(46 nodes) HAD superfamily network (Thermothelomyces thermophilus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYCTH_2315383	Uncharacterized protein. (534 aa)
	MYCTH_2061857	HMA domain-containing protein. (1119 aa)
	MYCTH_2305576	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1318 aa)
	MYCTH_111604	4-nitrophenylphosphatase. (307 aa)
	UTR4	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (239 aa)
	MYCTH_2304292	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1354 aa)
	MYCTH_2306817	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1429 aa)
	MYCTH_2093327	Uncharacterized protein. (478 aa)
	MYCTH_2305754	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1176 aa)
	MYCTH_2307663	Uncharacterized protein. (477 aa)
	MYCTH_102797	ATPase, P type cation/copper-transporter. (1223 aa)
	MYCTH_2307846	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (546 aa)
	MYCTH_2309412	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (913 aa)
	MYCTH_2309547	Glycosyltransferase family 20 protein. (1038 aa)
	MYCTH_2309634	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1263 aa)
	MYCTH_70861	Uncharacterized protein. (251 aa)
	MYCTH_2310289	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1309 aa)
	MYCTH_2310306	Uncharacterized protein. (234 aa)
	MYCTH_2310422	Uncharacterized protein. (257 aa)
	MYCTH_2130079	Uncharacterized protein. (375 aa)
	MYCTH_2312579	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (920 aa)
	MYCTH_2083946	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1384 aa)
	MYCTH_2297984	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1538 aa)
	MYCTH_2296156	LNS2 domain-containing protein. (787 aa)
	MYCTH_2294253	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1073 aa)
	MYCTH_2294274	FCP1 homology domain-containing protein. (486 aa)
	MYCTH_2298134	Uncharacterized protein. (472 aa)
	MYCTH_2294433	Uncharacterized protein. (1159 aa)
	MYCTH_2296323	Uncharacterized protein. (245 aa)
	MYCTH_2294817	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
	MYCTH_2294943	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (265 aa)
	MYCTH_2297033	Uncharacterized protein. (358 aa)
	MYCTH_2050929	Uncharacterized protein. (238 aa)
	MYCTH_2295490	Glycosyltransferase family 20 protein. (905 aa)
	MYCTH_2297601	Uncharacterized protein. (493 aa)
	MYCTH_2299555	Uncharacterized protein. (327 aa)
	MYCTH_2293966	Uncharacterized protein. (268 aa)
	MYCTH_2302773	Uncharacterized protein. (279 aa)
	MYCTH_2302800	FCP1 homology domain-containing protein. (524 aa)
	MYCTH_2300903	Uncharacterized protein. (246 aa)
	MYCTH_2116929	Uncharacterized protein. (215 aa)
	MYCTH_2301237	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1343 aa)
	MYCTH_2301640	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1614 aa)
	MYCTH_2299969	Uncharacterized protein. (310 aa)
	MYCTH_2058349	FCP1 homology domain-containing protein. (271 aa)
	MYCTH_2302129	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1336 aa)

Your Current Organism:

Thermothelomyces thermophilus

NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYCTH_2058349	MYCTH_2296156	G2QAZ0	G2Q0K4	FCP1 homology domain-containing protein.	LNS2 domain-containing protein.	0.793
MYCTH_2083946	MYCTH_2302129	G2QLZ0	G2QB66	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.565
MYCTH_2093327	MYCTH_2298134	G2QFJ8	G2Q128	Uncharacterized protein.	Uncharacterized protein.	0.486
MYCTH_2294253	MYCTH_2305576	G2Q0R7	G2QDF0	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.411
MYCTH_2294253	MYCTH_2306817	G2Q0R7	G2QEV5	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.776
MYCTH_2294253	MYCTH_2309634	G2Q0R7	G2QJ15	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.777
MYCTH_2294253	MYCTH_2310289	G2Q0R7	G2QLB5	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.780
MYCTH_2294274	MYCTH_2296156	G2Q0S4	G2Q0K4	FCP1 homology domain-containing protein.	LNS2 domain-containing protein.	0.793
MYCTH_2294274	MYCTH_2309412	G2Q0S4	G2QIB9	FCP1 homology domain-containing protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.521
MYCTH_2294817	MYCTH_2305576	G2Q2P8	G2QDF0	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.400
MYCTH_2294817	MYCTH_2306817	G2Q2P8	G2QEV5	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.668
MYCTH_2294817	MYCTH_2309634	G2Q2P8	G2QJ15	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.668
MYCTH_2294817	MYCTH_2310289	G2Q2P8	G2QLB5	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.671
MYCTH_2294943	MYCTH_2295490	G2Q352	G2Q4Z8	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	Glycosyltransferase family 20 protein.	0.521
MYCTH_2294943	MYCTH_2297601	G2Q352	G2Q6F4	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	Uncharacterized protein.	0.492
MYCTH_2294943	MYCTH_2307663	G2Q352	G2QGJ5	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	Uncharacterized protein.	0.492
MYCTH_2294943	MYCTH_2309547	G2Q352	G2QIP9	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	Glycosyltransferase family 20 protein.	0.521
MYCTH_2295490	MYCTH_2294943	G2Q4Z8	G2Q352	Glycosyltransferase family 20 protein.	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	0.521
MYCTH_2295490	MYCTH_2309547	G2Q4Z8	G2QIP9	Glycosyltransferase family 20 protein.	Glycosyltransferase family 20 protein.	0.994
MYCTH_2296156	MYCTH_2058349	G2Q0K4	G2QAZ0	LNS2 domain-containing protein.	FCP1 homology domain-containing protein.	0.793

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