(38 nodes) Plasma membrane invagination network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	79.t00005	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (803 aa)
	99.t00019	14-3-3 protein 1; Belongs to the 14-3-3 family. (239 aa)
	8.t00018	Rho family GTPase. (193 aa)
	52.t00026	Rho family GTPase. (215 aa)
	146.t00004	Rho family GTPase. (201 aa)
	108.t00028	Rho family GTPase. (194 aa)
	97.t00016	Rho family GTPase. (196 aa)
	213.t00015	Inositol polyphosphate-5-phosphatase, putative. (920 aa)
	213.t00008	Rho family GTPase. (197 aa)
	183.t00010	Inositol polyphosphate 5-phosphatase, putative. (675 aa)
	197.t00011	Rho family GTPase. (195 aa)
	54.t00039	Coronin; Belongs to the WD repeat coronin family. (433 aa)
	296.t00006	Rho family GTPase. (199 aa)
	165.t00011	Rho family GTPase. (198 aa)
	281.t00003	Inositol polyphosphate 5-phosphatase, putative. (797 aa)
	110.t00006	Rho family GTPase. (202 aa)
	395.t00002	Rho family GTPase. (200 aa)
	105.t00023	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (871 aa)
	68.t00040	Coronin; Belongs to the WD repeat coronin family. (457 aa)
	110.t00017	Rho family GTPase. (215 aa)
	53.t00022	14-3-3 protein 3; Belongs to the 14-3-3 family. (240 aa)
	46.t00027	Rho family GTPase. (211 aa)
	18.t00037	WD repeat protein. (595 aa)
	77.t00022	14-3-3 protein 2; Belongs to the 14-3-3 family. (238 aa)
	14.t00047	Rho family GTPase. (199 aa)
	256.t00004	Inositol polyphosphate 5-phosphatase, putative. (676 aa)
	15.t00058	Rho family GTPase. (202 aa)
	16.t00017	Rho family GTPase. (200 aa)
	13.t00027	Inositol polyphosphate 5-phosphatase, putative. (764 aa)
	13.t00030	Rho family GTPase. (199 aa)
	150.t00004	Rac-like GTP-binding protein RAC2, putative. (239 aa)
	EHI_016010	66 kDa stress protein, putative. (223 aa)
	EHI_031740	RAS-related protein racG, putative. (197 aa)
	EHI_018960	Small GTPase RhoQ, putative. (102 aa)
	EHI_142190	WD repeat protein 2, putative. (590 aa)
	33.t00005	Calreticulin. (389 aa)
	71.t00025	Rho family GTPase. (194 aa)
	306.t00002	Inositol polyphosphate 5-phosphatase, putative. (970 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
105.t00023	79.t00005	C4M169	C4M2Z1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.903
108.t00028	53.t00022	C4M5T0	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.422
108.t00028	77.t00022	C4M5T0	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.424
108.t00028	99.t00019	C4M5T0	C4M323	Rho family GTPase.	14-3-3 protein 1; Belongs to the 14-3-3 family.	0.424
110.t00006	53.t00022	C4MA80	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.414
110.t00006	77.t00022	C4MA80	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.416
110.t00006	99.t00019	C4MA80	C4M323	Rho family GTPase.	14-3-3 protein 1; Belongs to the 14-3-3 family.	0.410
110.t00017	52.t00026	C4M0Y0	C4M4W4	Rho family GTPase.	Rho family GTPase.	0.801
110.t00017	53.t00022	C4M0Y0	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.410
110.t00017	77.t00022	C4M0Y0	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.410
110.t00017	99.t00019	C4M0Y0	C4M323	Rho family GTPase.	14-3-3 protein 1; Belongs to the 14-3-3 family.	0.410
13.t00027	256.t00004	C4LSE0	C4LX62	Inositol polyphosphate 5-phosphatase, putative.	Inositol polyphosphate 5-phosphatase, putative.	0.912
13.t00030	53.t00022	C4LSD7	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.410
13.t00030	77.t00022	C4LSD7	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.410
13.t00030	99.t00019	C4LSD7	C4M323	Rho family GTPase.	14-3-3 protein 1; Belongs to the 14-3-3 family.	0.410
14.t00047	53.t00022	C4LX92	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.422
14.t00047	77.t00022	C4LX92	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.432
14.t00047	99.t00019	C4LX92	C4M323	Rho family GTPase.	14-3-3 protein 1; Belongs to the 14-3-3 family.	0.424
146.t00004	53.t00022	C4M5Q7	C4M0F4	Rho family GTPase.	14-3-3 protein 3; Belongs to the 14-3-3 family.	0.421
146.t00004	77.t00022	C4M5Q7	C4LXB1	Rho family GTPase.	14-3-3 protein 2; Belongs to the 14-3-3 family.	0.425