STRINGSTRING
MYCTH_2142209 MYCTH_2142209 MYCTH_40109 MYCTH_40109 MYCTH_2049865 MYCTH_2049865 MYCTH_2296191 MYCTH_2296191 MYCTH_2296197 MYCTH_2296197 MYCTH_2298243 MYCTH_2298243 MYCTH_2296558 MYCTH_2296558 MYCTH_2296626 MYCTH_2296626 MYCTH_37094 MYCTH_37094 MYCTH_2298552 MYCTH_2298552 MYCTH_2294864 MYCTH_2294864 MYCTH_2296914 MYCTH_2296914 MYCTH_2298922 MYCTH_2298922 MYCTH_2089183 MYCTH_2089183 MYCTH_2300427 MYCTH_2300427 MYCTH_66289 MYCTH_66289 MYCTH_87315 MYCTH_87315 MYCTH_2302632 MYCTH_2302632 MYCTH_2302646 MYCTH_2302646 MYCTH_2301169 MYCTH_2301169 MYCTH_79116 MYCTH_79116 MYCTH_2300099 MYCTH_2300099 MYCTH_2116523 MYCTH_2116523 MYCTH_2300159 MYCTH_2300159 MYCTH_2300173 MYCTH_2300173 MYCTH_2302095 MYCTH_2302095 MYCTH_2304608 MYCTH_2304608 MYCTH_2080045 MYCTH_2080045 MYCTH_2304659 MYCTH_2304659 MYCTH_2304663 MYCTH_2304663 MYCTH_101588 MYCTH_101588 MYCTH_115624 MYCTH_115624 MYCTH_2305051 MYCTH_2305051 MYCTH_2303567 MYCTH_2303567 MDM34 MDM34 MYCTH_2306759 MYCTH_2306759 MYCTH_2046198 MYCTH_2046198 MYCTH_2307049 MYCTH_2307049 MYCTH_2307068 MYCTH_2307068 MYCTH_2307148 MYCTH_2307148 MYCTH_2307354 MYCTH_2307354 MYCTH_83051 MYCTH_83051 MYCTH_111987 MYCTH_111987 MYCTH_17585 MYCTH_17585 MYCTH_2306649 MYCTH_2306649 MYCTH_2306730 MYCTH_2306730 MYCTH_2067869 MYCTH_2067869 MYCTH_2309135 MYCTH_2309135 MYCTH_2309334 MYCTH_2309334 MYCTH_2307926 MYCTH_2307926 MYCTH_2308236 MYCTH_2308236 MYCTH_2308902 MYCTH_2308902 MYCTH_2120170 MYCTH_2120170 MYCTH_2309816 MYCTH_2309816 MYCTH_2310306 MYCTH_2310306 MYCTH_2311046 MYCTH_2311046 MYCTH_2311053 MYCTH_2311053 MYCTH_2311549 MYCTH_2311549 MYCTH_2311550 MYCTH_2311550 MYCTH_2311835 MYCTH_2311835 MYCTH_2070906 MYCTH_2070906 MYCTH_2311956 MYCTH_2311956 MYCTH_2316579 MYCTH_2316579
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYCTH_2142209UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
MYCTH_40109Phosphatidylinositol 3-kinase VPS34. (903 aa)
MYCTH_2049865DJ-1_PfpI domain-containing protein. (222 aa)
MYCTH_2296191Uncharacterized protein. (499 aa)
MYCTH_2296197Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (378 aa)
MYCTH_2298243Autophagy-related protein 3. (344 aa)
MYCTH_2296558ATG11 domain-containing protein. (1423 aa)
MYCTH_2296626Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (277 aa)
MYCTH_37094Uncharacterized protein. (1480 aa)
MYCTH_2298552Uncharacterized protein. (190 aa)
MYCTH_2294864Autophagy_act_C domain-containing protein. (248 aa)
MYCTH_2296914TPR_REGION domain-containing protein. (595 aa)
MYCTH_2298922DJ-1_PfpI domain-containing protein. (289 aa)
MYCTH_2089183Zn(2)-C6 fungal-type domain-containing protein. (829 aa)
MYCTH_2300427Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (695 aa)
MYCTH_66289Uncharacterized protein. (227 aa)
MYCTH_87315Uncharacterized protein. (53 aa)
MYCTH_2302632Uncharacterized protein. (867 aa)
MYCTH_2302646Uncharacterized protein. (621 aa)
MYCTH_2301169USP domain-containing protein; Belongs to the peptidase C19 family. (777 aa)
MYCTH_79116Uncharacterized protein. (353 aa)
MYCTH_2300099Uncharacterized protein. (278 aa)
MYCTH_2116523Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (282 aa)
MYCTH_2300159Non-specific serine/threonine protein kinase. (726 aa)
MYCTH_2300173Uncharacterized protein. (211 aa)
MYCTH_2302095Carbohydrate-binding module family 48 protein. (463 aa)
MYCTH_2304608ATG16 domain-containing protein. (209 aa)
MYCTH_2080045Uncharacterized protein. (169 aa)
MYCTH_2304659Uncharacterized protein. (225 aa)
MYCTH_2304663Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (929 aa)
MYCTH_101588Myotubularin phosphatase domain-containing protein. (809 aa)
MYCTH_115624Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2793 aa)
MYCTH_2305051Uncharacterized protein. (260 aa)
MYCTH_2303567Protein kinase domain-containing protein. (978 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (536 aa)
MYCTH_2306759Non-specific serine/threonine protein kinase. (817 aa)
MYCTH_2046198Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (845 aa)
MYCTH_2307049Uncharacterized protein. (178 aa)
MYCTH_2307068Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (341 aa)
MYCTH_2307148Fungal_trans domain-containing protein. (696 aa)
MYCTH_2307354Carbohydrate-binding module family 48 protein. (712 aa)
MYCTH_83051Uncharacterized protein. (133 aa)
MYCTH_111987UBIQUITIN_CONJUGAT_2 domain-containing protein. (156 aa)
MYCTH_17585Uncharacterized protein. (76 aa)
MYCTH_2306649Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (143 aa)
MYCTH_2306730BZIP domain-containing protein. (305 aa)
MYCTH_2067869Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (456 aa)
MYCTH_2309135Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (895 aa)
MYCTH_2309334Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (516 aa)
MYCTH_2307926Uncharacterized protein. (642 aa)
MYCTH_2308236Ubiquitin-like domain-containing protein. (127 aa)
MYCTH_2308902Protein kinase domain-containing protein. (309 aa)
MYCTH_2120170Protein kinase domain-containing protein. (943 aa)
MYCTH_2309816Uncharacterized protein. (474 aa)
MYCTH_2310306Uncharacterized protein. (234 aa)
MYCTH_2311046Uncharacterized protein. (427 aa)
MYCTH_2311053Uncharacterized protein. (538 aa)
MYCTH_2311549Uncharacterized protein. (74 aa)
MYCTH_2311550Uncharacterized protein. (332 aa)
MYCTH_2311835Autophagy-related protein. (121 aa)
MYCTH_2070906DJ-1_PfpI domain-containing protein. (271 aa)
MYCTH_2311956Uncharacterized protein. (209 aa)
MYCTH_2316579Uncharacterized protein. (251 aa)
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.