(12 nodes) Thiamine metabolic process, and ThiF family network (Vibrio tasmaniensis)

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	VS_3093	ThiH. (375 aa)
	thiG	ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa)
	VS_3095	ThiS. (69 aa)
	VS_3096	ThiF. (260 aa)
	VS_3097	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (430 aa)
	thiC	ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (649 aa)
	VS_II0489	Molybdopterin biosynthesis protein moeB. (251 aa)
	thiE	Putative thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (228 aa)
	thiM	Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (280 aa)
	VS_II1086	Putative transcriptional activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (222 aa)
	VS_II1090	Phosphomethylpyrimidine kinase. (302 aa)
	VS_II1447	Conserved hypothetical protein. (206 aa)

Your Current Organism:

Vibrio tasmaniensis

NCBI taxonomy Id: 575788
Other names: V. tasmaniensis LGP32, Vibrio lentus MEL32, Vibrio splendidus LGP32, Vibrio tasmaniensis LGP32

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VS_3093	VS_3095	VS_3093	VS_3095	ThiH.	ThiS.	0.983
VS_3093	VS_3096	VS_3093	VS_3096	ThiH.	ThiF.	0.922
VS_3093	VS_3097	VS_3093	VS_3097	ThiH.	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).	0.969
VS_3093	VS_II0489	VS_3093	VS_II0489	ThiH.	Molybdopterin biosynthesis protein moeB.	0.669
VS_3093	VS_II1090	VS_3093	VS_II1090	ThiH.	Phosphomethylpyrimidine kinase.	0.606
VS_3093	thiC	VS_3093	VS_3098	ThiH.	ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.987
VS_3093	thiE	VS_3093	VS_II1083	ThiH.	Putative thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.819
VS_3093	thiG	VS_3093	VS_3094	ThiH.	ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.999
VS_3093	thiM	VS_3093	VS_II1085	ThiH.	Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.	0.575
VS_3095	VS_3093	VS_3095	VS_3093	ThiS.	ThiH.	0.983
VS_3095	VS_3096	VS_3095	VS_3096	ThiS.	ThiF.	0.997
VS_3095	VS_3097	VS_3095	VS_3097	ThiS.	ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).	0.960
VS_3095	VS_II0489	VS_3095	VS_II0489	ThiS.	Molybdopterin biosynthesis protein moeB.	0.983
VS_3095	VS_II1086	VS_3095	VS_II1086	ThiS.	Putative transcriptional activator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.	0.704
VS_3095	VS_II1090	VS_3095	VS_II1090	ThiS.	Phosphomethylpyrimidine kinase.	0.957
VS_3095	thiC	VS_3095	VS_3098	ThiS.	ThiC, thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.971
VS_3095	thiE	VS_3095	VS_II1083	ThiS.	Putative thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.791
VS_3095	thiG	VS_3095	VS_3094	ThiS.	ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.999
VS_3095	thiM	VS_3095	VS_II1085	ThiS.	Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.	0.840
VS_3096	VS_3093	VS_3096	VS_3093	ThiF.	ThiH.	0.922