22 items (Entamoeba histolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	meth	DNA (Cytosine-5)-methyltransferase, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (322 aa)
	81.t00009	Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
	11.t00034	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative. (381 aa)
	107.t00019	Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (293 aa)
	65.t00026	Autophagy protein apg7, putative. (581 aa)
	17.t00065	Ras GTPase activating protein, putative. (787 aa)
	66.t00016	Protein kinase domain containing protein. (518 aa)
	56.t00005	AMP deaminase, putative. (1327 aa)
	143.t00003	Protein kinase domain containing protein. (561 aa)
	97.t00017	Protein kinase domain containing protein. (600 aa)
	30.t00046	ENTH domain protein, putative. (699 aa)
	147.t00016	Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (382 aa)
	288.t00005	Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (335 aa)
	370.t00005	I/LWEQ domain protein. (995 aa)
	370.t00002	Protein kinase domain containing protein. (386 aa)
	73.t00003	S phingosine-1-phosphate lyase 1, putative. (514 aa)
	110.t00025	AMP deaminase, putative. (1261 aa)
	EHI_175290	Sphingosine-1-phosphate lyase, putative. (110 aa)
	EHI_162340	Serine/threonine kinase 3, putative. (607 aa)
	2.t00090	F-box/WD domain containing protein. (720 aa)
	6.t00087	Cell division protein kinase, putative. (292 aa)
	1.t00135	Protein kinase, putative; Belongs to the protein kinase superfamily. (370 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00135	107.t00019	C4LSZ2	C4M2Y4	Protein kinase, putative; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.456
1.t00135	2.t00090	C4LSZ2	C4LSM0	Protein kinase, putative; Belongs to the protein kinase superfamily.	F-box/WD domain containing protein.	0.401
1.t00135	6.t00087	C4LSZ2	C4LST0	Protein kinase, putative; Belongs to the protein kinase superfamily.	Cell division protein kinase, putative.	0.421
107.t00019	1.t00135	C4M2Y4	C4LSZ2	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.456
107.t00019	147.t00016	C4M2Y4	C4M5D4	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.422
107.t00019	370.t00002	C4M2Y4	C4M9B3	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein.	0.437
11.t00034	30.t00046	C4M4F5	C4M5V3	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative.	ENTH domain protein, putative.	0.422
11.t00034	370.t00005	C4M4F5	C4M9B6	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative.	I/LWEQ domain protein.	0.422
143.t00003	65.t00026	C4M7D1	C4M0D6	Protein kinase domain containing protein.	Autophagy protein apg7, putative.	0.710
143.t00003	81.t00009	C4M7D1	C4LUK1	Protein kinase domain containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.817
147.t00016	107.t00019	C4M5D4	C4M2Y4	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.422
2.t00090	1.t00135	C4LSM0	C4LSZ2	F-box/WD domain containing protein.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.401
2.t00090	65.t00026	C4LSM0	C4M0D6	F-box/WD domain containing protein.	Autophagy protein apg7, putative.	0.496
30.t00046	11.t00034	C4M5V3	C4M4F5	ENTH domain protein, putative.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative.	0.422
370.t00002	107.t00019	C4M9B3	C4M2Y4	Protein kinase domain containing protein.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.437
370.t00002	6.t00087	C4M9B3	C4LST0	Protein kinase domain containing protein.	Cell division protein kinase, putative.	0.412
370.t00005	11.t00034	C4M9B6	C4M4F5	I/LWEQ domain protein.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, putative.	0.422
6.t00087	1.t00135	C4LST0	C4LSZ2	Cell division protein kinase, putative.	Protein kinase, putative; Belongs to the protein kinase superfamily.	0.421
6.t00087	370.t00002	C4LST0	C4M9B3	Cell division protein kinase, putative.	Protein kinase domain containing protein.	0.412
65.t00026	143.t00003	C4M0D6	C4M7D1	Autophagy protein apg7, putative.	Protein kinase domain containing protein.	0.710