STRINGSTRING
67.t00006 67.t00006 trf1 trf1 EHI_092330 EHI_092330 EHI_183060 EHI_183060 EHI_000690 EHI_000690 EHI_124360 EHI_124360 EHI_006680 EHI_006680 EHI_009820 EHI_009820 EHI_002010 EHI_002010 EHI_059310 EHI_059310 EHI_129630 EHI_129630 EHI_193660 EHI_193660 130.t00019 130.t00019 EHI_026890 EHI_026890 EHI_144170 EHI_144170 EHI_116940 EHI_116940 EHI_137470 EHI_137470 EHI_126430 EHI_126430 2.t00064 2.t00064 NADK NADK 24.t00027 24.t00027 64.t00037 64.t00037 3.t00004 3.t00004 3.t00076 3.t00076 72.t00020 72.t00020 72.t00013 72.t00013 10.t00076 10.t00076 10.t00022 10.t00022 183.t00017 183.t00017 8.t00042 8.t00042 150.t00007 150.t00007 81.t00015 81.t00015 25.t00031 25.t00031 50.t00031 50.t00031 204.t00006 204.t00006 35.t00002 35.t00002 92.t00027 92.t00027 300.t00001 300.t00001 405.t00007 405.t00007 12.t00063 12.t00063 12.t00016 12.t00016 200.t00008 200.t00008 23.t00005 23.t00005 34.t00022 34.t00022 39.t00053 39.t00053 129.t00030 129.t00030 27.t00035 27.t00035 37.t00009 37.t00009 169.t00023 169.t00023 17.t00046 17.t00046 17.t00052 17.t00052 402.t00001 402.t00001 172.t00013 172.t00013 55.t00018 55.t00018 taf1 taf1 62.t00030 62.t00030 62.t00003 62.t00003 47.t00024 47.t00024 38.t00039 38.t00039 415.t00006 415.t00006 64.t00020 64.t00020 7.t00016 7.t00016 131.t00025 131.t00025 30.t00023 30.t00023 103.t00019 103.t00019 178.t00011 178.t00011 53.t00034 53.t00034 53.t00026 53.t00026 114.t00014 114.t00014 180.t00010 180.t00010 4.t00129 4.t00129 153.t00017 153.t00017 68.t00035 68.t00035 7.t00062 7.t00062 264.t00008 264.t00008 246.t00005 246.t00005 50.t00036 50.t00036 1.t00023 1.t00023 33.t00032 33.t00032 198.t00003 198.t00003 102.t00005 102.t00005 40.t00010 40.t00010 41.t00010 41.t00010 310.t00009 310.t00009 128.t00016 128.t00016 409.t00002 409.t00002 8.t00003 8.t00003 187.t00011 187.t00011 82.t00003 82.t00003 139.t00020 139.t00020 110.t00025 110.t00025 341.t00004 341.t00004 137.t00010 137.t00010 162.t00003 162.t00003 112.t00012 112.t00012 1.t00012 1.t00012 1.t00017 1.t00017 59.t00015 59.t00015 113.t00005 113.t00005 73.t00023 73.t00023 26.t00064 26.t00064 217.t00016 217.t00016 51.t00007 51.t00007 51.t00031 51.t00031 171.t00022 171.t00022 193.t00007 193.t00007 202.t00012 202.t00012 115.t00027 115.t00027 42.t00042 42.t00042 56.t00005 56.t00005 170.t00025 170.t00025 254.t00012 254.t00012 90.t00031 90.t00031 197.t00012 197.t00012 59.t00027 59.t00027 59.t00030 59.t00030 297.t00005 297.t00005 293.t00010 293.t00010 293.t00011 293.t00011 375.t00005 375.t00005 222.t00013 222.t00013 288.t00002 288.t00002 366.t00004 366.t00004 161.t00010 161.t00010 296.t00004 296.t00004 344.t00001 344.t00001 292.t00013 292.t00013 281.t00001 281.t00001 138.t00017 138.t00017 121.t00002 121.t00002 369.t00002 369.t00002 72.t00027 72.t00027 95.t00021 95.t00021 528.t00001 528.t00001 14.t00057 14.t00057 279.t00017 279.t00017 121.t00014 121.t00014 TBP TBP RPB1 RPB1 20.t00034 20.t00034
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
67.t00006DNA-directed DNA polymerase, putative. (657 aa)
trf1TATA-box-binding protein-like protein 1; TATA box-binding transcription factor. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. (216 aa)
EHI_092330Coenzyme A biosynthesis bifunctional protein coaBC, putative. (397 aa)
EHI_183060Pantothenate kinase 1, putative. (403 aa)
EHI_000690Seryl-tRNA synthetase, putative. (251 aa)
EHI_124360Uncharacterized protein. (212 aa)
EHI_006680Phosphopantetheineadenylyltransferase, putative. (233 aa)
EHI_009820Myb-like DNA-binding domain containing protein. (182 aa)
EHI_002010Mannose-6-phosphate isomerase, putative. (241 aa)
EHI_059310Deoxyuridine 5'-triphosphate nucleotidohydrolase domain containing protein. (359 aa)
EHI_129630DNA primase small subunit, putative. (189 aa)
EHI_193660Deoxyuridine 5'-triphosphate nucleotidohydrolase domain containing protein. (359 aa)
130.t00019Nicotinamide-nucleotide adenylyltransferase. (212 aa)
EHI_026890Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, putative. (168 aa)
EHI_144170Uncharacterized protein. (310 aa)
EHI_116940Deoxyuridine 5'-triphosphate nucleotidohydrolase domain containing protein. (359 aa)
EHI_137470Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, putative. (254 aa)
EHI_126430Uncharacterized protein. (310 aa)
2.t00064DNA polymerase. (1132 aa)
NADKInorganic polyphosphate/ATP-NAD kinase, putative. (261 aa)
24.t00027RNA polymerase III subunit, putative. (499 aa)
64.t00037DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa)
3.t00004UMP-CMP kinase, putative; Belongs to the adenylate kinase family. (201 aa)
3.t00076Uncharacterized protein. (428 aa)
72.t00020Uncharacterized protein. (863 aa)
72.t00013Uncharacterized protein. (336 aa)
10.t00076Uncharacterized protein. (426 aa)
10.t00022DNA-directed RNA polymerase III subunit, putative. (236 aa)
183.t00017Uncharacterized protein. (284 aa)
8.t00042DNA polymerase. (1385 aa)
150.t00007HAD hydrolase, family IA, variant 3. (213 aa)
81.t00015DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1170 aa)
25.t00031Nicotinate phosphoribosyltransferase, putative. (390 aa)
50.t00031Uncharacterized protein. (1231 aa)
204.t00006Seryl-tRNA synthetase, putative. (453 aa)
35.t00002TFIIH basal transcription factor complex subunit, putative. (363 aa)
92.t00027snRNA activating protein complex subunit, putative. (327 aa)
300.t00001DNA primase; Belongs to the eukaryotic-type primase small subunit family. (380 aa)
405.t00007Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (159 aa)
12.t00063Uncharacterized protein. (559 aa)
12.t00016Transcription initiation factor SPT5, putative. (774 aa)
200.t00008RNA polymerase subunit Rpb5, putative. (204 aa)
23.t00005Dephospho-CoA kinase, putative. (204 aa)
34.t00022Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (158 aa)
39.t00053Transcription initiation factor TFIID subunit 5, putative. (360 aa)
129.t00030DNA primase large subunit, putative. (457 aa)
27.t00035DNA-directed RNA polymerase II subunit, putative. (180 aa)
37.t00009Adenosine deaminase, putative. (348 aa)
169.t00023RNA polymerases II subunit, putative. (112 aa)
17.t00046WD domain containing protein. (641 aa)
17.t00052Ribose-phosphate pyrophosphokinase, putative. (332 aa)
402.t00001CDC73_C domain-containing protein. (218 aa)
172.t00013Phosphoribulokinase/uridine kinase family protein. (393 aa)
55.t00018Thymidylate kinase, putative. (210 aa)
taf1Bromodomain protein, putative. (1163 aa)
62.t00030Negative cofactor 2-beta. (156 aa)
62.t00003Guanylate kinase, putative. (186 aa)
47.t00024Dr1-associated corepressor, putative. (119 aa)
38.t00039Nucleoside diphosphate kinase, putative. (211 aa)
415.t00006Uncharacterized protein. (310 aa)
64.t00020Protein kinase domain containing protein. (304 aa)
7.t00016DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
131.t00025NAD synthetase, putative. (306 aa)
30.t00023UDP-N-acetylglucosamine pyrophosphorylase, putative. (401 aa)
103.t00019Adenosine deaminase, putative. (337 aa)
178.t00011Uncharacterized protein. (549 aa)
53.t00034DNA polymerase. (1077 aa)
53.t00026Uncharacterized protein. (231 aa)
114.t00014Ribose-phosphate pyrophosphokinase, putative. (337 aa)
180.t00010Uncharacterized protein. (440 aa)
4.t00129DNA primase; Belongs to the eukaryotic-type primase small subunit family. (372 aa)
153.t00017Uncharacterized protein. (294 aa)
68.t00035Uncharacterized protein. (120 aa)
7.t00062General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (484 aa)
264.t00008Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity; Belongs to the adenylate kinase family. AK6 subfamily. (186 aa)
246.t00005Phosphoglucomutase/phosphomannomutase family protein. (454 aa)
50.t00036Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, putative. (397 aa)
1.t00023Uncharacterized protein. (201 aa)
33.t00032Uncharacterized protein. (321 aa)
198.t00003Transcription initiation factor IIIB chain BRF, putative. (546 aa)
102.t00005Uncharacterized protein. (1241 aa)
40.t00010DNA repair helicase, putative. (589 aa)
41.t00010DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1122 aa)
310.t00009DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1570 aa)
128.t00016Chromatin-specific transcription elongation factor, putative. (806 aa)
409.t00002Phosphoglucomutase/phosphomannomutase family protein; Belongs to the phosphohexose mutase family. (594 aa)
8.t00003Deoxycytidine triphosphate deaminase, putative. (171 aa)
187.t00011Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative. (142 aa)
82.t00003Uncharacterized protein. (168 aa)
139.t00020Phosphoribulokinase/uridine kinase family protein. (260 aa)
110.t00025AMP deaminase, putative. (1261 aa)
341.t00004Uncharacterized protein. (466 aa)
137.t00010PCI domain containing protein. (314 aa)
162.t00003DNA-directed RNA polymerase II subunit, putative. (283 aa)
112.t00012Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (825 aa)
1.t00012tRNA splicing endonuclease, putative. (1140 aa)
1.t00017DNA ligase. (685 aa)
59.t00015DNA-directed RNA polymerase subunit N, putative. (73 aa)
113.t00005TFIID subunit, putative. (174 aa)
73.t00023DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1379 aa)
26.t00064Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (243 aa)
217.t00016TPR repeat protein. (922 aa)
51.t00007DNA primase large subunit, putative. (523 aa)
51.t00031DNA-directed RNA polymerases I, II, and III 23 kDa, putative. (122 aa)
171.t00022RNA-dependent RNA polymerase. (1026 aa)
193.t00007Riboflavin kinase / FAD synthetase, putative. (131 aa)
202.t00012Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (764 aa)
115.t00027TATA-box-binding protein 2; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (212 aa)
42.t00042Inosine-uridine preferring nucleoside hydrolase, putative. (318 aa)
56.t00005AMP deaminase, putative. (1327 aa)
170.t00025Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (394 aa)
254.t00012Centromere/microtubule binding protein cbf5, putative. (484 aa)
90.t00031Phosphomannose isomerase, putative. (372 aa)
197.t00012DNA repair helicase, putative. (770 aa)
59.t00027DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa)
59.t00030Deoxycytidyl transferase, putative. (708 aa)
297.t00005DNA repair helicase, putative. (788 aa)
293.t000105'-3' exonuclease domain containing protein. (628 aa)
293.t00011Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (159 aa)
375.t00005Deoxyuridine 5'-triphosphate nucleotidohydrolase domain containing protein. (359 aa)
222.t00013TFIID subunit, putative. (433 aa)
288.t00002Uncharacterized protein. (158 aa)
366.t00004Uncharacterized protein. (171 aa)
161.t00010Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
296.t00004Adenylate kinase; Belongs to the adenylate kinase family. (193 aa)
344.t00001DNA-directed RNA polymerase II subunit, putative. (137 aa)
292.t00013Uncharacterized protein. (946 aa)
281.t00001DNA repair helicase, putative. (648 aa)
138.t00017UDP-N-acetylglucosamine pyrophosphorylase, putative. (401 aa)
121.t00002DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1106 aa)
369.t00002Phosphoribulokinase /uridine kinase family protein. (257 aa)
72.t00027Protein kinase, putative; Belongs to the protein kinase superfamily. (335 aa)
95.t00021Kinase, PfkB family. (327 aa)
528.t00001Uncharacterized protein. (861 aa)
14.t00057Uncharacterized protein. (194 aa)
279.t00017Uncharacterized protein. (151 aa)
121.t00014UMP-CMP kinase, putative; Belongs to the adenylate kinase family. (202 aa)
TBPTATA-box-binding protein 1; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (234 aa)
RPB1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1636 aa)
20.t00034Thymidine kinase. (218 aa)
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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