Uncharacterized protein. (371 aa)
	MYCTH_2311427	Uncharacterized protein. (1845 aa)
	MYCTH_2311558	Serine/threonine-protein phosphatase. (396 aa)
	MYCTH_2311589	Uncharacterized protein. (1832 aa)
	MYCTH_2311665	Uncharacterized protein. (980 aa)
	MYCTH_18938	Rab-GAP TBC domain-containing protein. (1052 aa)
	MYCTH_2130929	Uncharacterized protein. (1787 aa)
	MYCTH_2312297	Uncharacterized protein. (219 aa)
	MYCTH_2312336	Uncharacterized protein. (1015 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_107689	MYCTH_2073591	G2QE38	G2Q2H2	SET domain-containing protein.	Serine/threonine-protein phosphatase.	0.828
MYCTH_107689	MYCTH_2080102	G2QE38	G2QBJ0	SET domain-containing protein.	Uncharacterized protein.	0.873
MYCTH_107689	MYCTH_2296595	G2QE38	G2Q2B2	SET domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.739
MYCTH_107689	MYCTH_2297823	G2QE38	G2Q717	SET domain-containing protein.	Metallophos domain-containing protein.	0.828
MYCTH_107689	MYCTH_2302206	G2QE38	G2QB93	SET domain-containing protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.679
MYCTH_18938	MYCTH_2077959	G2QPJ4	G2Q9M3	Rab-GAP TBC domain-containing protein.	Uncharacterized protein.	0.715
MYCTH_18938	MYCTH_2138875	G2QPJ4	G2QDA2	Rab-GAP TBC domain-containing protein.	Uncharacterized protein.	0.463
MYCTH_18938	MYCTH_2296595	G2QPJ4	G2Q2B2	Rab-GAP TBC domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.508
MYCTH_18938	MYCTH_2312336	G2QPJ4	G2QQB4	Rab-GAP TBC domain-containing protein.	Uncharacterized protein.	0.520
MYCTH_2057956	MYCTH_2073591	G2Q7I7	G2Q2H2	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase.	0.692
MYCTH_2057956	MYCTH_2080102	G2Q7I7	G2QBJ0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.592
MYCTH_2057956	MYCTH_2294802	G2Q7I7	G2Q2N9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.446
MYCTH_2057956	MYCTH_2298433	G2Q7I7	G2Q217	Protein kinase domain-containing protein.	Uncharacterized protein.	0.578
MYCTH_2057956	MYCTH_2298895	G2Q7I7	G2Q3U8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.481
MYCTH_2057956	MYCTH_2300913	G2Q7I7	G2Q8H7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.691
MYCTH_2057956	MYCTH_2311306	G2Q7I7	G2QNS6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.744
MYCTH_2057956	MYCTH_2311373	G2Q7I7	G2QP06	Protein kinase domain-containing protein.	Uncharacterized protein.	0.846
MYCTH_2057956	MYCTH_2311665	G2Q7I7	G2QPG5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.832
MYCTH_2057956	MYCTH_2312297	G2Q7I7	G2QQ98	Protein kinase domain-containing protein.	Uncharacterized protein.	0.426
MYCTH_2057956	MYCTH_61755	G2Q7I7	G2Q0D0	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.562

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