(42 nodes) Cellular response to abiotic stimulus network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MYCTH_2052657	Uncharacterized protein. (482 aa)
	MYCTH_2305107	Uncharacterized protein. (913 aa)
	MYCTH_2303253	Uncharacterized protein. (806 aa)
	MYCTH_2305582	Zn(2)-C6 fungal-type domain-containing protein. (778 aa)
	MYCTH_2303885	Uncharacterized protein. (142 aa)
	MYCTH_2304244	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	MYCTH_2304498	Uncharacterized protein. (735 aa)
	MYCTH_2126860	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (461 aa)
	MYCTH_2307409	E3 ubiquitin-protein ligase. (811 aa)
	MYCTH_2065690	Protein kinase domain-containing protein. (331 aa)
	MYCTH_2306416	Non-specific serine/threonine protein kinase. (690 aa)
	MYCTH_2306475	Homoserine dehydrogenase. (367 aa)
	MYCTH_2306581	Uncharacterized protein. (381 aa)
	MYCTH_2112958	Uncharacterized protein. (239 aa)
	MYCTH_113577	Aldehyde dehydrogenase-like protein; Belongs to the aldehyde dehydrogenase family. (481 aa)
	MYCTH_2311136	Zn(2)-C6 fungal-type domain-containing protein. (120 aa)
	MYCTH_2300984	Zn(2)-C6 fungal-type domain-containing protein. (518 aa)
	MYCTH_2316413	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (296 aa)
	MYCTH_2311238	Uncharacterized protein. (254 aa)
	MYCTH_2097810	HPt domain-containing protein. (155 aa)
	MYCTH_2312900	Uncharacterized protein. (449 aa)
	MYCTH_109373	XPA_C domain-containing protein. (401 aa)
	MYCTH_2140820	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	MYCTH_2097168	Aldedh domain-containing protein. (472 aa)
	MYCTH_100654	Uncharacterized protein. (1549 aa)
	MYCTH_2314688	Uncharacterized protein. (251 aa)
	MYCTH_2300117	Uncharacterized protein. (1167 aa)
	MYCTH_2304698	Uncharacterized protein. (497 aa)
	MYCTH_2304802	Uncharacterized protein. (511 aa)
	MYCTH_2305012	Non-specific serine/threonine protein kinase. (845 aa)
	MYCTH_2051419	Protein kinase domain-containing protein. (329 aa)
	MYCTH_2142209	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
	MYCTH_2299913	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
	MYCTH_2294193	TYR_PHOSPHATASE_2 domain-containing protein. (664 aa)
	MYCTH_2296073	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	MYCTH_2296077	Vezatin domain-containing protein. (613 aa)
	MYCTH_2296333	MAP kinase kinase kinase. (1358 aa)
	MYCTH_2294799	BRO1 domain-containing protein. (496 aa)
	MYCTH_2296734	Protein phosphatase; Belongs to the PP2C family. (465 aa)
	MYCTH_2294928	Uncharacterized protein. (1326 aa)
	MYCTH_2086391	Uncharacterized protein; Belongs to the heat shock protein 70 family. (667 aa)
	MYCTH_2297347	Protein kinase domain-containing protein. (669 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_109373	MYCTH_2142209	G2QNS7	G2PZY9	XPA_C domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.702
MYCTH_109373	MYCTH_2296073	G2QNS7	G2Q0G3	XPA_C domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.476
MYCTH_109373	MYCTH_2296077	G2QNS7	G2Q0G4	XPA_C domain-containing protein.	Vezatin domain-containing protein.	0.476
MYCTH_109373	MYCTH_2306581	G2QNS7	G2QHL5	XPA_C domain-containing protein.	Uncharacterized protein.	0.978
MYCTH_2051419	MYCTH_2305107	G2PZQ9	G2QC44	Protein kinase domain-containing protein.	Uncharacterized protein.	0.407
MYCTH_2051419	MYCTH_2316413	G2PZQ9	G2QMQ3	Protein kinase domain-containing protein.	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.471
MYCTH_2065690	MYCTH_2305107	G2QGD0	G2QC44	Protein kinase domain-containing protein.	Uncharacterized protein.	0.407
MYCTH_2065690	MYCTH_2316413	G2QGD0	G2QMQ3	Protein kinase domain-containing protein.	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.471
MYCTH_2097810	MYCTH_2294928	G2QN57	G2Q347	HPt domain-containing protein.	Uncharacterized protein.	0.672
MYCTH_2097810	MYCTH_2296333	G2QN57	G2Q1E5	HPt domain-containing protein.	MAP kinase kinase kinase.	0.602
MYCTH_2097810	MYCTH_2297347	G2QN57	G2Q5H9	HPt domain-containing protein.	Protein kinase domain-containing protein.	0.725
MYCTH_2097810	MYCTH_2300117	G2QN57	G2QAG0	HPt domain-containing protein.	Uncharacterized protein.	0.996
MYCTH_2097810	MYCTH_2304698	G2QN57	G2QBH7	HPt domain-containing protein.	Uncharacterized protein.	0.443
MYCTH_2097810	MYCTH_2305107	G2QN57	G2QC44	HPt domain-containing protein.	Uncharacterized protein.	0.465
MYCTH_2097810	MYCTH_2316413	G2QN57	G2QMQ3	HPt domain-containing protein.	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.536
MYCTH_2126860	MYCTH_2306581	G2QES2	G2QHL5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.583
MYCTH_2140820	MYCTH_2299913	G2QPB2	G2Q091	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.904
MYCTH_2140820	MYCTH_2304244	G2QPB2	G2QED6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.902
MYCTH_2142209	MYCTH_109373	G2PZY9	G2QNS7	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	XPA_C domain-containing protein.	0.702
MYCTH_2142209	MYCTH_2296073	G2PZY9	G2Q0G3	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.751

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