(31 nodes) Meiotic chromosome segregation network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_74764	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1772 aa)
	MYCTH_101105	Uncharacterized protein. (824 aa)
	MYCTH_2300329	Uncharacterized protein. (563 aa)
	MYCTH_2302206	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (677 aa)
	MYCTH_2305145	Uncharacterized protein. (1406 aa)
	MYCTH_2305146	Uncharacterized protein. (125 aa)
	MYCTH_2117988	Peptidase C50 domain-containing protein. (2077 aa)
	MYCTH_52807	Uncharacterized protein. (94 aa)
	MYCTH_2309406	Protein kinase domain-containing protein. (490 aa)
	MYCTH_2309487	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa)
	MYCTH_116885	DUF1767 domain-containing protein. (284 aa)
	MYCTH_2308845	Protein kinase domain-containing protein. (67 aa)
	MYCTH_2301930	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (811 aa)
	MYCTH_2116402	Uncharacterized protein. (1351 aa)
	MYCTH_74974	ERCC4 domain-containing protein. (947 aa)
	MYCTH_75070	Uncharacterized protein. (335 aa)
	MYCTH_2298274	UmuC domain-containing protein. (577 aa)
	MYCTH_2310469	DHR10 domain-containing protein. (454 aa)
	MYCTH_2135627	HTH APSES-type domain-containing protein. (441 aa)
	MYCTH_85534	Uncharacterized protein. (728 aa)
	MYCTH_2311906	Uncharacterized protein. (778 aa)
	MYCTH_56445	ERCC4 domain-containing protein. (718 aa)
	MYCTH_2298655	Csm1 domain-containing protein. (494 aa)
	MYCTH_2294870	Protein kinase domain-containing protein. (1009 aa)
	MYCTH_2050486	Uncharacterized protein. (242 aa)
	MYCTH_2298801	Uncharacterized protein. (829 aa)
	MYCTH_2031554	Rad21_Rec8 domain-containing protein. (653 aa)
	MYCTH_2297718	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
	MYCTH_2295859	ERCC4 domain-containing protein. (597 aa)
	MYCTH_27758	Uncharacterized protein. (105 aa)
	MYCTH_2301926	Uncharacterized protein. (413 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_116885	MYCTH_2295859	G2QK37	G2Q6U2	DUF1767 domain-containing protein.	ERCC4 domain-containing protein.	0.945
MYCTH_116885	MYCTH_74974	G2QK37	G2Q0N1	DUF1767 domain-containing protein.	ERCC4 domain-containing protein.	0.894
MYCTH_2031554	MYCTH_2116402	G2Q6D9	G2PZK1	Rad21_Rec8 domain-containing protein.	Uncharacterized protein.	0.448
MYCTH_2031554	MYCTH_2117988	G2Q6D9	G2QDA6	Rad21_Rec8 domain-containing protein.	Peptidase C50 domain-containing protein.	0.856
MYCTH_2031554	MYCTH_2294870	G2Q6D9	G2Q328	Rad21_Rec8 domain-containing protein.	Protein kinase domain-containing protein.	0.775
MYCTH_2031554	MYCTH_2295859	G2Q6D9	G2Q6U2	Rad21_Rec8 domain-containing protein.	ERCC4 domain-containing protein.	0.433
MYCTH_2031554	MYCTH_2298274	G2Q6D9	G2Q1J6	Rad21_Rec8 domain-containing protein.	UmuC domain-containing protein.	0.973
MYCTH_2031554	MYCTH_2305145	G2Q6D9	G2QC59	Rad21_Rec8 domain-containing protein.	Uncharacterized protein.	0.909
MYCTH_2031554	MYCTH_2305146	G2Q6D9	G2QC60	Rad21_Rec8 domain-containing protein.	Uncharacterized protein.	0.909
MYCTH_2116402	MYCTH_2031554	G2PZK1	G2Q6D9	Uncharacterized protein.	Rad21_Rec8 domain-containing protein.	0.448
MYCTH_2116402	MYCTH_2295859	G2PZK1	G2Q6U2	Uncharacterized protein.	ERCC4 domain-containing protein.	0.538
MYCTH_2116402	MYCTH_74764	G2PZK1	G2QL36	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.469
MYCTH_2117988	MYCTH_2031554	G2QDA6	G2Q6D9	Peptidase C50 domain-containing protein.	Rad21_Rec8 domain-containing protein.	0.856
MYCTH_2117988	MYCTH_2294870	G2QDA6	G2Q328	Peptidase C50 domain-containing protein.	Protein kinase domain-containing protein.	0.993
MYCTH_2117988	MYCTH_2298274	G2QDA6	G2Q1J6	Peptidase C50 domain-containing protein.	UmuC domain-containing protein.	0.740
MYCTH_2117988	MYCTH_2301926	G2QDA6	G2QAM0	Peptidase C50 domain-containing protein.	Uncharacterized protein.	0.406
MYCTH_2117988	MYCTH_2301930	G2QDA6	G2QAM3	Peptidase C50 domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.406
MYCTH_2117988	MYCTH_2302206	G2QDA6	G2QB93	Peptidase C50 domain-containing protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.679
MYCTH_2117988	MYCTH_2305145	G2QDA6	G2QC59	Peptidase C50 domain-containing protein.	Uncharacterized protein.	0.674
MYCTH_2117988	MYCTH_2305146	G2QDA6	G2QC60	Peptidase C50 domain-containing protein.	Uncharacterized protein.	0.674

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