STRINGSTRING
7.t00018 7.t00018 EHI_153810 EHI_153810 EHI_098370 EHI_098370 EHI_021380 EHI_021380 LSM8 LSM8 EHI_027560 EHI_027560 EHI_150160 EHI_150160 EHI_040480 EHI_040480 EHI_076840 EHI_076840 EHI_077220 EHI_077220 EHI_128220 EHI_128220 EHI_129760 EHI_129760 31.t00025 31.t00025 EHI_080750 EHI_080750 EHI_085470 EHI_085470 13.t00023 13.t00023 13.t00017 13.t00017 2.t00032 2.t00032 22.t00040 22.t00040 2.t00106 2.t00106 2.t00004 2.t00004 1.t00120 1.t00120 1.t00062 1.t00062 1.t00058 1.t00058 64.t00037 64.t00037 3.t00076 3.t00076 3.t00075 3.t00075 3.t00072 3.t00072 3.t00063 3.t00063 3.t00061 3.t00061 72.t00013 72.t00013 31.t00014 31.t00014 10.t00027 10.t00027 8.t00061 8.t00061 61.t00012 61.t00012 61.t00040 61.t00040 58.t00033 58.t00033 LSM4 LSM4 21.t00036 21.t00036 96.t00002 96.t00002 15.t00067 15.t00067 15.t00053 15.t00053 15.t00020 15.t00020 50.t00031 50.t00031 204.t00007 204.t00007 343.t00005 343.t00005 39.t00039 39.t00039 12.t00018 12.t00018 465.t00006 465.t00006 117.t00032 117.t00032 117.t00038 117.t00038 48.t00017 48.t00017 6.t00018 6.t00018 6.t00035 6.t00035 194.t00015 194.t00015 34.t00052 34.t00052 230.t00015 230.t00015 87.t00025 87.t00025 155.t00010 155.t00010 14.t00046 14.t00046 14.t00054 14.t00054 77.t00025 77.t00025 77.t00020 77.t00020 77.t00019 77.t00019 9.t00070 9.t00070 216.t00008 216.t00008 37.t00038 37.t00038 169.t00007 169.t00007 17.t00036 17.t00036 17.t00041 17.t00041 17.t00048 17.t00048 20.t00036 20.t00036 402.t00001 402.t00001 55.t00006 55.t00006 55.t00023 55.t00023 78.t00002 78.t00002 3.t00048 3.t00048 3.t00022 3.t00022 18.t00059 18.t00059 47.t00012 47.t00012 415.t00007 415.t00007 210.t00008 210.t00008 106.t00006 106.t00006 91.t00006 91.t00006 91.t00007 91.t00007 91.t00009 91.t00009 7.t00046 7.t00046 201.t00018 201.t00018 201.t00013 201.t00013 203.t00019 203.t00019 103.t00029 103.t00029 178.t00012 178.t00012 153.t00011 153.t00011 75.t00036 75.t00036 75.t00014 75.t00014 19.t00055 19.t00055 19.t00042 19.t00042 19.t00038 19.t00038 77.t00007 77.t00007 69.t00026 69.t00026 69.t00024 69.t00024 29.t00024 29.t00024 212.t00009 212.t00009 1.t00023 1.t00023 1.t00039 1.t00039 22.t00011 22.t00011 177.t00022 177.t00022 33.t00006 33.t00006 33.t00030 33.t00030 198.t00006 198.t00006 144.t00004 144.t00004 144.t00006 144.t00006 40.t00021 40.t00021 448.t00002 448.t00002 208.t00013 208.t00013 128.t00009 128.t00009 256.t00007 256.t00007 74.t00043 74.t00043 109.t00016 109.t00016 206.t00006 206.t00006 72.t00035 72.t00035 150.t00019 150.t00019 108.t00016 108.t00016 108.t00012 108.t00012 108.t00010 108.t00010 100.t00009 100.t00009 100.t00020 100.t00020 243.t00007 243.t00007 313.t00006 313.t00006 134.t00021 134.t00021 134.t00020 134.t00020 110.t00023 110.t00023 230.t00023 230.t00023 59.t00037 59.t00037 54.t00054 54.t00054 414.t00003 414.t00003 26.t00046 26.t00046 135.t00015 135.t00015 51.t00022 51.t00022 89.t00010 89.t00010 89.t00016 89.t00016 51.t00011 51.t00011 391.t00002 391.t00002 336.t00001 336.t00001 193.t00008 193.t00008 193.t00006 193.t00006 39.t00057 39.t00057 309.t00007 309.t00007 45.t00005 45.t00005 45.t00008 45.t00008 372.t00006 372.t00006 30.t00018 30.t00018 8.t00008 8.t00008 49.t00035 49.t00035 163.t00015 163.t00015 407.t00006 407.t00006 170.t00019 170.t00019 5.t00088 5.t00088 286.t00007 286.t00007 254.t00012 254.t00012 59.t00026 59.t00026 297.t00006 297.t00006 223.t00003 223.t00003 293.t00010 293.t00010 180.t00014 180.t00014 333.t00005 333.t00005 333.t00008 333.t00008 392.t00003 392.t00003 54.t00046 54.t00046 4.t00062 4.t00062 319.t00007 319.t00007 344.t00001 344.t00001 165.t00012 165.t00012 283.t00009 283.t00009 136.t00018 136.t00018 404.t00007 404.t00007 3.t00001 3.t00001 902.t00001 902.t00001 13.t00007 13.t00007 253.t00012 253.t00012 447.t00009 447.t00009 5.t00013 5.t00013 22.t00005 22.t00005 57.t00015 57.t00015 146.t00005 146.t00005 16.t00038 16.t00038 Caf1 Caf1 CFIm25 CFIm25 HCP HCP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
7.t00018Splicing factor 3A subunit 3, putative. (460 aa)
EHI_153810RNA recognition motif domain containing protein. (372 aa)
EHI_098370Cleavage stimulation factor, putative. (550 aa)
EHI_021380U5 small nuclear ribonucleoprotein subunit, putative. (954 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa)
EHI_027560Pre-mRNA-splicing factor PRP46, putative. (276 aa)
EHI_150160ATP-dependent RNA helicase DDX39, putative. (241 aa)
EHI_040480mRNA cap guanine-N7 methyltransferase, putative. (208 aa)
EHI_076840Uncharacterized protein. (83 aa)
EHI_077220Pre-mRNA cleavage factor I 25 kDa subunit, putative. (129 aa)
EHI_1282205'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (869 aa)
EHI_129760SON DNA binding protein, putative. (190 aa)
31.t00025Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (107 aa)
EHI_080750Uncharacterized protein. (213 aa)
EHI_085470Splicing factor3B subunit 1, putative. (460 aa)
13.t00023Pre-mRNA-splicing factor PRP46, putative. (311 aa)
13.t00017U1 small nuclear ribonucleoprotein subunit, putative. (509 aa)
2.t00032U6 snRNA-associated Sm-like protein LSm3, putative. (78 aa)
22.t00040Helicase, putative. (419 aa)
2.t00106Pseudouridine synthase, putative. (366 aa)
2.t00004Ubiquitin carboxyl-terminal hydrolase domain containing protein. (444 aa)
1.t00120Transcription initiation protein SPT4, putative. (128 aa)
1.t00062Helicase, putative. (811 aa)
1.t00058Regulator of nonsense transcripts, putative. (966 aa)
64.t00037DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa)
3.t00076Uncharacterized protein. (428 aa)
3.t00075SLBP_RNA_bind domain-containing protein. (196 aa)
3.t00072U5 snRNP-specific 200kd protein, putative. (1799 aa)
3.t00063DIM1 family protein, putative. (142 aa)
3.t00061RNA recognition motif domain containing protein. (311 aa)
72.t00013Uncharacterized protein. (336 aa)
31.t00014Splicing factor 3B subunit 4, putative. (199 aa)
10.t00027U1snRNP-specific protein, putative. (232 aa)
8.t00061Cell cycle control protein cwf5, putative. (184 aa)
61.t00012Protein kinase, putative. (765 aa)
61.t00040U6 snRNA-associated Sm-like protein LSm2, putative. (62 aa)
58.t00033Regulator of nonsense transcripts, putative. (965 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (81 aa)
21.t00036SAC3/GANP family protein. (333 aa)
96.t00002Regulator of nonsense transcripts, putative. (915 aa)
15.t00067Histone RNA hairpin-binding protein, putative. (216 aa)
15.t00053Uncharacterized protein. (1999 aa)
15.t00020tRNA pseudouridine synthase, putative. (401 aa)
50.t00031Uncharacterized protein. (1231 aa)
204.t00007RNA recognition motif domain containing protein. (135 aa)
343.t00005WD domain containing protein. (291 aa)
39.t00039DnaJ domain containing protein. (206 aa)
12.t00018Cell cycle control protein cwf12, putative. (176 aa)
465.t00006Cell cycle control protein cwf2, putative. (355 aa)
117.t00032WD domain containing protein. (400 aa)
117.t000383' exoribonuclease family protein. (227 aa)
48.t00017Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (89 aa)
6.t00018Helicase, putative. (675 aa)
6.t00035DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family. (535 aa)
194.t00015Splicing factor3B subunit 2, putative. (207 aa)
34.t00052Polyadenylate-binding protein, putative. (524 aa)
230.t00015Splicing factor, putative. (231 aa)
87.t00025SAC3/GANP family protein. (485 aa)
155.t00010Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (226 aa)
14.t00046Splicing factor, putative. (159 aa)
14.t00054Pre-mRNA-splicing factor, putative. (176 aa)
77.t00025MutT/nudix family protein. (286 aa)
77.t00020U2 snRNP auxiliary factor large subunit, putative. (712 aa)
77.t00019Microfibril-associated protein, putative. (242 aa)
9.t00070Uncharacterized protein. (699 aa)
216.t00008DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family. (722 aa)
37.t00038Retinoblatoma-binding protein 6, putative. (394 aa)
169.t00007Protein kinase, putative; Belongs to the protein kinase superfamily. (370 aa)
17.t00036Protein kinase, putative. (371 aa)
17.t00041Regulator of nonsense transcripts, putative. (937 aa)
17.t00048mRNA_cap_enzyme domain-containing protein. (568 aa)
20.t00036RNA recognition motif domain containing protein. (281 aa)
402.t00001CDC73_C domain-containing protein. (218 aa)
55.t00006Uncharacterized protein. (109 aa)
55.t00023ATP/GTP-binding protein, putative. (429 aa)
78.t00002Uncharacterized protein. (338 aa)
3.t00048Cell cycle control protein, putative. (552 aa)
3.t00022Pre-mRNA splicing factor, putative. (870 aa)
18.t00059Splicing factor 3a subunit 2, putative. (218 aa)
47.t00012RNA recognition motif domain containing protein. (178 aa)
415.t00007Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (125 aa)
210.t00008Protein kinase, putative. (386 aa)
106.t00006PRP38 family protein. (190 aa)
91.t00006Myb-like DNA-binding domain containing protein. (238 aa)
91.t00007Uncharacterized protein. (174 aa)
91.t00009Exosome complex exonuclease, putative. (265 aa)
7.t00046CAF1 family ribonuclease, putative. (303 aa)
201.t00018Exosome component 10, putative. (517 aa)
201.t00013DEAD/DEAH box helicase, putative; Belongs to the DEAD box helicase family. (585 aa)
203.t00019Uncharacterized protein. (233 aa)
103.t00029Uncharacterized protein. (861 aa)
178.t00012Uncharacterized protein. (536 aa)
153.t00011Uncharacterized protein. (133 aa)
75.t000363' exoribonuclease family protein. (265 aa)
75.t00014Small nuclear ribonucleoprotein F, putative. (83 aa)
19.t00055RNA recognition motif domain containing protein. (112 aa)
19.t00042F-box/WD domain containing protein. (631 aa)
19.t00038Cleavage stimulation factor, putative. (550 aa)
77.t00007WD domain containing protein. (460 aa)
69.t00026Scavenger mRNA decapping enzyme, putative. (281 aa)
69.t00024U2 snRNP auxiliary factor, putative. (251 aa)
29.t00024Regulator of nonsense transcripts, putative. (909 aa)
212.t00009RNA lariat debranching enzyme, putative. (354 aa)
1.t00023Uncharacterized protein. (201 aa)
1.t00039Uncharacterized protein. (375 aa)
22.t00011EF-hand calcium-binding domain containing protein. (261 aa)
177.t00022Uncharacterized protein. (123 aa)
33.t00006Cleavage and polyadenylation specificity factor 73 kDa subunit, putative. (755 aa)
33.t00030SAC3/GANP family protein. (670 aa)
198.t00006RNA-binding protein, putative. (255 aa)
144.t00004WD domain containing protein. (426 aa)
144.t000063' exoribonuclease family protein. (238 aa)
40.t00021Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (255 aa)
448.t00002Cleavage and polyadenylation specificity factor subunit, putative. (1150 aa)
208.t00013Crooked neck protein, putative. (473 aa)
128.t00009mRNA capping enzyme, putative. (595 aa)
256.t00007Exosome complex exonuclease RRP4, putative. (263 aa)
74.t00043Small nuclear ribonucleoprotein Sm D3. (111 aa)
109.t00016Uncharacterized protein. (1598 aa)
206.t00006DEAD/DEAH box helicase, putative. (757 aa)
72.t00035Uncharacterized protein. (241 aa)
150.t00019tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (515 aa)
108.t00016Splicing factor 3b subunit 3, putative. (1108 aa)
108.t00012Splicing factor, arginine/serine-rich, putative. (199 aa)
108.t00010Uncharacterized protein. (430 aa)
100.t00009Nuclear cap-binding protein subunit 2. (184 aa)
100.t00020U2 auxiliary factor, putative. (227 aa)
243.t00007Small nuclear ribonucleoprotein G. (81 aa)
313.t00006mRNA capping methyltransferase, putative. (290 aa)
134.t00021RNA-binding protein, putative. (309 aa)
134.t00020Regulator of nonsense transcripts, putative. (931 aa)
110.t00023FHA domain protein, putative. (180 aa)
230.t00023mRNA decapping protein, putative. (232 aa)
59.t00037Helicase, putative. (845 aa)
54.t00054Regulator of nonsense transcripts, putative. (979 aa)
414.t00003DEAD/DEAH box helicase, putative. (1062 aa)
26.t00046Uncharacterized protein. (140 aa)
135.t00015Uncharacterized protein. (109 aa)
51.t00022Uncharacterized protein. (670 aa)
89.t00010Small nuclear ribonucleoprotein F, putative. (205 aa)
89.t00016Splicing factor Prp8, putative. (2270 aa)
51.t00011Pre-mRNA splicing factor, putative. (453 aa)
391.t00002Uncharacterized protein. (1372 aa)
336.t00001Helicase, putative. (953 aa)
193.t00008Cleavage and polyadenylation specificity factor subunit 2. (514 aa)
193.t00006Polyadenylate-binding protein, putative. (514 aa)
39.t00057RRM domain-containing protein. (84 aa)
309.t00007Fip1 domain-containing protein. (219 aa)
45.t00005SKIP/SNW domain protein. (308 aa)
45.t00008Uncharacterized protein. (634 aa)
372.t00006Regulator of nonsense transcripts, putative. (896 aa)
30.t00018AAA_11 domain-containing protein. (707 aa)
8.t00008U5 small nuclear ribonucleoprotein subunit, putative. (954 aa)
49.t00035Uncharacterized protein. (264 aa)
163.t00015CCR4/NOT transcription complex subunit 3, putative. (482 aa)
407.t00006Uncharacterized protein. (484 aa)
170.t00019Small nuclear ribonucleoprotein Sm D2. (101 aa)
5.t00088Uncharacterized protein. (843 aa)
286.t00007Uncharacterized protein. (993 aa)
254.t00012Centromere/microtubule binding protein cbf5, putative. (484 aa)
59.t00026Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (130 aa)
297.t000065'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (779 aa)
223.t00003Scavenger mRNA decapping enzyme, putative. (287 aa)
293.t000105'-3' exonuclease domain containing protein. (628 aa)
180.t000143' exoribonuclease family protein. (223 aa)
333.t00005Uncharacterized protein. (200 aa)
333.t00008Uncharacterized protein. (220 aa)
392.t00003LSM domain containing protein. (91 aa)
54.t00046Uncharacterized protein. (256 aa)
4.t00062Zinc finger protein, putative. (178 aa)
319.t00007Uncharacterized protein. (429 aa)
344.t00001DNA-directed RNA polymerase II subunit, putative. (137 aa)
165.t00012Splicing factor subunit; Belongs to the SF3B5 family. (100 aa)
283.t00009DEAD/DEAH box helicase, putative. (419 aa)
136.t00018Splicing factor 3B subunit 3, putative. (1145 aa)
404.t00007Ubiquitin-like protein 5, putative. (79 aa)
3.t00001Pelota protein, putative. (403 aa)
902.t00001Splicing factor 3B subunit 1, putative. (914 aa)
13.t00007U2 snRNP auxiliary factor small subunit, putative. (279 aa)
253.t00012Protein kinase, putative. (779 aa)
447.t00009Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (225 aa)
5.t000135'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (937 aa)
22.t000055'-3' exonuclease domain containing protein. (666 aa)
57.t00015RNA recognition motif domain containing protein. (284 aa)
146.t00005SON DNA-binding protein, putative. (220 aa)
16.t00038Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. May acquire specificity through interaction with a cleavage and polyadenylation factor. (522 aa)
Caf1CAF1 family ribonuclease, putative. (311 aa)
CFIm25Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (236 aa)
HCPHydroxylamine reductase, putative. (539 aa)
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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