(18 nodes) Protein disulfide isomerase activity, and Endoplasmic reticulum chaperone complex network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EHI_133950	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (523 aa)
	3.t00064	Thioredoxin, putative. (485 aa)
	5.t00007	Thioredoxin, putative. (504 aa)
	9.t00021	Uncharacterized protein. (531 aa)
	71.t00020	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (559 aa)
	42.t00029	Thioredoxin, putative. (125 aa)
	69.t00034	Heat shock protein70, hsp70A2, putative; Belongs to the heat shock protein 70 family. (665 aa)
	177.t00017	Thioredoxin, putative. (163 aa)
	33.t00005	Calreticulin. (389 aa)
	30.t00049	Thioredoxin, putative; Belongs to the protein disulfide isomerase family. (127 aa)
	82.t00018	Thioredoxin domain-containing protein. (495 aa)
	111.t00021	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (523 aa)
	53.t00037	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (632 aa)
	45.t00013	DUF3883 domain-containing protein. (1242 aa)
	186.t00012	Thioredoxin, putative. (119 aa)
	450.t00003	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (558 aa)
	206.t00013	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (368 aa)
	418.t00001	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (557 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
111.t00021	177.t00017	C4M668	C4M242	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative.	0.534
111.t00021	186.t00012	C4M668	C4M7K9	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative.	0.716
111.t00021	206.t00013	C4M668	C4MB38	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family.	0.534
111.t00021	3.t00064	C4M668	C4LTD8	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative.	0.716
111.t00021	30.t00049	C4M668	C4M5V0	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative; Belongs to the protein disulfide isomerase family.	0.534
111.t00021	33.t00005	C4M668	C4M296	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Calreticulin.	0.774
111.t00021	418.t00001	C4M668	C4MBA9	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.610
111.t00021	42.t00029	C4M668	C4LZH6	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative.	0.534
111.t00021	5.t00007	C4M668	C4LU87	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin, putative.	0.716
111.t00021	69.t00034	C4M668	C4M1G4	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Heat shock protein70, hsp70A2, putative; Belongs to the heat shock protein 70 family.	0.586
111.t00021	82.t00018	C4M668	C4M611	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Thioredoxin domain-containing protein.	0.716
111.t00021	9.t00021	C4M668	C4LVA3	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.716
177.t00017	111.t00021	C4M242	C4M668	Thioredoxin, putative.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.534
177.t00017	186.t00012	C4M242	C4M7K9	Thioredoxin, putative.	Thioredoxin, putative.	0.458
177.t00017	3.t00064	C4M242	C4LTD8	Thioredoxin, putative.	Thioredoxin, putative.	0.458
177.t00017	33.t00005	C4M242	C4M296	Thioredoxin, putative.	Calreticulin.	0.709
177.t00017	45.t00013	C4M242	C4M781	Thioredoxin, putative.	DUF3883 domain-containing protein.	0.494
177.t00017	450.t00003	C4M242	C4MAT4	Thioredoxin, putative.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.534
177.t00017	5.t00007	C4M242	C4LU87	Thioredoxin, putative.	Thioredoxin, putative.	0.465
177.t00017	53.t00037	C4M242	C4M6K9	Thioredoxin, putative.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.534