(24 nodes) Identical protein binding network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	64.t00039	Uncharacterized protein. (171 aa)
	EHI_035060	Fumarate hydratase class I, anaerobic, putative. (188 aa)
	EHI_065310	Glycoprotein FP21, putative; Belongs to the SKP1 family. (160 aa)
	EHI_131670	Dynamin-1-like protein, putative. (214 aa)
	6.t00084	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (328 aa)
	78.t00022	Uncharacterized protein. (1117 aa)
	5.t00037	Myosin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2151 aa)
	129.t00005	Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (305 aa)
	282.t00012	Dynamin-1-like protein, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (682 aa)
	20.t00034	Thymidine kinase. (218 aa)
	62.t00027	Skp1 protein, putative; Belongs to the SKP1 family. (162 aa)
	200.t00005	Fumarate hydratase class I, anaerobic, putative. (206 aa)
	9.t00075	Arginine N-methyltransferase 1, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (319 aa)
	145.t00010	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (376 aa)
	109.t00002	Uncharacterized protein. (753 aa)
	11.t00027	J domain-containing protein. (2044 aa)
	154.t00006	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (663 aa)
	9.t00042	Uncharacterized protein. (2111 aa)
	181.t00006	Skp1 protein, putative; Belongs to the SKP1 family. (158 aa)
	19.t00065	SNF7 family protein. (204 aa)
	153.t00018	S-phase kinase-associated protein 1A, putative; Belongs to the SKP1 family. (158 aa)
	20.t00058	Uncharacterized protein. (1042 aa)
	53.t00023	Casein kinase, putative. (329 aa)
	7.t00025	Protein kinase domain containing protein; Belongs to the protein kinase superfamily. (366 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
129.t00005	145.t00010	C4LX01	C4M6A1	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.779
129.t00005	53.t00023	C4LX01	C4M0F3	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Casein kinase, putative.	0.905
129.t00005	7.t00025	C4LX01	C4LZQ1	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.906
145.t00010	129.t00005	C4M6A1	C4LX01	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.779
145.t00010	53.t00023	C4M6A1	C4M0F3	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Casein kinase, putative.	0.780
145.t00010	7.t00025	C4M6A1	C4LZQ1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.779
19.t00065	64.t00039	C4M1A5	C4LZE7	SNF7 family protein.	Uncharacterized protein.	0.978
53.t00023	129.t00005	C4M0F3	C4LX01	Casein kinase, putative.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.905
53.t00023	145.t00010	C4M0F3	C4M6A1	Casein kinase, putative.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.780
53.t00023	7.t00025	C4M0F3	C4LZQ1	Casein kinase, putative.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.903
64.t00039	19.t00065	C4LZE7	C4M1A5	Uncharacterized protein.	SNF7 family protein.	0.978
7.t00025	129.t00005	C4LZQ1	C4LX01	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	0.906
7.t00025	145.t00010	C4LZQ1	C4M6A1	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.779
7.t00025	53.t00023	C4LZQ1	C4M0F3	Protein kinase domain containing protein; Belongs to the protein kinase superfamily.	Casein kinase, putative.	0.903