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cobQ cobQ VS_II0671 VS_II0671 VS_II0640 VS_II0640 VS_II0623 VS_II0623 cyoE cyoE VS_II0371 VS_II0371 VS_II0291 VS_II0291 VS_II0290 VS_II0290 VS_II0252 VS_II0252 VS_II0215 VS_II0215 hemF hemF VS_3054 VS_3054 VS_3053 VS_3053 hemC hemC VS_2664 VS_2664 VS_2665 VS_2665 VS_2666 VS_2666 VS_2667 VS_2667 VS_2668 VS_2668 VS_2670 VS_2670 cobD cobD cbiA cbiA VS_2689 VS_2689 hemE hemE cyaY cyaY VS_0044 VS_0044 VS_0091 VS_0091 VS_0105 VS_0105 VS_0116 VS_0116 VS_0467 VS_0467 VS_0636 VS_0636 rlmG rlmG hemA hemA gltX gltX VS_1013 VS_1013 cmoB cmoB VS_1141 VS_1141 VS_1404 VS_1404 VS_1699 VS_1699 VS_1700 VS_1700 cobS cobS cobT cobT VS_1704 VS_1704 VS_1783 VS_1783 VS_1850 VS_1850 tig tig hemH hemH map map VS_2375 VS_2375 hemL hemL rsmC rsmC gluQ gluQ cbiD cbiD VS_2662 VS_2662 VS_2663 VS_2663 VS_II1453 VS_II1453 VS_II0877 VS_II0877 VS_II0868 VS_II0868
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (488 aa)
VS_II0671Uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (258 aa)
VS_II0640Putative ATPase. (551 aa)
VS_II0623Transcription activator ToxR. (241 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (324 aa)
VS_II0371Putative cytochrome c oxidase assembly protein. (340 aa)
VS_II0291Hypothetical protein. (173 aa)
VS_II0290Oxygen-independent coproporphyrinogen III oxidase. (469 aa)
VS_II0252Radical SAM. (403 aa)
VS_II0215Putative MoxR-ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (318 aa)
hemFCoproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (305 aa)
VS_3054Membrane protein HemX. (412 aa)
VS_3053Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (242 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (312 aa)
VS_2664Precorrin-2 C-20 methlytransferase; Belongs to the precorrin methyltransferase family. (271 aa)
VS_2665Cobalamin biosynthesis protein. (534 aa)
VS_2666Putative cobalt chelatase. (280 aa)
VS_2667Precorrin-3B methylase CobJ. (279 aa)
VS_2668Precorrin-3 methylase. (270 aa)
VS_2670Cobalamin biosynthetic protein CobC. (356 aa)
cobDCobalamin biosynthesis protein CobD/CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
cbiACobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (434 aa)
VS_2689Oxygen-independent coproporphyrinogen III oxidase-like protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (395 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (373 aa)
cyaYProtein cyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (104 aa)
VS_0044Flavodoxin. (175 aa)
VS_0091Ferritin-like protein; Iron-storage protein. (175 aa)
VS_0105Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (347 aa)
VS_0116Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (463 aa)
VS_0467Cobalamin biosynthesis protein. (317 aa)
VS_0636Conserved hypothetical protein. (312 aa)
rlmGPutative ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (383 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (419 aa)
gltXGlutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (475 aa)
VS_1013Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (222 aa)
cmoBConserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (323 aa)
VS_1141Hypothetical protein. (792 aa)
VS_1404Uroporphyrin-III C-methyltransferase. (313 aa)
VS_1699Fructose-2,6-bisphosphatase. (205 aa)
VS_1700Similar to cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (205 aa)
cobSCobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (268 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (342 aa)
VS_1704Hypothetical protein. (231 aa)
VS_1783Hypothetical protein. (118 aa)
VS_1850Putative nucleoside-diphosphate-sugar epimerase. (478 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (432 aa)
hemHFerrochelatase (Protoheme ferro-lyase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (320 aa)
mapMethionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (292 aa)
VS_2375Conserved hypothetical protein. (521 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (431 aa)
rsmC16S RNA methylase RsmC; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (340 aa)
gluQGlutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (300 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (394 aa)
VS_2662Precorrin-8X methylmutase CbiC. (219 aa)
VS_2663Precorrin-6y methylase. (432 aa)
VS_II1453Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa)
VS_II0877MoxR-like ATPase. (327 aa)
VS_II0868Arylsulfatase regulator. (443 aa)
Your Current Organism:
Vibrio tasmaniensis
NCBI taxonomy Id: 575788
Other names: V. tasmaniensis LGP32, Vibrio lentus MEL32, Vibrio splendidus LGP32, Vibrio tasmaniensis LGP32
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