(11 nodes) Preribosome, large subunit precursor, and Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	15.t00016	rRNA processing protein, putative. (208 aa)
	215.t00011	Nucleolar phosphoprotein Nopp34, putative. (153 aa)
	221.t00012	Ribosome biogenesis protein, putative. (311 aa)
	34.t00039	Protein MAK16 homolog; Belongs to the MAK16 family. (264 aa)
	39.t00015	Proliferating-cell nucleolar antigen p120, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (495 aa)
	18.t00050	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (406 aa)
	262.t00008	Ribosome biogenesis protein, putative. (291 aa)
	368.t00004	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (545 aa)
	74.t00033	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (605 aa)
	29.t00039	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (829 aa)
	302.t00001	Uncharacterized protein. (298 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
15.t00016	18.t00050	B1N2M7	C4LYY7	rRNA processing protein, putative.	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	0.998
15.t00016	215.t00011	B1N2M7	C4LU58	rRNA processing protein, putative.	Nucleolar phosphoprotein Nopp34, putative.	0.998
15.t00016	221.t00012	B1N2M7	C4LVY6	rRNA processing protein, putative.	Ribosome biogenesis protein, putative.	0.998
15.t00016	262.t00008	B1N2M7	C4LZN4	rRNA processing protein, putative.	Ribosome biogenesis protein, putative.	0.999
15.t00016	29.t00039	B1N2M7	C4M6R5	rRNA processing protein, putative.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.997
15.t00016	302.t00001	B1N2M7	C4M977	rRNA processing protein, putative.	Uncharacterized protein.	0.998
15.t00016	34.t00039	B1N2M7	C4LWR5	rRNA processing protein, putative.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.996
15.t00016	368.t00004	B1N2M7	C4M0Q1	rRNA processing protein, putative.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.995
15.t00016	39.t00015	B1N2M7	C4LWT4	rRNA processing protein, putative.	Proliferating-cell nucleolar antigen p120, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.996
15.t00016	74.t00033	B1N2M7	C4M3V4	rRNA processing protein, putative.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.999
18.t00050	15.t00016	C4LYY7	B1N2M7	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	rRNA processing protein, putative.	0.998
18.t00050	215.t00011	C4LYY7	C4LU58	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Nucleolar phosphoprotein Nopp34, putative.	0.998
18.t00050	221.t00012	C4LYY7	C4LVY6	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Ribosome biogenesis protein, putative.	0.996
18.t00050	262.t00008	C4LYY7	C4LZN4	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Ribosome biogenesis protein, putative.	0.996
18.t00050	29.t00039	C4LYY7	C4M6R5	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.994
18.t00050	302.t00001	C4LYY7	C4M977	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Uncharacterized protein.	0.996
18.t00050	34.t00039	C4LYY7	C4LWR5	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.996
18.t00050	368.t00004	C4LYY7	C4M0Q1	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.998
18.t00050	39.t00015	C4LYY7	C4LWT4	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Proliferating-cell nucleolar antigen p120, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.997
18.t00050	74.t00033	C4LYY7	C4M3V4	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.999