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| | ftsE | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (225 aa) |
| | coaA | Pantothenate kinase. (307 aa) |
| | tuf-2 | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (412 aa) |
| | hslU | ATP-dependent hsl protease ATP-binding subunit hslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (446 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (733 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa) |
| | VS_2870 | Hypothetical protein. (505 aa) |
| | VS_2854 | Phosphoribulokinase. (289 aa) |
| | VS_2850 | ABC transporter, ATP-binding protein. (640 aa) |
| | fusA-2 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (698 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | cysN | Sulfate adenylate transferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (476 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (206 aa) |
| | VS_2782 | ABC transporter nucleotide-binding domain. (230 aa) |
| | thiQ | Thiamine transport ATP-binding protein thiQ; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (235 aa) |
| | VS_2760 | Hypothetical protein; Displays ATPase and GTPase activities. (289 aa) |
| | VS_1650 | Putative Helicase IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (961 aa) |
| | VS_II0401 | ABC transporter: ATP-binding protein; Belongs to the ABC transporter superfamily. (369 aa) |
| | VS_II0408 | Thermoresistant gluconokinase. (165 aa) |
| | VS_II0421 | ABC transport system, Transmembrane and ATP-binding site (ABC-IM). (587 aa) |
| | VS_II0422 | Hypothetical ABC transporter ATP-binding protein. (594 aa) |
| | VS_II0461 | Helicase IV. (691 aa) |
| | VS_II0473 | Putative Flp pilus assembly protein TadZ. (397 aa) |
| | VS_II0474 | Putative Flp pilus assembly protein TadA. (421 aa) |
| | VS_II0498 | ABC transporter: ATP-binding protein. (261 aa) |
| | VS_II0509 | ABC transporter: Transmembrane and ATP-binding protein. (548 aa) |
| | VS_II0510 | ABC transporter: Transmembrane and ATP-binding protein. (750 aa) |
| | VS_II0534 | ABC transporter: ATP binding protein. (248 aa) |
| | VS_II0563 | Anaerobic nitric oxide reductase transcription regulator. (530 aa) |
| | VS_II0567 | Putative cobalamin synthesis protein. (327 aa) |
| | VS_II0568 | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (428 aa) |
| | VS_II0612 | Putative GTPase. (343 aa) |
| | VS_II0640 | Putative ATPase. (551 aa) |
| | VS_II0691 | ABC transporter: ATP-binding protein. (244 aa) |
| | VS_II0718 | Hypothetical ABC transporter ATP-binding protein. (527 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (488 aa) |
| | modC | Molybdenum import ATP-binding protein modC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (385 aa) |
| | VS_II0758 | ABC transporter, ATP-binding protein. (224 aa) |
| | VS_II0762 | Hypothetical protein. (557 aa) |
| | VS_II0776 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (468 aa) |
| | VS_II0784 | Predicted ATP-dependent endonuclease. (590 aa) |
| | VS_II0799 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (423 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (582 aa) |
| | VS_II0832 | ABC transporter, ATP-binding protein-related protein. (533 aa) |
| | VS_II0861 | ABC transporter, transmembrane protein-ATP-binding protein (IM, ABC). (528 aa) |
| | VS_II0862 | ABC transporter (IM-ABC). (712 aa) |
| | VS_II0877 | MoxR-like ATPase. (327 aa) |
| | atpA-2 | ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpD-2 | ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (461 aa) |
| | VS_II0932 | ABC transporter: two domain ATP-binding protein; Belongs to the ABC transporter superfamily. (549 aa) |
| | rbsA | ABC transporter: two domain ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa) |
| | VS_II1006 | Chaperone ClpB; Function of homologous gene experimentally demonstrated in another organism; factor; Belongs to the ClpA/ClpB family. (897 aa) |
| | vasH | Sigma 54 dependant transcriptional regulator; Function of homologous gene experimentally demonstrated in another organism; regulator. (542 aa) |
| | VS_II1067 | ABC transporter, ATP-binding protein; Function of homologous gene experimentally demonstrated in another organism; transporter. (254 aa) |
| | VS_II1089 | ABC transporter: ATP binding protein. (252 aa) |
| | VS_II1123 | ABC transporter: ATP-binding protein; Function of homologous gene experimentally demonstrated in another organism; transporter. (257 aa) |
| | deaD | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (689 aa) |
| | VS_II1158 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (399 aa) |
| | VS_II1163 | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (468 aa) |
| | VS_II1188 | Hypothetical ABC transporter ATP-binding protein. (284 aa) |
| | ugpC | ABC-type sugar transport systems, ATPase components; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (396 aa) |
| | VS_II1268 | ABC transporter: ATP-binding protein. (486 aa) |
| | phnC | ABC transporter: ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (256 aa) |
| | VS_II1288 | Two component, sigma54 specific, transcriptional regulator, Fis family. (450 aa) |
| | VS_II1295 | Conserved hypothetical protein. (335 aa) |
| | VS_II1336 | Sigma-54 dependent transcriptional regulator. (595 aa) |
| | VS_II1375 | ATP-dependent protease LA-related. (786 aa) |
| | VS_II1377 | ABC transporter: ATP-binding protein; Belongs to the ABC transporter superfamily. (542 aa) |
| | VS_II1387 | ABC-type sugar transport system, ATP-binding protein; Belongs to the ABC transporter superfamily. (363 aa) |
| | VS_II1492 | ABC transporter: ATP-binding protein. (237 aa) |
| | VS_II1528 | ABC systems: ATP binding protein. (277 aa) |
| | VS_II1529 | ABC systems: ATP-binding protein; Belongs to the ABC transporter superfamily. (310 aa) |
| | VS_1676 | Hypothetical protein. (122 aa) |
| | btuD | Putative vitamin B12 ABC transporter,ATP-binding protein BtuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (252 aa) |
| | VS_1700 | Similar to cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (205 aa) |
| | VS_1775 | ATP-dependent helicase. (1355 aa) |
| | VS_1793 | Transcriptional regulatory protein tyrR. (514 aa) |
| | VS_1848 | ABC transporter: ATP-binding protein. (227 aa) |
| | VS_1854 | Helicase-related protein. (579 aa) |
| | VS_1903 | Probable ATP-dependent transporter sufC. (248 aa) |
| | VS_1992 | Psp operon transcriptional activator. (340 aa) |
| | VS_1996 | Peptide transport system ATP-binding protein sapD; Belongs to the ABC transporter superfamily. (333 aa) |
| | VS_1997 | Peptide transport system ATP-binding protein sapF. (260 aa) |
| | tdk | Thymidine kinase. (192 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (234 aa) |
| | VS_2044 | Hypothetical protein. (451 aa) |
| | VS_2046 | DNA translocase ftsK. (1045 aa) |
| | cmk | Cytidylate kinase. (226 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (335 aa) |
| | msbA | Transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (589 aa) |
| | lolD | Lipoprotein-releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (230 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1153 aa) |
| | VS_2112 | Ferrichrome transport ATP-binding protein fhuC. (255 aa) |
| | lon | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (783 aa) |
| | VS_2141 | Transcriptional regulator. (447 aa) |
| | clpX | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (426 aa) |
| | VS_2208 | dctD, C4-dicarboxylate transport transcriptional regulatory protein. (449 aa) |
| | VS_2226 | Probable ATP-dependent helicase. (642 aa) |
| | VS_2233 | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (757 aa) |
| | znuC | znuC, High-affinity zinc uptake system ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (259 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | metN | D-methionine transport ATP-binding protein metN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (344 aa) |
| | VS_2437 | Flp pilus assembly protein. (484 aa) |
| | VS_2438 | Flp pilus assembly protein. (404 aa) |
| | VS_2445 | Predicted ATPase with chaperone activity. (449 aa) |
| | fusA | Elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (695 aa) |
| | radA | Predicted ATP-dependent serine protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (459 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa) |
| | infB | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (896 aa) |
| | ftsH | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (659 aa) |
| | VS_2509 | Oligopeptide transport ATP-binding protein oppD; Belongs to the ABC transporter superfamily. (327 aa) |
| | VS_2510 | Peptide ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (331 aa) |
| | VS_2516 | ABC-type spermidine/putrescine transport system, ATPase component; Belongs to the ABC transporter superfamily. (342 aa) |
| | VS_2526 | Helicase. (832 aa) |
| | VS_2535 | Hypothetical ABC transporter ATP-binding protein. (305 aa) |
| | pilB | Type IV pilin assembly protein; Function of homologous gene experimentally demonstrated in another organism; putative membrane component. (564 aa) |
| | VS_2551 | Dephospho-CoA kinase; Function of strongly homologous gene; putative enzyme; Belongs to the CoaE family. (88 aa) |
| | VS_2552 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoaE family. (84 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (470 aa) |
| | VS_2586 | ABC transporter; Belongs to the ABC transporter superfamily. (373 aa) |
| | recA | Protein recA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (350 aa) |
| | mutS | DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa) |
| | pyrG | CTP synthase (UTP--ammonia ligase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | era | GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (323 aa) |
| | lepA | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (597 aa) |
| | VS_2656 | Iron ABC transporter, ATP-binding protein. (252 aa) |
| | cbiA | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (434 aa) |
| | VS_2681 | Tfp pilus assembly protein. (372 aa) |
| | VS_2682 | Tfp pilus assembly protein. (345 aa) |
| | VS_2750 | ABC transporter: ATP-binding protein. (279 aa) |
| | VS_2756 | Probable ABC transporter ATP-binding protein. (241 aa) |
| | VS_1646 | Putative helicase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1345 aa) |
| | VS_1643 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (559 aa) |
| | purA-2 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa) |
| | VS_1625 | Nuclease sbcCD subunit C. (1240 aa) |
| | VS_1565 | ABC transporter: transmembrane and ATP binding protein. (611 aa) |
| | VS_1564 | ABC transporter: ATP-binding protein. (247 aa) |
| | VS_1527 | Putative LuxO repressor protein. (503 aa) |
| | VS_1525 | ABC transporter: ATP binding protein. (410 aa) |
| | VS_1522 | Putative capsular polysaccharide biosynthesis protein. (229 aa) |
| | VS_1503 | Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (605 aa) |
| | VS_1501 | ABC transporter, ATP-binding protein. (239 aa) |
| | VS_1498 | Sigma-54 dependent response regulator. (509 aa) |
| | VS_1495 | Hypothetical protein. (781 aa) |
| | VS_1494 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (293 aa) |
| | VS_1493 | Putative transporter fused subunits of ABC superfamily: ATP-binding components (fragment). (207 aa) |
| | potA | Spermidine/putrescine import ATP-binding protein potA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (371 aa) |
| | VS_1430 | Putative protease La homolog. (550 aa) |
| | VS_1426 | ABC transporter ATP-binding protein. (638 aa) |
| | VS_1414 | ATP-binding/permease protein. (598 aa) |
| | VS_1400 | General L-amino acid transport ATP-binding protein. (254 aa) |
| | VS_1385 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (2085 aa) |
| | VS_1381 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (913 aa) |
| | hsdR | Type I restriction enzyme EcoKI, R subunit; Function of homologous gene experimentally demonstrated in another organism; enzyme. (1187 aa) |
| | VS_1359 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (459 aa) |
| | VS_1326 | Putative protein disaggregation chaperone (clpB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the ClpA/ClpB family. (870 aa) |
| | VS_1261 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (566 aa) |
| | VS_1260 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (376 aa) |
| | VS_1235 | Putative ABC-type transport system, ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (524 aa) |
| | VS_1225 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (645 aa) |
| | VS_1206 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (174 aa) |
| | VS_1203 | Putative ATP-dependent helicase. (794 aa) |
| | VS_1190 | Hypothetical protein. (1067 aa) |
| | VS_1185 | Transport ATP-binding protein cydD. (594 aa) |
| | VS_1184 | Transport ATP-binding protein cydC. (573 aa) |
| | VS_1179 | ABC-type proline/glycine betaine transport system, ATPase component. (395 aa) |
| | VS_1172 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (418 aa) |
| | VS_1162 | Putative ABC transporter, ATP-binding protein. (216 aa) |
| | viuC | ABC transporter: ATP-binding protein; Function of homologous gene experimentally demonstrated in another organism; transporter. (270 aa) |
| | ruvB | Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (338 aa) |
| | VS_1096 | Chromosome partition protein mukB; Belongs to the SMC family. MukB subfamily. (1484 aa) |
| | VS_1074 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (757 aa) |
| | dinG | Probable ATP-dependent helicase dinG; DNA-dependent ATPase and 5'-3' DNA helicase. (703 aa) |
| | VS_1054 | Histidine transport ATP-binding protein hisP. (256 aa) |
| | VS_1047 | PrkA serine protein kinase. (646 aa) |
| | VS_1042 | Hypothetical protein. (235 aa) |
| | VS_1030 | DNA polymerase III delta' subunit. (321 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa) |
| | VS_1013 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (222 aa) |
| | udk | Uridine kinase. (213 aa) |
| | VS_1010 | Mrp protein homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (358 aa) |
| | VS_0997 | Phosphate acetyltransferase. (734 aa) |
| | VS_0994 | Oligopeptide transport ATP-binding protein oppF; Belongs to the ABC transporter superfamily. (331 aa) |
| | VS_0993 | Oligopeptide transport ATP-binding protein oppD; Belongs to the ABC transporter superfamily. (323 aa) |
| | VS_0982 | LuxO repressor protein. (448 aa) |
| | uvrB | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (676 aa) |
| | dnaX | DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (752 aa) |
| | VS_0882 | Septum site-determining protein minD (Cell division inhibitor minD). (270 aa) |
| | hflX-2 | Probable GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (455 aa) |
| | VS_0878 | ABC transporter: ATP-binding protein; Belongs to the ABC transporter superfamily. (370 aa) |
| | ccmA | Cytochrome c biogenesis ATP-binding export protein ccmA (heme exporter protein A); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa) |
| | VS_0845 | SOJ-like and chromosome partitioning protein. (260 aa) |
| | VS_0839 | Flagellar biosynthesis protein FlhG. (295 aa) |
| | VS_0838 | Flagellar biosynthesis protein flhF. (503 aa) |
| | VS_0826 | Flagellum-specific ATP synthase. (439 aa) |
| | VS_0821 | FlaM. (469 aa) |
| | VS_0819 | Polar flagellar protein FlaK. (487 aa) |
| | ychF | GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (383 aa) |
| | VS_0723 | PhoH-like protein. (373 aa) |
| | VS_0716 | DNA polymerase III, delta subunit. (341 aa) |
| | VS_0703 | ATP-dependent DNA helicase recQ. (644 aa) |
| | recD | Putative Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] (741 aa) |
| | recB | Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...] (1224 aa) |
| | recC | Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...] (1158 aa) |
| | VS_0646 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (554 aa) |
| | der | GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (493 aa) |
| | pstB | ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (272 aa) |
| | clpB | Chaperone clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa) |
| | VS_0551 | ABC transporter ATP-binding protein. (555 aa) |
| | VS_0518 | Sigma-54 dependent transcriptional regulator. (444 aa) |
| | srmB | ATP-dependent RNA helicase srmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (421 aa) |
| | secA | Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (908 aa) |
| | zapE | Hypothetical protein; Reduces the stability of FtsZ polymers in the presence of ATP. (367 aa) |
| | VS_0408 | Putative general secretion pathway protein A. (556 aa) |
| | obg | GTP1/Obg family protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa) |
| | rapA | RNA polymerase associated protein rapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (969 aa) |
| | VS_0349 | Hypothetical protein. (472 aa) |
| | VS_0331 | MSHA biogenesis protein MshE. (574 aa) |
| | VS_0329 | MSHA biogenesis protein MshM. (279 aa) |
| | uvrA | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | VS_0284 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (463 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (438 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (435 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (310 aa) |
| | VS_0266 | Hypothetical protein. (182 aa) |
| | rsgA | Probable GTPase engC protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (351 aa) |
| | VS_0215 | Putative tyrosine-protein kinase (wzc); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (722 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | recG | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (696 aa) |
| | VS_0136 | Type II secretory pathway, ATPase EpsE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (500 aa) |
| | VS_0124 | Conserved hypothetical protein. (176 aa) |
| | VS_0123 | GTP-binding protein typA/bipA. (610 aa) |
| | ntrC | Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (467 aa) |
| | engB | Probable GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (269 aa) |
| | VS_0074 | Hypothetical ABC transporter ATP-binding protein. (575 aa) |
| | rep | ATP-dependent DNA helicase rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (672 aa) |
| | VS_0022 | Putative bacterial type II secretion system protein E, TadA, CpaF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (427 aa) |
| | VS_0021 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (407 aa) |
| | recF | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (359 aa) |
| | dnaA | Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (473 aa) |
| | VS_0007 | Probable amino-acid ABC transporter ATP-binding protein. (245 aa) |
| | mnmE | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (467 aa) |
| | rhlE | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (523 aa) |
| | hmuV | Hemin ABC transporter, ATP-binding protein HutD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (260 aa) |
| | VS_II0247 | ABC transporter: ATP binding protein. (237 aa) |
| | malK | ABC transporter: ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (370 aa) |
| | VS_II0215 | Putative MoxR-ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (318 aa) |
| | pstB-2 | ABC transporter: ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (249 aa) |
| | VS_II0200 | ATP-dependent RNA helicase, DEAD box family; Function of homologous gene experimentally demonstrated in another organism; enzyme; Belongs to the DEAD box helicase family. (447 aa) |
| | VS_II0188 | ABC transporter: two domain ATP-binding protein; Function of strongly homologous gene; transporter. (564 aa) |
| | malT | HTH-type transcriptional regulator malT (ATP-dependent transcriptional activator malT); Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (907 aa) |
| | rsgA-2 | Putative GTPase (eng C); One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (354 aa) |
| | VS_II0166 | Hypothetical protein. (1662 aa) |
| | VS_II0061 | ABC transporter: ATP binding protein. (395 aa) |
| | VS_II0026 | ABC transporters: Transmembrane and ATP-binding protein. (616 aa) |
| | VS_II0009 | Putative two-component response regulator. (437 aa) |
| | VS_II0005 | ABC transporter IM-ABC: Transmembrane and ATP binding protein. (704 aa) |
| | tmcA | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (710 aa) |
| | VS_II0001 | ParA family protein. (405 aa) |
| | VS_3161 | ParA family protein. (257 aa) |
| | VS_1648 | Putative RNA polymerase-associated protein rapA (ATP-dependent helicase hepA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1044 aa) |
| | atpA | ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (523 aa) |
| | atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (467 aa) |
| | VS_3142 | Competence protein comM. (507 aa) |
| | VS_3084 | DNA helicase II. (724 aa) |
| | VS_3077 | RecQ. (612 aa) |
| | rhlB | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (436 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (427 aa) |
| | ftsY | Cell division protein ftsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (422 aa) |
