(139 nodes) Supramolecular complex network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MYCTH_2315082	TCTP domain-containing protein; Belongs to the TCTP family. (170 aa)
	MYCTH_2295934	CAP-Gly domain-containing protein. (862 aa)
	MYCTH_2295985	Protein kinase domain-containing protein. (878 aa)
	MYCTH_2297896	CENP-T_C domain-containing protein. (504 aa)
	MYCTH_2294193	TYR_PHOSPHATASE_2 domain-containing protein. (664 aa)
	MYCTH_2296128	CS domain-containing protein. (188 aa)
	MYCTH_2294310	CAP-Gly domain-containing protein. (631 aa)
	MYCTH_2294321	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
	MYCTH_2050996	Spc7 domain-containing protein. (728 aa)
	MYCTH_2031956	Uncharacterized protein. (494 aa)
	MYCTH_2313667	Uncharacterized protein. (324 aa)
	MYCTH_75070	Uncharacterized protein. (335 aa)
	MYCTH_2296319	S1 motif domain-containing protein; Belongs to the RNR ribonuclease family. (988 aa)
	MYCTH_2313336	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (249 aa)
	MYCTH_2296480	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
	MYCTH_62074	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (105 aa)
	MYCTH_2294655	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1013 aa)
	MYCTH_2296591	Uncharacterized protein. (317 aa)
	MYCTH_110536	RPOL4c domain-containing protein. (146 aa)
	MYCTH_2296663	HTH La-type RNA-binding domain-containing protein. (1019 aa)
	MYCTH_2298566	WD_REPEATS_REGION domain-containing protein. (351 aa)
	MYCTH_2298622	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa)
	MYCTH_2298655	Csm1 domain-containing protein. (494 aa)
	MYCTH_2294870	Protein kinase domain-containing protein. (1009 aa)
	MYCTH_2123230	Uncharacterized protein. (171 aa)
	MYCTH_2296876	Protein kinase domain-containing protein. (919 aa)
	MYCTH_43727	Carbohydrate esterase family 3 protein. (232 aa)
	MYCTH_2298825	Uncharacterized protein. (1152 aa)
	MYCTH_2137175	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (128 aa)
	MYCTH_2299067	Uncharacterized protein. (72 aa)
	MYCTH_2299193	Spindle pole body component. (972 aa)
	MYCTH_2299223	Spindle pole body component. (1065 aa)
	MYCTH_73682	Uncharacterized protein. (742 aa)
	MYCTH_2299301	Uncharacterized protein. (199 aa)
	MYCTH_2115401	Uncharacterized protein. (340 aa)
	MYCTH_92028	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2044 aa)
	MYCTH_2052991	Uncharacterized protein. (193 aa)
	MYCTH_2295817	Uncharacterized protein. (1150 aa)
	MYCTH_2297656	Uncharacterized protein. (1085 aa)
	MYCTH_2293965	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1120 aa)
	MYCTH_2299718	NUDE_C domain-containing protein. (634 aa)
	MYCTH_2302341	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (701 aa)
	MYCTH_100290	Uncharacterized protein. (645 aa)
	MYCTH_2300583	Uncharacterized protein. (599 aa)
	MYCTH_2300670	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (362 aa)
	MYCTH_2090056	PUA domain-containing protein. (490 aa)
	MYCTH_2302632	Uncharacterized protein. (867 aa)
	MYCTH_2300775	Uncharacterized protein. (639 aa)
	MYCTH_2300799	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (918 aa)
	MYCTH_2302755	Spindle pole body component. (987 aa)
	MYCTH_2300990	Spindle pole body component. (919 aa)
	MYCTH_2301280	Uncharacterized protein. (653 aa)
	MYCTH_92876	Uncharacterized protein. (1055 aa)
	MYCTH_2301470	RNB domain-containing protein. (1339 aa)
	MYCTH_2090568	Uncharacterized protein. (161 aa)
	MYCTH_2124743	Uncharacterized protein. (61 aa)
	MYCTH_2138386	Uncharacterized protein. (452 aa)
	MYCTH_2301916	Endo/exonuclease/phosphatase domain-containing protein. (761 aa)
	MYCTH_2301926	Uncharacterized protein. (413 aa)
	MYCTH_2301930	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (811 aa)
	MYCTH_101105	Uncharacterized protein. (824 aa)
	MYCTH_2300265	GFA domain-containing protein. (135 aa)
	MYCTH_2300329	Uncharacterized protein. (563 aa)
	MYCTH_2133532	Uncharacterized protein. (485 aa)
	MYCTH_2302206	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (677 aa)
	MYCTH_2304592	Uncharacterized protein. (769 aa)
	MYCTH_2304624	Uncharacterized protein. (734 aa)
	MYCTH_2126987	Uncharacterized protein. (366 aa)
	MYCTH_2304848	Uncharacterized protein. (508 aa)
	MYCTH_2304889	Uncharacterized protein. (595 aa)
	MYCTH_2315322	eRF1_1 domain-containing protein. (435 aa)
	MYCTH_2118584	RRM_2 domain-containing protein. (634 aa)
	MYCTH_2305264	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
	MYCTH_2305340	Uncharacterized protein. (243 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	MYCTH_2305382	Uncharacterized protein. (446 aa)
	MYCTH_2303499	MIF4G domain-containing protein. (1469 aa)
	MYCTH_2303522	Uncharacterized protein. (500 aa)
	MYCTH_2303547	Nudix hydrolase domain-containing protein. (869 aa)
	MYCTH_2303558	Uncharacterized protein. (314 aa)
	MYCTH_2303808	Uncharacterized protein. (814 aa)
	MYCTH_67855	Histone H3-like protein. (159 aa)
	MYCTH_2315190	SAM domain-containing protein. (606 aa)
	MYCTH_2306791	Uncharacterized protein. (356 aa)
	MYCTH_2306820	SurE domain-containing protein. (926 aa)
	MYCTH_2306855	Uncharacterized protein. (2188 aa)
	MYCTH_2307398	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (462 aa)
	MYCTH_2307420	WD_REPEATS_REGION domain-containing protein. (613 aa)
	MYCTH_2307475	Uncharacterized protein. (652 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (461 aa)
	MYCTH_2305849	Uncharacterized protein. (922 aa)
	MYCTH_53698	Carbohydrate esterase family 3 protein. (235 aa)
	MYCTH_2307782	HORMA domain-containing protein. (252 aa)
	MYCTH_2306157	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (960 aa)
	MYCTH_2119140	Uncharacterized protein. (650 aa)
	MYCTH_2306723	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	MYCTH_2307849	Zn(2)-C6 fungal-type domain-containing protein. (924 aa)
	MYCTH_2307917	Uncharacterized protein. (835 aa)
	MYCTH_2112463	Uncharacterized protein. (567 aa)
	MYCTH_83111	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (756 aa)
	MYCTH_2308106	GFA domain-containing protein. (155 aa)
	MYCTH_2308140	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (648 aa)
	MYCTH_2308335	Uncharacterized protein; Belongs to the DEAD box helicase family. (549 aa)
	MYCTH_2308360	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (933 aa)
	MYCTH_71014	Uncharacterized protein. (375 aa)
	MYCTH_2308513	Uncharacterized protein. (143 aa)
	MYCTH_2308748	C-CAP/cofactor C-like domain-containing protein. (382 aa)
	MYCTH_2309747	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (940 aa)
	MYCTH_2096067	Uncharacterized protein. (324 aa)
	MYCTH_2310162	Uncharacterized protein. (4346 aa)
	MYCTH_2310167	Spindle pole body component. (797 aa)
	MYCTH_98099	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1149 aa)
	MYCTH_2310439	PAT1 domain-containing protein. (854 aa)
	MYCTH_2310469	DHR10 domain-containing protein. (454 aa)
	MYCTH_2310562	Uncharacterized protein. (848 aa)
	MYCTH_2310567	Uncharacterized protein. (756 aa)
	MYCTH_2310628	Glycosyltransferase family 69 protein. (430 aa)
	MYCTH_74402	Tubulin-tyrosine ligase-like protein. (512 aa)
	MYCTH_2140615	Uncharacterized protein. (678 aa)
	MYCTH_2310997	NTP_transf_9 domain-containing protein. (169 aa)
	MYCTH_2311053	Uncharacterized protein. (538 aa)
	MYCTH_2311201	Uncharacterized protein. (175 aa)
	MYCTH_2312622	CAP-Gly domain-containing protein. (240 aa)
	MYCTH_96554	Uncharacterized protein. (308 aa)
	MYCTH_2312813	Uncharacterized protein. (184 aa)
	MYCTH_2312856	LsmAD domain-containing protein. (1053 aa)
	MYCTH_2312947	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (449 aa)
	MYCTH_2313107	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (905 aa)
	MYCTH_109377	Uncharacterized protein. (1884 aa)
	MYCTH_85534	Uncharacterized protein. (728 aa)
	MYCTH_2311445	Uncharacterized protein. (566 aa)
	MYCTH_2316492	Uncharacterized protein. (566 aa)
	MYCTH_2311723	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (337 aa)
	MYCTH_2311897	UmuC domain-containing protein. (591 aa)
	MYCTH_17562	Uncharacterized protein. (129 aa)
	MYCTH_117436	Uncharacterized protein. (254 aa)
	MYCTH_2312047	Uncharacterized protein. (120 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (159 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM1	LSM3	G2QQ96	G2QCL7	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
LSM1	LSM4	G2QQ96	G2Q4A5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
LSM1	MYCTH_2137175	G2QQ96	G2Q463	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.964
LSM1	MYCTH_2138386	G2QQ96	G2QA94	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.784
LSM1	MYCTH_2296591	G2QQ96	G2Q2B1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.964
LSM1	MYCTH_2301916	G2QQ96	G2QAL5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Endo/exonuclease/phosphatase domain-containing protein.	0.493
LSM1	MYCTH_2303547	G2QQ96	G2QCZ1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Nudix hydrolase domain-containing protein.	0.787
LSM1	MYCTH_2303558	G2QQ96	G2QCZ3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.787
LSM1	MYCTH_2304592	G2QQ96	G2QBD1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.791
LSM1	MYCTH_2306855	G2QQ96	G2QEX3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.404
LSM1	MYCTH_2308335	G2QQ96	G2QJN9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.974
LSM1	MYCTH_2310439	G2QQ96	G2QLI2	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	PAT1 domain-containing protein.	0.996
LSM1	MYCTH_2310997	G2QQ96	G2QME8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.633
LSM1	MYCTH_2313336	G2QQ96	G2Q1R7	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.461
LSM1	MYCTH_2316492	G2QQ96	G2QPF4	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.574
LSM1	MYCTH_92876	G2QQ96	G2Q9H6	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.978
LSM3	LSM1	G2QCL7	G2QQ96	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.998
LSM3	LSM4	G2QCL7	G2Q4A5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	MYCTH_2137175	G2QCL7	G2Q463	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
LSM3	MYCTH_2138386	G2QCL7	G2QA94	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.800

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