(22 nodes) RNA polymerase II transcription regulator complex network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	trf1	TATA-box-binding protein-like protein 1; TATA box-binding transcription factor. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. (216 aa)
	EHI_142760	Protein kinase domain containing protein. (297 aa)
	EHI_106700	Protein kinase domain containing protein. (236 aa)
	183.t00017	Uncharacterized protein. (284 aa)
	35.t00002	TFIIH basal transcription factor complex subunit, putative. (363 aa)
	39.t00053	Transcription initiation factor TFIID subunit 5, putative. (360 aa)
	taf1	Bromodomain protein, putative. (1163 aa)
	68.t00035	Uncharacterized protein. (120 aa)
	7.t00062	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (484 aa)
	133.t00016	Uncharacterized protein. (466 aa)
	40.t00010	DNA repair helicase, putative. (589 aa)
	113.t00005	TFIID subunit, putative. (174 aa)
	115.t00027	TATA-box-binding protein 2; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (212 aa)
	197.t00012	DNA repair helicase, putative. (770 aa)
	297.t00005	DNA repair helicase, putative. (788 aa)
	222.t00013	TFIID subunit, putative. (433 aa)
	222.t00004	Uncharacterized protein. (263 aa)
	292.t00013	Uncharacterized protein. (946 aa)
	281.t00001	DNA repair helicase, putative. (648 aa)
	14.t00057	Uncharacterized protein. (194 aa)
	217.t00008	Cell division protein kinase, putative. (268 aa)
	TBP	TATA-box-binding protein 1; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (234 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
113.t00005	115.t00027	C4M5Y7	C4M7H7	TFIID subunit, putative.	TATA-box-binding protein 2; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.	0.938
113.t00005	133.t00016	C4M5Y7	C4M2J0	TFIID subunit, putative.	Uncharacterized protein.	0.835
113.t00005	14.t00057	C4M5Y7	C4MB87	TFIID subunit, putative.	Uncharacterized protein.	0.999
113.t00005	183.t00017	C4M5Y7	C4LTW8	TFIID subunit, putative.	Uncharacterized protein.	0.945
113.t00005	197.t00012	C4M5Y7	C4M8K7	TFIID subunit, putative.	DNA repair helicase, putative.	0.723
113.t00005	217.t00008	C4M5Y7	C4MBT6	TFIID subunit, putative.	Cell division protein kinase, putative.	0.713
113.t00005	222.t00004	C4M5Y7	C4M9E2	TFIID subunit, putative.	Uncharacterized protein.	0.842
113.t00005	222.t00013	C4M5Y7	C4M9D5	TFIID subunit, putative.	TFIID subunit, putative.	0.999
113.t00005	281.t00001	C4M5Y7	C4MA19	TFIID subunit, putative.	DNA repair helicase, putative.	0.730
113.t00005	292.t00013	C4M5Y7	C4M9U3	TFIID subunit, putative.	Uncharacterized protein.	0.999
113.t00005	297.t00005	C4M5Y7	C4M8Q4	TFIID subunit, putative.	DNA repair helicase, putative.	0.719
113.t00005	35.t00002	C4M5Y7	C4LV67	TFIID subunit, putative.	TFIIH basal transcription factor complex subunit, putative.	0.815
113.t00005	39.t00053	C4M5Y7	C4LWU2	TFIID subunit, putative.	Transcription initiation factor TFIID subunit 5, putative.	0.999
113.t00005	40.t00010	C4M5Y7	C4M2T5	TFIID subunit, putative.	DNA repair helicase, putative.	0.730
113.t00005	68.t00035	C4M5Y7	C4M132	TFIID subunit, putative.	Uncharacterized protein.	0.999
113.t00005	7.t00062	C4M5Y7	C4M1G0	TFIID subunit, putative.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.826
113.t00005	EHI_106700	C4M5Y7	B1N5B0	TFIID subunit, putative.	Protein kinase domain containing protein.	0.713
113.t00005	EHI_142760	C4M5Y7	B1N3Y1	TFIID subunit, putative.	Protein kinase domain containing protein.	0.713
113.t00005	TBP	C4M5Y7	P52653	TFIID subunit, putative.	TATA-box-binding protein 1; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.	0.969
113.t00005	taf1	C4M5Y7	C4LYG8	TFIID subunit, putative.	Bromodomain protein, putative.	0.999