STRINGSTRING
VS_II0294 VS_II0294 VS_0011 VS_0011 rep rep mutL mutL VS_0323 VS_0323 surA surA VS_0514 VS_0514 mutH mutH xseA xseA VS_0634 VS_0634 VS_0716 VS_0716 dnaX dnaX VS_0961 VS_0961 rnt rnt VS_1030 VS_1030 dnaE2 dnaE2 VS_1253 VS_1253 VS_1518 VS_1518 VS_1635 VS_1635 VS_1713 VS_1713 VS_1822 VS_1822 VS_2200 VS_2200 ligA ligA dnaQ dnaQ VS_2337 VS_2337 xseB xseB VS_2469 VS_2469 mutS mutS VS_2731 VS_2731 VS_2869 VS_2869 VS_2918 VS_2918 VS_2941 VS_2941 lexA lexA VS_3084 VS_3084 VS_II0376 VS_II0376 VS_II0461 VS_II0461 VS_II1160 VS_II1160 VS_II1505 VS_II1505
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VS_II0294Peptidyl-prolyl cis-trans isomerase C. (92 aa)
VS_0011DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
repATP-dependent DNA helicase rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (672 aa)
mutLDNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (723 aa)
VS_0323Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (185 aa)
surAPutative Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (431 aa)
VS_0514Single-stranded-DNA-specific exonuclease recJ. (578 aa)
mutHDNA mismatch repair protein mutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (237 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (492 aa)
VS_0634Predicted exonuclease of the beta-lactamase fold involved in RNA processing. (456 aa)
VS_0716DNA polymerase III, delta subunit. (341 aa)
dnaXDNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (752 aa)
VS_0961Superoxide dismutase [Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (194 aa)
rntRibonuclease T (RNase T); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (241 aa)
VS_1030DNA polymerase III delta' subunit. (321 aa)
dnaE2Putative DNA polymerase III alpha chain; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1030 aa)
VS_1253Putative exonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (238 aa)
VS_1518ATP-dependent DNA ligase. (292 aa)
VS_1635Acetyltransferase. (332 aa)
VS_1713Exodeoxyribonuclease I. (474 aa)
VS_1822DNA polymerase III polC-type. (238 aa)
VS_2200Peptidyl-prolyl cis-trans isomerase D. (621 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (670 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (255 aa)
VS_2337DNA polymerase III alpha subunit. (1159 aa)
xseBProbable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
VS_2469Similar to DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (132 aa)
mutSDNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa)
VS_2731DNA polymerase III chi subunit. (149 aa)
VS_2869DNA adenine methylase. (286 aa)
VS_2918Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (205 aa)
VS_2941Putative DNA polymerase III, epsilon subunit. (210 aa)
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (206 aa)
VS_3084DNA helicase II. (724 aa)
VS_II0376Hypothetical protein. (72 aa)
VS_II0461Helicase IV. (691 aa)
VS_II1160DNA polymerase III, alpha subunit. (207 aa)
VS_II1505Hypothetical protein. (88 aa)
Your Current Organism:
Vibrio tasmaniensis
NCBI taxonomy Id: 575788
Other names: V. tasmaniensis LGP32, Vibrio lentus MEL32, Vibrio splendidus LGP32, Vibrio tasmaniensis LGP32
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