(49 nodes) Thioredoxin-like superfamily network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	5.t00007	Thioredoxin, putative. (504 aa)
	EHI_175280	Uncharacterized protein. (510 aa)
	EHI_117690	Uncharacterized protein. (126 aa)
	EHI_123390	Peroxiredoxin. (237 aa)
	EHI_157790	Viral IAP-associated factor homolog, putative. (158 aa)
	EHI_084260	Peroxiredoxin, putative. (250 aa)
	EHI_121620	Peroxiredoxin, putative. (133 aa)
	EHI_018740	Peroxiredoxin family protein. (132 aa)
	EHI_139570	Peroxiredoxin, putative. (192 aa)
	6.t00070	Thioredoxin, putative. (121 aa)
	1.t00119	Uncharacterized protein. (153 aa)
	3.t00064	Thioredoxin, putative. (485 aa)
	3.t00063	DIM1 family protein, putative. (142 aa)
	61.t00017	Thioredoxin, putative. (244 aa)
	81.t00008	Uncharacterized protein. (319 aa)
	81.t00029	Thioredoxin, putative. (244 aa)
	9.t00016	Uncharacterized protein. (128 aa)
	28.t00023	Peroxiredoxin family protein. (208 aa)
	9.t00021	Uncharacterized protein. (531 aa)
	6.t00016	Thioredoxin; Belongs to the thioredoxin family. (114 aa)
	233.t00005	Uncharacterized protein. (101 aa)
	8.t00082	Thioredoxin; Belongs to the thioredoxin family. (103 aa)
	38.t00025	Phosducin-like protein. (250 aa)
	42.t00029	Thioredoxin, putative. (125 aa)
	253.t00005	Thioredoxin, putative. (379 aa)
	53.t00033	Thioredoxin, putative. (150 aa)
	29.t00021	Thioredoxin, putative. (339 aa)
	212.t00014	Thioredoxin, putative. (106 aa)
	1.t00031	Thioredoxin, putative. (300 aa)
	177.t00017	Thioredoxin, putative. (163 aa)
	828.t00001	Peroxiredoxin, putative. (233 aa)
	30.t00049	Thioredoxin, putative; Belongs to the protein disulfide isomerase family. (127 aa)
	82.t00018	Thioredoxin domain-containing protein. (495 aa)
	111.t00006	Thioredoxin, putative. (144 aa)
	136.t00007	Peroxiredoxin. (234 aa)
	186.t00012	Thioredoxin, putative. (119 aa)
	407.t00004	Uncharacterized protein. (209 aa)
	407.t00008	Phosducin-like protein. (221 aa)
	275.t00007	Uncharacterized protein. (415 aa)
	298.t00001	Peroxiredoxin, putative. (233 aa)
	270.t00007	Thioredoxin, putative. (105 aa)
	9.t00083	Thioredoxin, putative. (112 aa)
	271.t00010	Thioredoxin, putative. (605 aa)
	175.t00023	Uncharacterized protein. (563 aa)
	294.t00003	Peroxiredoxin. (229 aa)
	289.t00002	Thioredoxin, putative. (107 aa)
	206.t00013	Protein disulfide isomerase, putative; Belongs to the protein disulfide isomerase family. (368 aa)
	41.t00027	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	94.t00032	Peroxiredoxin, putative. (237 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
1.t00031	136.t00007	C4M1U3	C4M6Q4	Thioredoxin, putative.	Peroxiredoxin.	0.500
1.t00031	186.t00012	C4M1U3	C4M7K9	Thioredoxin, putative.	Thioredoxin, putative.	0.458
1.t00031	28.t00023	C4M1U3	C4LV91	Thioredoxin, putative.	Peroxiredoxin family protein.	0.500
1.t00031	294.t00003	C4M1U3	C4MAR7	Thioredoxin, putative.	Peroxiredoxin.	0.500
1.t00031	298.t00001	C4M1U3	C4M8W7	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
1.t00031	3.t00064	C4M1U3	C4LTD8	Thioredoxin, putative.	Thioredoxin, putative.	0.458
1.t00031	5.t00007	C4M1U3	C4LU87	Thioredoxin, putative.	Thioredoxin, putative.	0.458
1.t00031	82.t00018	C4M1U3	C4M611	Thioredoxin, putative.	Thioredoxin domain-containing protein.	0.458
1.t00031	828.t00001	C4M1U3	C4M3Q0	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
1.t00031	9.t00021	C4M1U3	C4LVA3	Thioredoxin, putative.	Uncharacterized protein.	0.458
1.t00031	94.t00032	C4M1U3	C4MBP3	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
1.t00031	EHI_018740	C4M1U3	B1N617	Thioredoxin, putative.	Peroxiredoxin family protein.	0.500
1.t00031	EHI_084260	C4M1U3	B1N5L9	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
1.t00031	EHI_121620	C4M1U3	B1N5Y9	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
1.t00031	EHI_123390	C4M1U3	B1N5A8	Thioredoxin, putative.	Peroxiredoxin.	0.500
1.t00031	EHI_139570	C4M1U3	B1N623	Thioredoxin, putative.	Peroxiredoxin, putative.	0.500
111.t00006	136.t00007	C4M658	C4M6Q4	Thioredoxin, putative.	Peroxiredoxin.	0.540
111.t00006	28.t00023	C4M658	C4LV91	Thioredoxin, putative.	Peroxiredoxin family protein.	0.547
111.t00006	294.t00003	C4M658	C4MAR7	Thioredoxin, putative.	Peroxiredoxin.	0.540
111.t00006	298.t00001	C4M658	C4M8W7	Thioredoxin, putative.	Peroxiredoxin, putative.	0.540