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VS_2244 VS_2244 VS_2242 VS_2242 sucC sucC sucD sucD VS_1797 VS_1797 VS_1071 VS_1071 mdh mdh VS_0248 VS_0248 VS_0247 VS_0247 frdC frdC frdD frdD pckA pckA fumC fumC VS_2881 VS_2881 VS_2629 VS_2629 VS_2542 VS_2542 VS_2541 VS_2541 VS_2540 VS_2540 VS_2522 VS_2522 VS_2249 VS_2249 VS_2248 VS_2248 VS_2247 VS_2247 VS_2246 VS_2246 VS_2243 VS_2243
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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VS_2244Succinate dehydrogenase; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa)
VS_2242Dihydrolipoyllysine-residue succinyltransferase (component of 2-oxoglutaratedehydrogenase complex); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (401 aa)
sucCSuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDSuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
VS_1797Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (561 aa)
VS_1071Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
VS_0248Fumarate reductase flavoprotein subunit. (607 aa)
VS_0247Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (254 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa)
frdDFumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (145 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (541 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
VS_2881Dihydrolipoyl dehydrogenase. (488 aa)
VS_2629Hypothetical protein. (86 aa)
VS_2542Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
VS_2541Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (624 aa)
VS_2540Dihydrolipoyl dehydrogenase. (476 aa)
VS_2522Aconitate hydratase 2 (Citrate hydro-lyase 2); Belongs to the aconitase/IPM isomerase family. (871 aa)
VS_2249Citrate synthase; Belongs to the citrate synthase family. (429 aa)
VS_2248Succinate dehydrogenase cytochrome. (130 aa)
VS_2247Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
VS_2246Putative succinate dehydrogenase, flavoprotein subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (552 aa)
VS_22432-oxoglutarate dehydrogenase E1 component. (939 aa)
Your Current Organism:
Vibrio tasmaniensis
NCBI taxonomy Id: 575788
Other names: V. tasmaniensis LGP32, Vibrio lentus MEL32, Vibrio splendidus LGP32, Vibrio tasmaniensis LGP32
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