(48 nodes) Small-subunit processome, and Regulation of transcription by RNA polymerase I network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EHI_141220	WD_REPEATS_REGION domain-containing protein. (201 aa)
	EHI_051880	WD domain containing protein. (405 aa)
	EHI_195100	Brix domain-containing protein. (297 aa)
	EHI_083380	WD_REPEATS_REGION domain-containing protein. (454 aa)
	178.t00005	U3 small nucleolar ribonucleoprotein subunit, putative. (186 aa)
	EHI_048860	U3 small nucleolar ribonucleo protein protein MPP10, putative. (215 aa)
	EHI_132140	Uncharacterized protein. (152 aa)
	EHI_027130	Uncharacterized protein. (348 aa)
	13.t00048	Uncharacterized protein. (286 aa)
	2.t00040	WD domain containing protein. (881 aa)
	1.t00079	Uncharacterized protein. (2455 aa)
	3.t00130	Ribosome biogenesis protein NEP1, putative. (227 aa)
	8.t00062	WD domain containing protein. (831 aa)
	15.t00039	WD domain containing protein. (423 aa)
	15.t00009	Uncharacterized protein. (612 aa)
	85.t00004	WD domain containing protein. (392 aa)
	309.t00003	Nucleolar protein 10, putative. (422 aa)
	48.t00006	RNA-binding protein, putative. (255 aa)
	428.t00006	Uncharacterized protein. (396 aa)
	18.t00015	U3 small nucleolar ribonucleoprotein subunit, putative. (345 aa)
	177.t00025	Uncharacterized protein. (710 aa)
	39.t00016	BP28CT domain-containing protein. (2005 aa)
	14.t00016	Uncharacterized protein. (496 aa)
	20.t00037	RNA 3'-terminal phosphate cyclase, putative. (350 aa)
	62.t00010	Fibrillarin, putative. (305 aa)
	249.t00016	WD domain containing protein. (783 aa)
	415.t00007	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (125 aa)
	76.t00028	RNA-binding protein, putative. (197 aa)
	70.t00019	U3 small nucleolar ribonucleoprotein protein IMP4, putative. (273 aa)
	19.t00035	WD domain containing protein. (486 aa)
	1.t00047	WD repeat protein. (492 aa)
	307.t00003	Uncharacterized protein. (558 aa)
	7.t00057	Uncharacterized protein. (668 aa)
	60.t00003	WD domain containing protein. (775 aa)
	387.t00002	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (978 aa)
	90.t00020	WD domain containing protein. (884 aa)
	59.t00011	U3 small nucleolar RNA-associated protein 11, putative. (207 aa)
	59.t00019	Nucleolar protein Nop56, putative. (453 aa)
	108.t00021	Nuclear complex protein 4, putative. (333 aa)
	202.t00010	Uncharacterized protein. (191 aa)
	484.t00001	WD domain containing protein. (696 aa)
	254.t00004	RNA 3'-terminal phosphate cyclase, putative. (357 aa)
	59.t00026	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (130 aa)
	299.t00008	Ribosome biogenesis protein BMS1, putative. (975 aa)
	31.t00040	WD repeat protein. (456 aa)
	420.t00001	rRNA biogenesis protein RRP5, putative. (811 aa)
	528.t00002	SnoRNA binding protein, putative. (503 aa)
	22.t00059	WD_REPEATS_REGION domain-containing protein. (458 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00047	1.t00079	C4M1V9	C4LT45	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	108.t00021	C4M1V9	C4M5T1	WD repeat protein.	Nuclear complex protein 4, putative.	0.999
1.t00047	13.t00048	C4M1V9	C4LSB9	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	14.t00016	C4M1V9	C4LX68	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	15.t00009	C4M1V9	C4LUX0	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	15.t00039	C4M1V9	C4LUV0	WD repeat protein.	WD domain containing protein.	0.993
1.t00047	177.t00025	C4M1V9	C4LWN4	WD repeat protein.	Uncharacterized protein.	0.995
1.t00047	178.t00005	C4M1V9	B1N507	WD repeat protein.	U3 small nucleolar ribonucleoprotein subunit, putative.	0.999
1.t00047	18.t00015	C4M1V9	C4LW64	WD repeat protein.	U3 small nucleolar ribonucleoprotein subunit, putative.	0.992
1.t00047	19.t00035	C4M1V9	C4M1D2	WD repeat protein.	WD domain containing protein.	0.999
1.t00047	2.t00040	C4M1V9	C4LSH9	WD repeat protein.	WD domain containing protein.	0.999
1.t00047	20.t00037	C4M1V9	C4LY11	WD repeat protein.	RNA 3'-terminal phosphate cyclase, putative.	0.981
1.t00047	202.t00010	C4M1V9	C4M6Z5	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	22.t00059	C4M1V9	C4MBB9	WD repeat protein.	WD_REPEATS_REGION domain-containing protein.	0.982
1.t00047	249.t00016	C4M1V9	C4LYT7	WD repeat protein.	WD domain containing protein.	0.989
1.t00047	254.t00004	C4M1V9	C4M8E8	WD repeat protein.	RNA 3'-terminal phosphate cyclase, putative.	0.981
1.t00047	299.t00008	C4M1V9	C4M9R3	WD repeat protein.	Ribosome biogenesis protein BMS1, putative.	0.999
1.t00047	3.t00130	C4M1V9	C4LT83	WD repeat protein.	Ribosome biogenesis protein NEP1, putative.	0.999
1.t00047	307.t00003	C4M1V9	C4M2K2	WD repeat protein.	Uncharacterized protein.	0.999
1.t00047	309.t00003	C4M1V9	C4LW22	WD repeat protein.	Nucleolar protein 10, putative.	0.998