(42 nodes) Ribosome assembly network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	315.t00001	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (316 aa)
	79.t00027	40S ribosomal protein S14, putative; Belongs to the universal ribosomal protein uS11 family. (146 aa)
	EHI_092070	WD domain containing protein. (204 aa)
	EHI_038320	UPF0113 domain-containing protein. (59 aa)
	EHI_038310	60S ribosome subunit biogenesis protein NIP7, putative. (86 aa)
	611.t00001	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (183 aa)
	EHI_059540	Brix domain-containing protein 1, putative. (153 aa)
	EHI_185010	Ribosomal protein L10, putative. (210 aa)
	2.t00039	Uncharacterized protein. (246 aa)
	2.t00040	WD domain containing protein. (881 aa)
	6.t00003	40S ribosomal protein S27. (95 aa)
	127.t00006	40S ribosomal protein S27. (84 aa)
	64.t00024	40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family. (206 aa)
	132.t00002	60S ribosomal protein L10, putative. (210 aa)
	60.t00021	60S ribosomal protein L6, putative. (204 aa)
	16.t00022	Brix domain containing protein. (353 aa)
	215.t00013	60S ribosomal protein L5, putative. (286 aa)
	28.t00013	Ribosomal protein L23A, putative; Belongs to the universal ribosomal protein uL23 family. (121 aa)
	221.t00002	40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family. (205 aa)
	23.t00018	Elongation factor 2, putative. (880 aa)
	34.t00044	40S ribosomal protein S19, putative. (155 aa)
	155.t00010	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (226 aa)
	50.t00003	WD domain containing protein. (463 aa)
	78.t00003	60S ribosomal protein L6, putative. (204 aa)
	238.t00008	40S ribosomal protein S27. (84 aa)
	262.t00008	Ribosome biogenesis protein, putative. (291 aa)
	108.t00003	40S ribosomal protein S28, putative. (69 aa)
	201.t00012	40S ribosomal protein S28, putative. (69 aa)
	65.t00021	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family. (144 aa)
	116.t00010	Uncharacterized protein. (224 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (239 aa)
	63.t00023	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (183 aa)
	878.t00001	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (254 aa)
	213.t00002	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family. (144 aa)
	454.t00001	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family. (144 aa)
	115.t00005	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (258 aa)
	297.t00009	Ccaat-box-binding transcription factor, putative. (718 aa)
	4.t00068	60S ribosomal protein L6, putative. (204 aa)
	188.t00006	Uncharacterized protein. (245 aa)
	350.t00006	40S ribosomal protein S19, putative. (155 aa)
	289.t00009	Ribosome biogenesis protein, putative. (295 aa)
	447.t00009	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (225 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
108.t00003	127.t00006	C4LZQ8	C4LT66	40S ribosomal protein S28, putative.	40S ribosomal protein S27.	0.981
108.t00003	132.t00002	C4LZQ8	C4LTA0	40S ribosomal protein S28, putative.	60S ribosomal protein L10, putative.	0.938
108.t00003	155.t00010	C4LZQ8	C4LX57	40S ribosomal protein S28, putative.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.897
108.t00003	188.t00006	C4LZQ8	C4M9X0	40S ribosomal protein S28, putative.	Uncharacterized protein.	0.591
108.t00003	2.t00039	C4LZQ8	C4LSH8	40S ribosomal protein S28, putative.	Uncharacterized protein.	0.591
108.t00003	2.t00040	C4LZQ8	C4LSH9	40S ribosomal protein S28, putative.	WD domain containing protein.	0.957
108.t00003	201.t00012	C4LZQ8	C4M059	40S ribosomal protein S28, putative.	40S ribosomal protein S28, putative.	0.901
108.t00003	213.t00002	C4LZQ8	C4M7A5	40S ribosomal protein S28, putative.	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family.	0.979
108.t00003	215.t00013	C4LZQ8	C4LU56	40S ribosomal protein S28, putative.	60S ribosomal protein L5, putative.	0.993
108.t00003	221.t00002	C4LZQ8	C4LVZ6	40S ribosomal protein S28, putative.	40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family.	0.992
108.t00003	23.t00018	C4LZQ8	C4LWB7	40S ribosomal protein S28, putative.	Elongation factor 2, putative.	0.833
108.t00003	238.t00008	C4LZQ8	C4LYP4	40S ribosomal protein S28, putative.	40S ribosomal protein S27.	0.981
108.t00003	28.t00013	C4LZQ8	C4LV64	40S ribosomal protein S28, putative.	Ribosomal protein L23A, putative; Belongs to the universal ribosomal protein uL23 family.	0.990
108.t00003	315.t00001	C4LZQ8	B1N2Z3	40S ribosomal protein S28, putative.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.988
108.t00003	34.t00044	C4LZQ8	C4LWS0	40S ribosomal protein S28, putative.	40S ribosomal protein S19, putative.	0.992
108.t00003	350.t00006	C4LZQ8	C4MA13	40S ribosomal protein S28, putative.	40S ribosomal protein S19, putative.	0.992
108.t00003	4.t00068	C4LZQ8	C4M9F8	40S ribosomal protein S28, putative.	60S ribosomal protein L6, putative.	0.899
108.t00003	447.t00009	C4LZQ8	C4MAY8	40S ribosomal protein S28, putative.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.897
108.t00003	454.t00001	C4LZQ8	C4M7H3	40S ribosomal protein S28, putative.	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family.	0.979
108.t00003	6.t00003	C4LZQ8	C4LSR1	40S ribosomal protein S28, putative.	40S ribosomal protein S27.	0.981