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hemA hemA ADL12085.1 ADL12085.1 hemC hemC ADL12087.1 ADL12087.1 ADL12088.1 ADL12088.1 hemL hemL ADL12143.1 ADL12143.1 ADL12176.1 ADL12176.1 cobT cobT ADL12365.1 ADL12365.1 cbiD cbiD ADL12367.1 ADL12367.1 ADL12368.1 ADL12368.1 ADL12369.1 ADL12369.1 ADL12370.1 ADL12370.1 ADL12371.1 ADL12371.1 ADL12372.1 ADL12372.1 ADL12373.1 ADL12373.1 ADL12374.1 ADL12374.1 cobQ cobQ cobQ-2 cobQ-2 cobD cobD cbiA cbiA ADL12379.1 ADL12379.1 cobS cobS ADL12381.1 ADL12381.1 ADL12382.1 ADL12382.1 ADL12383.1 ADL12383.1 ADL12476.1 ADL12476.1
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second shell of interactors
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proteins of unknown 3D structure
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hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (427 aa)
ADL12085.1COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040:IPR006367; KEGG: dae:Dtox_1249 siroheme synthase; PRIAM: Sirohydrochlorin ferrochelatase; SPTR: A5D3L3 Siroheme synthase; TIGRFAM: siroheme synthase; PFAM: Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain. (221 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (314 aa)
ADL12087.1COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR014777:IPR014776:IPR003043:IPR000878:IPR 003754:IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A5D3L6 Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. (501 aa)
ADL12088.1Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR013785:IPR001731; KEGG: tpd:Teth39_1889 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: C6Q7Q1 Porphobilinogen synthase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (325 aa)
hemLCOGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015421:IPR005814:IPR015424:IPR004639; KEGG: bbe:BBR47_18060 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: C0ZAH4 Glutamate-1-semialdehyde 2,1-aminomutase 2; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (441 aa)
ADL12143.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
ADL12176.1COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: mac:MA0847 methyltransferase; SPTR: Q8TSF1 Methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (351 aa)
cobTNicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (350 aa)
ADL12365.1precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: cby:CLM_1073 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: C1FVC4 Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase. (205 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (376 aa)
ADL12367.1Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR014777:IPR000878:IPR012818; KEGG: lba:Lebu_0508 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: C7NEQ8 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), [...] (208 aa)
ADL12368.1COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: dae:Dtox_1292 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; SPTR: C6Q7R1 Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Met-10+ like-protein; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit. (196 aa)
ADL12369.1COGs: COG2243 Precorrin-2 methylase; InterPro IPR012382:IPR014777:IPR000878:IPR006364; KEGG: dae:Dtox_1293 precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Cobalt-factor II C(20)-methyltransferase; SPTR: C1TH33 Precorrin-2 C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase. (237 aa)
ADL12370.1COGs: COG2875 Precorrin-4 methylase; InterProIPR003043:IPR014777:IPR014776:IPR000878:IPR 006362; KEGG: amt:Amet_0074 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: A6TJE9 Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase. (254 aa)
ADL12371.1COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: drm:Dred_2710 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: A1HPX3 Cobalamin (Vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal. (353 aa)
ADL12372.1COGs: COG1010 Precorrin-3B methylase; InterPro IPR014777:IPR000878:IPR006363; KEGG: dps:DP0224 precorrin-3B C17-methyltransferase (CobJ); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Q6ARS2 Probable precorrin-3B C17-methyltransferase (CobJ); TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. (273 aa)
ADL12373.1COGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: dae:Dtox_1297 precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; SPTR: C6PHW4 Precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase. (252 aa)
ADL12374.1Adenosylcobinamide-phosphateguanylyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: drm:Dred_1910 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: A4J5S8 Adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. (207 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (505 aa)
cobQ-2Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (506 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (462 aa)
ADL12379.1Cob(I)yrinic acid a,c-diamide adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: hmo:HM1_1898 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: B0TFD9 ATP:corrinoid adenosyltransferase btur/cobo/cobp; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase. (199 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (251 aa)
ADL12381.1GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR012363:IPR006204:IPR013750:IPR020568; KEGG: mta:Moth_1103 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: A1HPW0 GHMP kinase; PFAM: GHMP kinases N terminal domain. (302 aa)
ADL12382.1L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR004838:IPR001176:IPR015421:IPR015422:IPR 004839:IPR015424:IPR005860; KEGG: dae:Dtox_3089 L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: C1TJJ7 L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. (368 aa)
ADL12383.1COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078:IPR017578; KEGG: mta:Moth_1105 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Q2RJH0 Phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase. (203 aa)
ADL12476.1COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dsy:DSY4756 hypothetical protein; SPTR: Q24N47 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). (389 aa)
Your Current Organism:
Acetohalobium arabaticum
NCBI taxonomy Id: 574087
Other names: A. arabaticum DSM 5501, Acetohalobium arabaticum DSM 5501, Acetohalobium arabaticum str. DSM 5501, Acetohalobium arabaticum strain DSM 5501
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