(22 nodes) 90S preribosome network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	299.t00008	Ribosome biogenesis protein BMS1, putative. (975 aa)
	EHI_195100	Brix domain-containing protein. (297 aa)
	EHI_094780	Pescadillo homolog, putative. (163 aa)
	178.t00005	U3 small nucleolar ribonucleoprotein subunit, putative. (186 aa)
	EHI_048860	U3 small nucleolar ribonucleo protein protein MPP10, putative. (215 aa)
	2.t00040	WD domain containing protein. (881 aa)
	8.t00062	WD domain containing protein. (831 aa)
	15.t00009	Uncharacterized protein. (612 aa)
	85.t00004	WD domain containing protein. (392 aa)
	18.t00015	U3 small nucleolar ribonucleoprotein subunit, putative. (345 aa)
	39.t00016	BP28CT domain-containing protein. (2005 aa)
	14.t00016	Uncharacterized protein. (496 aa)
	249.t00016	WD domain containing protein. (783 aa)
	70.t00019	U3 small nucleolar ribonucleoprotein protein IMP4, putative. (273 aa)
	368.t00004	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (545 aa)
	60.t00003	WD domain containing protein. (775 aa)
	74.t00033	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (605 aa)
	90.t00020	WD domain containing protein. (884 aa)
	108.t00021	Nuclear complex protein 4, putative. (333 aa)
	71.t00024	Uncharacterized protein. (554 aa)
	484.t00001	WD domain containing protein. (696 aa)
	9.t00076	Nucleolar complex protein 2 homolog, putative. (508 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
108.t00021	14.t00016	C4M5T1	C4LX68	Nuclear complex protein 4, putative.	Uncharacterized protein.	0.999
108.t00021	15.t00009	C4M5T1	C4LUX0	Nuclear complex protein 4, putative.	Uncharacterized protein.	0.999
108.t00021	178.t00005	C4M5T1	B1N507	Nuclear complex protein 4, putative.	U3 small nucleolar ribonucleoprotein subunit, putative.	0.997
108.t00021	18.t00015	C4M5T1	C4LW64	Nuclear complex protein 4, putative.	U3 small nucleolar ribonucleoprotein subunit, putative.	0.987
108.t00021	2.t00040	C4M5T1	C4LSH9	Nuclear complex protein 4, putative.	WD domain containing protein.	0.999
108.t00021	249.t00016	C4M5T1	C4LYT7	Nuclear complex protein 4, putative.	WD domain containing protein.	0.984
108.t00021	299.t00008	C4M5T1	C4M9R3	Nuclear complex protein 4, putative.	Ribosome biogenesis protein BMS1, putative.	0.999
108.t00021	368.t00004	C4M5T1	C4M0Q1	Nuclear complex protein 4, putative.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.856
108.t00021	39.t00016	C4M5T1	C4LWT5	Nuclear complex protein 4, putative.	BP28CT domain-containing protein.	0.999
108.t00021	484.t00001	C4M5T1	C4M7I9	Nuclear complex protein 4, putative.	WD domain containing protein.	0.999
108.t00021	60.t00003	C4M5T1	C4M3P7	Nuclear complex protein 4, putative.	WD domain containing protein.	0.992
108.t00021	70.t00019	C4M5T1	C4M085	Nuclear complex protein 4, putative.	U3 small nucleolar ribonucleoprotein protein IMP4, putative.	0.993
108.t00021	71.t00024	C4M5T1	C4M291	Nuclear complex protein 4, putative.	Uncharacterized protein.	0.774
108.t00021	74.t00033	C4M5T1	C4M3V4	Nuclear complex protein 4, putative.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.929
108.t00021	8.t00062	C4M5T1	C4LTX9	Nuclear complex protein 4, putative.	WD domain containing protein.	0.999
108.t00021	85.t00004	C4M5T1	C4LVK6	Nuclear complex protein 4, putative.	WD domain containing protein.	0.999
108.t00021	9.t00076	C4M5T1	C4M9H6	Nuclear complex protein 4, putative.	Nucleolar complex protein 2 homolog, putative.	0.941
108.t00021	90.t00020	C4M5T1	C4M5L0	Nuclear complex protein 4, putative.	WD domain containing protein.	0.999
108.t00021	EHI_048860	C4M5T1	B1N5H2	Nuclear complex protein 4, putative.	U3 small nucleolar ribonucleo protein protein MPP10, putative.	0.987
108.t00021	EHI_094780	C4M5T1	B1N4W4	Nuclear complex protein 4, putative.	Pescadillo homolog, putative.	0.856