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MYCTH_2296197 MYCTH_2296197 MDM12 MDM12 MYCTH_2296480 MYCTH_2296480 MYCTH_2296558 MYCTH_2296558 MYCTH_2296626 MYCTH_2296626 MYCTH_99040 MYCTH_99040 MYCTH_2299299 MYCTH_2299299 MYCTH_2297347 MYCTH_2297347 MYCTH_2299571 MYCTH_2299571 MYCTH_2294001 MYCTH_2294001 MYCTH_2302790 MYCTH_2302790 MYCTH_2301009 MYCTH_2301009 MYCTH_2300117 MYCTH_2300117 MYCTH_2304990 MYCTH_2304990 MDM10 MDM10 MYCTH_2303567 MYCTH_2303567 MYCTH_81343 MYCTH_81343 MMM1 MMM1 MDM34 MDM34 MYCTH_2307068 MYCTH_2307068 MYCTH_2307294 MYCTH_2307294 MYCTH_2306255 MYCTH_2306255 MYCTH_2315848 MYCTH_2315848 MYCTH_2308809 MYCTH_2308809 MYCTH_2309838 MYCTH_2309838 MYCTH_2316209 MYCTH_2316209 MYCTH_2310921 MYCTH_2310921 MYCTH_2311481 MYCTH_2311481 MYCTH_2311706 MYCTH_2311706 MYCTH_2311835 MYCTH_2311835
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYCTH_2296197Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (378 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (552 aa)
MYCTH_2296480Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
MYCTH_2296558ATG11 domain-containing protein. (1423 aa)
MYCTH_2296626Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (277 aa)
MYCTH_99040HDAC_interact domain-containing protein. (1713 aa)
MYCTH_2299299Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (153 aa)
MYCTH_2297347Protein kinase domain-containing protein. (669 aa)
MYCTH_2299571Uncharacterized protein. (224 aa)
MYCTH_2294001Letm1 RBD domain-containing protein. (555 aa)
MYCTH_2302790Ubiquitin carboxyl-terminal hydrolase. (950 aa)
MYCTH_2301009Small nuclear ribonucleoprotein Sm D3. (114 aa)
MYCTH_2300117Uncharacterized protein. (1167 aa)
MYCTH_2304990POLAc domain-containing protein. (1198 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (458 aa)
MYCTH_2303567Protein kinase domain-containing protein. (978 aa)
MYCTH_81343MAP kinase-like protein. (525 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (420 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (536 aa)
MYCTH_2307068Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (341 aa)
MYCTH_2307294Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2438 aa)
MYCTH_2306255Uncharacterized protein. (131 aa)
MYCTH_2315848WSC domain-containing protein. (290 aa)
MYCTH_2308809PIPK domain-containing protein. (993 aa)
MYCTH_2309838Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
MYCTH_2316209WSC domain-containing protein. (331 aa)
MYCTH_2310921Response regulatory domain-containing protein. (798 aa)
MYCTH_2311481PPM-type phosphatase domain-containing protein. (600 aa)
MYCTH_2311706AAA domain-containing protein. (746 aa)
MYCTH_2311835Autophagy-related protein. (121 aa)
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
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