STRINGSTRING
EHI_141410 EHI_141410 EHI_129630 EHI_129630 2.t00064 2.t00064 8.t00042 8.t00042 300.t00001 300.t00001 129.t00030 129.t00030 44.t00003 44.t00003 53.t00034 53.t00034 180.t00010 180.t00010 4.t00129 4.t00129 73.t00009 73.t00009 1.t00017 1.t00017 318.t00007 318.t00007 135.t00016 135.t00016 173.t00021 173.t00021 FEN1 FEN1 51.t00007 51.t00007 213.t00004 213.t00004 277.t00004 277.t00004 59.t00030 59.t00030 180.t00016 180.t00016 161.t00010 161.t00010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EHI_141410Uncharacterized protein. (395 aa)
EHI_129630DNA primase small subunit, putative. (189 aa)
2.t00064DNA polymerase. (1132 aa)
8.t00042DNA polymerase. (1385 aa)
300.t00001DNA primase; Belongs to the eukaryotic-type primase small subunit family. (380 aa)
129.t00030DNA primase large subunit, putative. (457 aa)
44.t00003Replication factor C subunit 4, putative. (329 aa)
53.t00034DNA polymerase. (1077 aa)
180.t00010Uncharacterized protein. (440 aa)
4.t00129DNA primase; Belongs to the eukaryotic-type primase small subunit family. (372 aa)
73.t00009Activator 1 subunit, putative. (331 aa)
1.t00017DNA ligase. (685 aa)
318.t00007Activator 1 subunit, putative. (345 aa)
135.t00016Uncharacterized protein. (244 aa)
173.t00021Replication factor C familiy protein. (325 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (376 aa)
51.t00007DNA primase large subunit, putative. (523 aa)
213.t00004DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (319 aa)
277.t00004Activator 1 140 kDa subunit, putative. (718 aa)
59.t00030Deoxycytidyl transferase, putative. (708 aa)
180.t00016Activator 1 40 kDa subunit, putative. (315 aa)
161.t00010Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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