(22 nodes) Antioxidant activity, and Protein repair network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EHI_024110	Disulphide oxidoreductase, putative. (122 aa)
	EHI_123390	Peroxiredoxin. (237 aa)
	EHI_084260	Peroxiredoxin, putative. (250 aa)
	EHI_121620	Peroxiredoxin, putative. (133 aa)
	EHI_139570	Peroxiredoxin, putative. (192 aa)
	28.t00023	Peroxiredoxin family protein. (208 aa)
	23.t00001	Thioredoxin reductase. (314 aa)
	6.t00016	Thioredoxin; Belongs to the thioredoxin family. (114 aa)
	384.t00003	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (190 aa)
	8.t00082	Thioredoxin; Belongs to the thioredoxin family. (103 aa)
	212.t00014	Thioredoxin, putative. (106 aa)
	1.t00159	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative. (184 aa)
	828.t00001	Peroxiredoxin, putative. (233 aa)
	111.t00006	Thioredoxin, putative. (144 aa)
	136.t00007	Peroxiredoxin. (234 aa)
	298.t00001	Peroxiredoxin, putative. (233 aa)
	421.t00002	Leucine rich repeat protein, BspA family. (559 aa)
	294.t00003	Peroxiredoxin. (229 aa)
	289.t00002	Thioredoxin, putative. (107 aa)
	41.t00027	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	283.t00011	Leucine rich repeat protein, BspA family. (329 aa)
	94.t00032	Peroxiredoxin, putative. (237 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00159	136.t00007	C4M1U6	C4M6Q4	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin.	0.452
1.t00159	23.t00001	C4M1U6	C4LW95	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Thioredoxin reductase.	0.535
1.t00159	28.t00023	C4M1U6	C4LV91	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin family protein.	0.459
1.t00159	294.t00003	C4M1U6	C4MAR7	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin.	0.452
1.t00159	298.t00001	C4M1U6	C4M8W7	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
1.t00159	384.t00003	C4M1U6	C4LX20	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.888
1.t00159	828.t00001	C4M1U6	C4M3Q0	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
1.t00159	94.t00032	C4M1U6	C4MBP3	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
1.t00159	EHI_024110	C4M1U6	B1N4N8	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Disulphide oxidoreductase, putative.	0.535
1.t00159	EHI_084260	C4M1U6	B1N5L9	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
1.t00159	EHI_121620	C4M1U6	B1N5Y9	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
1.t00159	EHI_123390	C4M1U6	B1N5A8	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin.	0.452
1.t00159	EHI_139570	C4M1U6	B1N623	4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme, putative.	Peroxiredoxin, putative.	0.452
111.t00006	136.t00007	C4M658	C4M6Q4	Thioredoxin, putative.	Peroxiredoxin.	0.540
111.t00006	28.t00023	C4M658	C4LV91	Thioredoxin, putative.	Peroxiredoxin family protein.	0.547
111.t00006	294.t00003	C4M658	C4MAR7	Thioredoxin, putative.	Peroxiredoxin.	0.540
111.t00006	298.t00001	C4M658	C4M8W7	Thioredoxin, putative.	Peroxiredoxin, putative.	0.540
111.t00006	828.t00001	C4M658	C4M3Q0	Thioredoxin, putative.	Peroxiredoxin, putative.	0.540
111.t00006	94.t00032	C4M658	C4MBP3	Thioredoxin, putative.	Peroxiredoxin, putative.	0.540
111.t00006	EHI_084260	C4M658	B1N5L9	Thioredoxin, putative.	Peroxiredoxin, putative.	0.540