(71 nodes) Rho GTPase-activating protein domain network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	33.t00031	Uncharacterized protein. (756 aa)
	EHI_110800	RhoGAP domain containing protein. (179 aa)
	EHI_155690	RhoGAP domain containing protein. (479 aa)
	EHI_159720	RhoGAP domain containing protein. (282 aa)
	EHI_174060	Uncharacterized protein. (116 aa)
	EHI_163460	Uncharacterized protein. (152 aa)
	EHI_131960	Uncharacterized protein. (206 aa)
	EHI_072080	RhoGAP domain containing protein. (534 aa)
	EHI_056130	RhoGAP domain containing protein. (358 aa)
	EHI_055340	RhoGAP domain containing protein. (446 aa)
	EHI_094820	RhoGAP domain containing protein. (174 aa)
	13.t00060	RhoGAP domain containing protein. (548 aa)
	13.t00027	Inositol polyphosphate 5-phosphatase, putative. (764 aa)
	2.t00101	RhoGAP domain containing protein. (1067 aa)
	1.t00113	Uncharacterized protein. (676 aa)
	1.t00071	RhoGAP domain containing protein. (438 aa)
	1.t00057	RhoGAP domain containing protein. (552 aa)
	3.t00125	RhoGAP domain containing protein. (387 aa)
	3.t00079	RhoGAP domain containing protein. (769 aa)
	31.t00008	RhoGAP domain containing protein. (1088 aa)
	61.t00043	RhoGAP domain containing protein. (577 aa)
	61.t00035	Uncharacterized protein. (868 aa)
	272.t00008	RhoGAP domain containing protein. (565 aa)
	21.t00042	RhoGAP domain containing protein. (645 aa)
	81.t00007	RhoGAP domain containing protein. (593 aa)
	204.t00005	Rho GTPase activating protein, putative. (471 aa)
	35.t00007	RhoGAP domain containing protein. (934 aa)
	951.t00001	RhoGAP domain containing protein. (509 aa)
	246.t00012	RhoGAP domain containing protein. (424 aa)
	258.t00008	RhoGAP domain containing protein. (301 aa)
	281.t00003	Inositol polyphosphate 5-phosphatase, putative. (797 aa)
	350.t00002	Rho GTPase activating protein, putative. (591 aa)
	140.t00006	RhoGAP domain containing protein. (507 aa)
	9.t00002	RhoGAP domain containing protein. (436 aa)
	92.t00012	RhoGAP domain containing protein. (428 aa)
	12.t00032	Rho GTPase activating protein, putative. (894 aa)
	6.t00042	RhoGAP domain containing protein. (324 aa)
	32.t00032	RhoGAP domain containing protein. (595 aa)
	32.t00031	Rho GTPase activating protein, putative. (366 aa)
	87.t00024	RhoGAP domain containing protein. (386 aa)
	88.t00024	RhoGAP domain containing protein. (606 aa)
	256.t00004	Inositol polyphosphate 5-phosphatase, putative. (676 aa)
	14.t00028	RhoGAP domain containing protein. (474 aa)
	77.t00023	RhoGAP domain containing protein. (370 aa)
	283.t00013	RhoGAP domain containing protein. (304 aa)
	37.t00021	RhoGAP domain containing protein. (360 aa)
	20.t00066	RhoGAP domain containing protein. (362 aa)
	17.t00058	RhoGAP domain containing protein. (449 aa)
	18.t00030	RhoGAP domain containing protein. (362 aa)
	7.t00049	RhoGAP domain containing protein. (549 aa)
	34.t00049	RhoGAP domain containing protein. (440 aa)
	379.t00003	RhoGAP domain containing protein. (503 aa)
	254.t00015	RhoGAP domain containing protein. (239 aa)
	367.t00001	Rho GTPase activating protein, putative. (541 aa)
	213.t00015	Inositol polyphosphate-5-phosphatase, putative. (920 aa)
	45.t00002	RhoGAP domain containing protein. (443 aa)
	202.t00011	Rho GTPase activating protein, putative. (694 aa)
	321.t00002	RhoGAP domain containing protein. (279 aa)
	157.t00016	RhoGAP domain containing protein. (509 aa)
	112.t00014	Rho GTPase activating protein, putative. (634 aa)
	233.t00022	RhoGAP domain containing protein. (529 aa)
	63.t00016	Uncharacterized protein. (1094 aa)
	185.t00014	RhoGAP domain containing protein. (214 aa)
	8.t00026	RhoGAP domain containing protein. (278 aa)
	218.t00015	RhoGAP domain containing protein. (374 aa)
	199.t00005	RhoGAP domain containing protein. (413 aa)
	126.t00010	Uncharacterized protein. (649 aa)
	94.t00021	Ras guanine nucleotide exchange factor, putative. (1246 aa)
	306.t00002	Inositol polyphosphate 5-phosphatase, putative. (970 aa)
	198.t00009	RhoGAP domain containing protein. (464 aa)
	127.t00008	RhoGAP domain containing protein. (569 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00057	233.t00022	C4LT64	C4M4N5	RhoGAP domain containing protein.	RhoGAP domain containing protein.	0.415
1.t00057	31.t00008	C4LT64	C4LTP1	RhoGAP domain containing protein.	RhoGAP domain containing protein.	0.415
1.t00057	33.t00031	C4LT64	C4M2B5	RhoGAP domain containing protein.	Uncharacterized protein.	0.415
1.t00057	63.t00016	C4LT64	C4M4L1	RhoGAP domain containing protein.	Uncharacterized protein.	0.421
112.t00014	18.t00030	C4M5E9	C4LZ06	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.568
112.t00014	185.t00014	C4M5E9	C4M4A0	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.579
112.t00014	198.t00009	C4M5E9	C4M2C8	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.450
112.t00014	199.t00005	C4M5E9	C4M3H0	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.450
112.t00014	204.t00005	C4M5E9	C4LV25	Rho GTPase activating protein, putative.	Rho GTPase activating protein, putative.	0.575
112.t00014	233.t00022	C4M5E9	C4M4N5	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.760
112.t00014	31.t00008	C4M5E9	C4LTP1	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.760
112.t00014	321.t00002	C4M5E9	C4M6N8	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.428
112.t00014	33.t00031	C4M5E9	C4M2B5	Rho GTPase activating protein, putative.	Uncharacterized protein.	0.760
112.t00014	61.t00043	C4M5E9	C4LU24	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.437
112.t00014	63.t00016	C4M5E9	C4M4L1	Rho GTPase activating protein, putative.	Uncharacterized protein.	0.762
112.t00014	8.t00026	C4M5E9	C4M476	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.428
112.t00014	81.t00007	C4M5E9	C4LUJ9	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.428
112.t00014	87.t00024	C4M5E9	C4LWV4	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.568
112.t00014	EHI_094820	C4M5E9	B1N4W8	Rho GTPase activating protein, putative.	RhoGAP domain containing protein.	0.428
127.t00008	233.t00022	C4M1Y8	C4M4N5	RhoGAP domain containing protein.	RhoGAP domain containing protein.	0.427