STRINGSTRING
EHI_024240 EHI_024240 EHI_030180 EHI_030180 EHI_177870 EHI_177870 EHI_002010 EHI_002010 EHI_082380 EHI_082380 EHI_160670 EHI_160670 EHI_157770 EHI_157770 EHI_072240 EHI_072240 6.t00099 6.t00099 31.t00001 31.t00001 61.t00038 61.t00038 81.t00034 81.t00034 15.t00060 15.t00060 348.t00008 348.t00008 12.t00050 12.t00050 224.t00017 224.t00017 12.t00038 12.t00038 11.t00060 11.t00060 32.t00018 32.t00018 34.t00053 34.t00053 34.t00046 34.t00046 345.t00008 345.t00008 223.t00001 223.t00001 337.t00001 337.t00001 3.t00032 3.t00032 349.t00010 349.t00010 91.t00031 91.t00031 20.t00015 20.t00015 53.t00013 53.t00013 151.t00003 151.t00003 105.t00016 105.t00016 75.t00020 75.t00020 19.t00043 19.t00043 246.t00005 246.t00005 54.t00012 54.t00012 216.t00001 216.t00001 34.t00011 34.t00011 124.t00001 124.t00001 242.t00015 242.t00015 133.t00007 133.t00007 22.t00022 22.t00022 4.t00078 4.t00078 74.t00023 74.t00023 100.t00008 100.t00008 11.t00020 11.t00020 11.t00007 11.t00007 147.t00009 147.t00009 146.t00012 146.t00012 10.t00015 10.t00015 26.t00064 26.t00064 346.t00002 346.t00002 202.t00008 202.t00008 226.t00013 226.t00013 466.t00004 466.t00004 196.t00020 196.t00020 73.t00013 73.t00013 90.t00031 90.t00031 260.t00004 260.t00004 188.t00008 188.t00008 382.t00004 382.t00004 156.t00004 156.t00004 161.t00016 161.t00016 HXK1 HXK1 HXK2 HXK2 PPi-PFK PPi-PFK 349.t00005 349.t00005 G6PI G6PI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EHI_024240Aldehyde-alcohol dehydrogenase 2, putative. (829 aa)
EHI_030180Alcohol dehydrogenase 3, putative. (98 aa)
EHI_177870Transketolase, putative. (676 aa)
EHI_002010Mannose-6-phosphate isomerase, putative. (241 aa)
EHI_082380Transketolase, chloroplast, putative. (185 aa)
EHI_160670Alcohol dehydrogenase 3, putative. (222 aa)
EHI_157770Transketolase, putative. (457 aa)
EHI_072240Glucose-6-phosphate isomerase, putative. (164 aa)
6.t00099Serine palmitoyltransferase, putative. (883 aa)
31.t00001Metallo-beta-lactamase family protein. (214 aa)
61.t00038Metallo-beta-lactamase family protein. (217 aa)
81.t00034NADP-dependent alcohol dehydrogenase. (366 aa)
15.t00060HAD hydrolase, family IA, variant 3. (229 aa)
348.t00008Phosphoglycerate mutase family protein. (201 aa)
12.t000503-oxoacyl-(Acyl-carrier protein) reductase, putative. (265 aa)
224.t00017Glyceraldehyde-3-phosphate dehydrogenase. (334 aa)
12.t00038Phosphofructokinase, putative. (439 aa)
11.t00060Oxidoreductase, putative. (316 aa)
32.t00018Serine palmitoyltransferase, putative. (882 aa)
34.t00053Alcohol dehydrogenase 3, putative. (384 aa)
34.t00046ADP-ribosylglycohydrolase, putative. (432 aa)
345.t00008Pyruvate kinase; Belongs to the pyruvate kinase family. (321 aa)
223.t00001Fructose-1,6-bisphosphate aldolase, putative. (330 aa)
337.t00001Enolase, putative. (436 aa)
3.t00032Phosphoglycerate mutase domain family protein. (693 aa)
349.t00010Galactokinase, putative. (389 aa)
91.t00031Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK [...] (546 aa)
20.t00015Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (315 aa)
53.t00013Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
151.t00003Uncharacterized protein. (118 aa)
105.t00016NADP-dependent alcohol dehydrogenase, putative. (367 aa)
75.t00020Phosphoglycerate kinase. (415 aa)
19.t00043Beta-galactosidase, putative. (567 aa)
246.t00005Phosphoglucomutase/phosphomannomutase family protein. (454 aa)
54.t00012Uncharacterized protein. (267 aa)
216.t00001Uncharacterized protein. (298 aa)
34.t00011Glycerol kinase, putative; Belongs to the FGGY kinase family. (485 aa)
124.t00001Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (870 aa)
242.t00015Uncharacterized protein. (311 aa)
133.t00007Fructokinase, putative. (294 aa)
22.t00022Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (870 aa)
4.t00078RNA-binding protein, putative. (337 aa)
74.t00023Phosphofructokinase, putative. (439 aa)
100.t00008Haloacid dehalogenase-like hydrolase domain-containing protein. (227 aa)
11.t00020Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (529 aa)
11.t00007NADP-dependent alcohol dehydrogenase, putative. (343 aa)
147.t00009Deoxyribose-phosphate aldolase, putative. (218 aa)
146.t00012Phosphoglycerate mutase family protein. (205 aa)
10.t00015(2r)-phospho-3-sulfolactate synthase, putative. (259 aa)
26.t00064Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (243 aa)
346.t00002Alcohol dehydrogenase, putative. (382 aa)
202.t00008Triosephosphate isomerase. (261 aa)
226.t00013UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (341 aa)
466.t00004Aldose reductase, putative. (305 aa)
196.t00020Transketolase, putative. (661 aa)
73.t00013Aldose reductase, putative. (305 aa)
90.t00031Phosphomannose isomerase, putative. (372 aa)
260.t00004Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (272 aa)
188.t00008Short chain dehydrogenase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
382.t00004Transketolase, putative. (502 aa)
156.t00004Ribose 5-phosphate isomerase, putative. (146 aa)
161.t00016Short chain dehydrogenase family protein. (305 aa)
HXK1Phosphotransferase. (445 aa)
HXK2Phosphotransferase. (445 aa)
PPi-PFKATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (436 aa)
349.t00005Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (341 aa)
G6PIGlucose-6-phosphate isomerase; Belongs to the GPI family. (546 aa)
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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