(6 nodes) HSP90, C-terminal domain, and Hsp90 protein binding network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	25.t00027	TPR repeat protein. (564 aa)
	92.t00009	Heat shock protein 90, putative. (718 aa)
	18.t00071	Uncharacterized protein. (187 aa)
	76.t00021	Aha1 domain protein, putative. (131 aa)
	256.t00015	90 kDa heat shock protein, putative. (711 aa)
	92.t00037	Heat shock protein 90, putative. (718 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
18.t00071	25.t00027	C4LYW6	C4LUP1	Uncharacterized protein.	TPR repeat protein.	0.795
18.t00071	256.t00015	C4LYW6	C4M3S9	Uncharacterized protein.	90 kDa heat shock protein, putative.	0.999
18.t00071	76.t00021	C4LYW6	C4LZZ6	Uncharacterized protein.	Aha1 domain protein, putative.	0.942
18.t00071	92.t00009	C4LYW6	C4LVB2	Uncharacterized protein.	Heat shock protein 90, putative.	0.999
18.t00071	92.t00037	C4LYW6	C4MBP1	Uncharacterized protein.	Heat shock protein 90, putative.	0.999
25.t00027	18.t00071	C4LUP1	C4LYW6	TPR repeat protein.	Uncharacterized protein.	0.795
25.t00027	256.t00015	C4LUP1	C4M3S9	TPR repeat protein.	90 kDa heat shock protein, putative.	0.695
25.t00027	76.t00021	C4LUP1	C4LZZ6	TPR repeat protein.	Aha1 domain protein, putative.	0.754
25.t00027	92.t00009	C4LUP1	C4LVB2	TPR repeat protein.	Heat shock protein 90, putative.	0.902
25.t00027	92.t00037	C4LUP1	C4MBP1	TPR repeat protein.	Heat shock protein 90, putative.	0.903
256.t00015	18.t00071	C4M3S9	C4LYW6	90 kDa heat shock protein, putative.	Uncharacterized protein.	0.999
256.t00015	25.t00027	C4M3S9	C4LUP1	90 kDa heat shock protein, putative.	TPR repeat protein.	0.695
256.t00015	76.t00021	C4M3S9	C4LZZ6	90 kDa heat shock protein, putative.	Aha1 domain protein, putative.	0.979
256.t00015	92.t00009	C4M3S9	C4LVB2	90 kDa heat shock protein, putative.	Heat shock protein 90, putative.	0.564
256.t00015	92.t00037	C4M3S9	C4MBP1	90 kDa heat shock protein, putative.	Heat shock protein 90, putative.	0.573
76.t00021	18.t00071	C4LZZ6	C4LYW6	Aha1 domain protein, putative.	Uncharacterized protein.	0.942
76.t00021	25.t00027	C4LZZ6	C4LUP1	Aha1 domain protein, putative.	TPR repeat protein.	0.754
76.t00021	256.t00015	C4LZZ6	C4M3S9	Aha1 domain protein, putative.	90 kDa heat shock protein, putative.	0.979
76.t00021	92.t00009	C4LZZ6	C4LVB2	Aha1 domain protein, putative.	Heat shock protein 90, putative.	0.984
76.t00021	92.t00037	C4LZZ6	C4MBP1	Aha1 domain protein, putative.	Heat shock protein 90, putative.	0.985