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| | rnfC-2 | Putative membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (276 aa) |
| | VS_II1468 | Glutathione-dependent formaldehyde-activating, GFA. (138 aa) |
| | VS_II1453 | Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa) |
| | VS_II1447 | Conserved hypothetical protein. (206 aa) |
| | VS_II1280 | Ribosomal subunit interface protein. (118 aa) |
| | VS_II1158 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (399 aa) |
| | VS_II1147 | Conserved hypothetical protein. (155 aa) |
| | VS_II1145 | Putative deoxycytidylate deaminase. (147 aa) |
| | deaD | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (689 aa) |
| | VS_II1030 | Serine-threonine protein kinase. (611 aa) |
| | VS_II0872 | Conserved hypothetical protein. (459 aa) |
| | VS_II0829 | Hypothetical protein. (138 aa) |
| | VS_II0776 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (468 aa) |
| | VS_II0683 | Conserved hypothetical protein. (392 aa) |
| | VS_II0678 | Hypothetical protein. (255 aa) |
| | VS_II0530 | Hypothetical protein. (314 aa) |
| | VS_II0492 | Hypothetical dipeptidase. (498 aa) |
| | VS_II0477 | Putative Flp pilus assembly protein TadD. (376 aa) |
| | rhlE | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (523 aa) |
| | VS_II0299 | Hypothetical protein. (160 aa) |
| | VS_II0210 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (563 aa) |
| | VS_II0200 | ATP-dependent RNA helicase, DEAD box family; Function of homologous gene experimentally demonstrated in another organism; enzyme; Belongs to the DEAD box helicase family. (447 aa) |
| | VS_II0027 | Conserved hypothetical protein. (324 aa) |
| | VS_II0002 | ParB family protein; Belongs to the ParB family. (324 aa) |
| | VS_3160 | ParB family protein; Belongs to the ParB family. (293 aa) |
| | VS_3122 | Hypothetical protein. (189 aa) |
| | VS_3077 | RecQ. (612 aa) |
| | rplK | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (162 aa) |
| | rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | rplJ | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (177 aa) |
| | rplL | Putative ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa) |
| | VS_2954 | DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (110 aa) |
| | fis | Putative factor-for-inversion stimulation protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (733 aa) |
| | rpmE | Ribosomal protein L31; Binds the 23S rRNA. (72 aa) |
| | rpsG | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (108 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rplD | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (200 aa) |
| | rplW | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa) |
| | rplV | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (111 aa) |
| | rpsC | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (64 aa) |
| | rpsQ | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (98 aa) |
| | rplX | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (105 aa) |
| | rplE | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (177 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (166 aa) |
| | rpmD | Ribosomal protein L30. (67 aa) |
| | rplO | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpsK | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsD | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rplQ | Ribosomal protein L17. (126 aa) |
| | VS_2731 | DNA polymerase III chi subunit. (149 aa) |
| | recO | DNA repair protein recO; Involved in DNA repair and RecF pathway recombination. (242 aa) |
| | rpsP | Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | VS_2518 | iron(III) ABC transporter, periplasmic iron-compound-binding protein. (338 aa) |
| | infB | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (896 aa) |
| | rpsO | Similar to ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | VS_2450 | Long-chain acyl-CoA synthetase. (562 aa) |
| | VS_2434 | TPR-repeat-containing protein. (334 aa) |
| | rpmE2 | Ribosomal protein L31. (86 aa) |
| | rpsB | Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (254 aa) |
| | dnaQ | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (255 aa) |
| | VS_2280 | Protein ybbN. (284 aa) |
| | VS_2201 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (97 aa) |
| | VS_2057 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (556 aa) |
| | ihfB | Integration host factor beta-subunit (IHF-beta); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (94 aa) |
| | VS_2044 | Hypothetical protein. (451 aa) |
| | VS_1905 | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (410 aa) |
| | VS_1868 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (147 aa) |
| | rplY | Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (92 aa) |
| | tfoX | DNA transformation protein; Function of homologous gene experimentally demonstrated in another organism; putative factor. (193 aa) |
| | VS_1735 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) |
| | ihfA | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (98 aa) |
| | VS_1678 | Tfp pilus assembly protein PilF. (249 aa) |
| | VS_1655 | Putative DNA repair protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0758 family. (156 aa) |
| | VS_1650 | Putative Helicase IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (961 aa) |
| | VS_1648 | Putative RNA polymerase-associated protein rapA (ATP-dependent helicase hepA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1044 aa) |
| | VS_1606 | SAM-dependent methyltransferase. (198 aa) |
| | VS_1599 | Conserved hypothetical protein. (137 aa) |
| | VS_1532 | Putative polysaccharide export protein. (474 aa) |
| | cobB | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. (244 aa) |
| | VS_1439 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (247 aa) |
| | matP | Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (151 aa) |
| | VS_1281 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (160 aa) |
| | rpmI | 50S ribosomal protein L35; Function of homologous gene experimentally demonstrated in another organism; structure; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | VS_1115 | tolA protein. (319 aa) |
| | VS_1087 | Hypothetical protein. (196 aa) |
| | VS_1065 | Primosomal replication protein N''. (196 aa) |
| | rpmF | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (56 aa) |
| | rnfC | Electron transport complex protein RnfC (fragment); Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (663 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | topB | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (663 aa) |
| | recR | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa) |
| | VS_0917 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (109 aa) |
| | VS_0703 | ATP-dependent DNA helicase recQ. (644 aa) |
| | VS_0683 | Probable cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (403 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (381 aa) |
| | VS_0646 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (554 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | cutC | Copper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (247 aa) |
| | VS_0557 | Putative sigma-54 modulation protein. (111 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa) |
| | VS_0530 | nptA protein. (406 aa) |
| | srmB | ATP-dependent RNA helicase srmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (421 aa) |
| | VS_0435 | SspB. (164 aa) |
| | rpsI | Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rpsU | Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (583 aa) |
| | rpmA | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | VS_0341 | Rod shape-determining protein mreB. (347 aa) |
| | VS_0284 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (463 aa) |
| | rplI | Ribosomal protein L9; Binds to the 23S rRNA. (150 aa) |
| | rpsR | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rpsF | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (137 aa) |
| | rpmG | Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | rpmB | Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | VS_0182 | DNA repair protein radC homolog; Belongs to the UPF0758 family. (224 aa) |
| | slmA | HTH-type protein slmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. (196 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (144 aa) |
| | rep | ATP-dependent DNA helicase rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (672 aa) |
| | VS_0025 | Conserved hypothetical protein, TadD; Homologs of previously reported genes of unknown function. (260 aa) |
| | recF | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (359 aa) |
| | dnaA | Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (473 aa) |
| | rpmH | Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
