(19 nodes) Regulation of TOR signaling network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	MYCTH_2294369	Uncharacterized protein. (376 aa)
	MYCTH_2296628	RIC1 domain-containing protein. (1110 aa)
	MYCTH_2296673	Uncharacterized protein. (610 aa)
	MYCTH_113066	FNIP_N domain-containing protein. (1394 aa)
	MYCTH_2298921	Uncharacterized protein. (979 aa)
	MYCTH_2299373	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (566 aa)
	MYCTH_2297855	WD_REPEATS_REGION domain-containing protein. (1634 aa)
	MYCTH_2302356	Rap-GAP domain-containing protein. (1651 aa)
	MYCTH_100654	Uncharacterized protein. (1549 aa)
	MYCTH_2117190	Uncharacterized protein. (418 aa)
	MYCTH_115624	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2793 aa)
	MYCTH_2304000	Zinc_ribbon_16 domain-containing protein. (828 aa)
	MYCTH_2079857	Uncharacterized protein. (410 aa)
	MYCTH_2306744	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (304 aa)
	MYCTH_17585	Uncharacterized protein. (76 aa)
	MYCTH_2307935	WD_REPEATS_REGION domain-containing protein. (1390 aa)
	MYCTH_2308721	UDENN FLCN/SMCR8-type domain-containing protein. (472 aa)
	MYCTH_2312940	Uncharacterized protein. (1118 aa)
	MYCTH_2311843	CNH domain-containing protein. (1100 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_100654	MYCTH_2312940	G2Q9K2	G2QNG1	Uncharacterized protein.	Uncharacterized protein.	0.560
MYCTH_113066	MYCTH_2308721	G2Q3G8	G2QK73	FNIP_N domain-containing protein.	UDENN FLCN/SMCR8-type domain-containing protein.	0.591
MYCTH_17585	MYCTH_2079857	G2QHJ6	G2QEI2	Uncharacterized protein.	Uncharacterized protein.	0.969
MYCTH_17585	MYCTH_2117190	G2QHJ6	G2Q9Z8	Uncharacterized protein.	Uncharacterized protein.	0.974
MYCTH_17585	MYCTH_2294369	G2QHJ6	G2Q180	Uncharacterized protein.	Uncharacterized protein.	0.907
MYCTH_17585	MYCTH_2296673	G2QHJ6	G2Q2E7	Uncharacterized protein.	Uncharacterized protein.	0.867
MYCTH_17585	MYCTH_2297855	G2QHJ6	G2Q732	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.685
MYCTH_17585	MYCTH_2299373	G2QHJ6	G2Q5Q5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.646
MYCTH_17585	MYCTH_2302356	G2QHJ6	G2Q7I2	Uncharacterized protein.	Rap-GAP domain-containing protein.	0.691
MYCTH_17585	MYCTH_2304000	G2QHJ6	G2QE45	Uncharacterized protein.	Zinc_ribbon_16 domain-containing protein.	0.685
MYCTH_17585	MYCTH_2306744	G2QHJ6	G2QES5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.621
MYCTH_17585	MYCTH_2307935	G2QHJ6	G2QIS1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.665
MYCTH_17585	MYCTH_2308721	G2QHJ6	G2QK73	Uncharacterized protein.	UDENN FLCN/SMCR8-type domain-containing protein.	0.845
MYCTH_2079857	MYCTH_17585	G2QEI2	G2QHJ6	Uncharacterized protein.	Uncharacterized protein.	0.969
MYCTH_2079857	MYCTH_2117190	G2QEI2	G2Q9Z8	Uncharacterized protein.	Uncharacterized protein.	0.999
MYCTH_2079857	MYCTH_2294369	G2QEI2	G2Q180	Uncharacterized protein.	Uncharacterized protein.	0.938
MYCTH_2079857	MYCTH_2296673	G2QEI2	G2Q2E7	Uncharacterized protein.	Uncharacterized protein.	0.975
MYCTH_2079857	MYCTH_2297855	G2QEI2	G2Q732	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.798
MYCTH_2079857	MYCTH_2298921	G2QEI2	G2Q3W1	Uncharacterized protein.	Uncharacterized protein.	0.448
MYCTH_2079857	MYCTH_2299373	G2QEI2	G2Q5Q5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.789

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