STRINGSTRING
168.t00014 168.t00014 EHI_141400 EHI_141400 EHI_013040 EHI_013040 EHI_014390 EHI_014390 EHI_124560 EHI_124560 EHI_173180 EHI_173180 EHI_083430 EHI_083430 EHI_089880 EHI_089880 EHI_075040 EHI_075040 EHI_158840 EHI_158840 1.t00138 1.t00138 72.t00009 72.t00009 21.t00044 21.t00044 250.t00004 250.t00004 200.t00013 200.t00013 337.t00006 337.t00006 8.t00080 8.t00080 47.t00017 47.t00017 578.t00005 578.t00005 91.t00015 91.t00015 86.t00004 86.t00004 86.t00003 86.t00003 46.t00033 46.t00033 75.t00003 75.t00003 34.t00015 34.t00015 177.t00006 177.t00006 107.t00001 107.t00001 377.t00003 377.t00003 256.t00009 256.t00009 94.t00027 94.t00027 159.t00011 159.t00011 66.t00035 66.t00035 82.t00022 82.t00022 315.t00007 315.t00007 698.t00002 698.t00002 1.t00046 1.t00046 51.t00032 51.t00032 518.t00002 518.t00002 168.t00008 168.t00008 264.t00015 264.t00015 98.t00012 98.t00012 134.t00029 134.t00029 186.t00007 186.t00007 479.t00006 479.t00006 3.t00070 3.t00070 300.t00003 300.t00003 4.t00004 4.t00004 15.t00050 15.t00050 57.t00026 57.t00026 EHI_135430 EHI_135430 404.t00001 404.t00001 72.t00024 72.t00024 13.t00051 13.t00051 287.t00007 287.t00007 261.t00008 261.t00008 322.t00004 322.t00004 8.t00002 8.t00002
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
168.t00014Adaptor protein (AP) family protein. (874 aa)
EHI_141400Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (330 aa)
EHI_013040Adaptor protein (AP) family protein. (1091 aa)
EHI_014390AP-2 complex protein, putative. (582 aa)
EHI_124560AP-2 complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (414 aa)
EHI_173180Coatomer subunit beta, putative. (406 aa)
EHI_083430Adapter-related protein complex 3 (AP-3) subunit, putative. (855 aa)
EHI_089880AP-1 complex subunit mu-2, putative; Belongs to the adaptor complexes medium subunit family. (320 aa)
EHI_075040GTP-binding protein; Belongs to the small GTPase superfamily. SAR1 family. (190 aa)
EHI_158840AP-3 complex subunit delta-1, putative. (111 aa)
1.t00138GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (219 aa)
72.t00009Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (359 aa)
21.t00044Adaptor protein (AP) family protein. (735 aa)
250.t00004AP-1 complex subunit gamma. (837 aa)
200.t00013Exocyst subunit Exo70 family protein; Component of the exocyst complex. (765 aa)
337.t00006Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (209 aa)
8.t00080Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (348 aa)
47.t00017Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (730 aa)
578.t0000560S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (411 aa)
91.t00015Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (163 aa)
86.t00004Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (218 aa)
86.t00003Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (296 aa)
46.t00033Autophagy-related protein 3. (268 aa)
75.t00003Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (177 aa)
34.t00015AP-3 complex subunit delta. (1030 aa)
177.t00006Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (227 aa)
107.t00001Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (973 aa)
377.t00003GTP-binding protein; Belongs to the small GTPase superfamily. SAR1 family. (190 aa)
256.t00009Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (170 aa)
94.t00027MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (393 aa)
159.t00011Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (504 aa)
66.t00035Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (848 aa)
82.t00022Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (533 aa)
315.t00007Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (726 aa)
698.t00002Protein transport protein Sec24, putative. (876 aa)
1.t00046Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (843 aa)
51.t00032Coatomer beta subunit, putative. (910 aa)
518.t00002Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (844 aa)
168.t00008Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (325 aa)
264.t00015Sec 13 protein, putative; Belongs to the WD repeat SEC13 family. (261 aa)
98.t00012Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (721 aa)
134.t00029Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (346 aa)
186.t00007ER lumen protein-retaining receptor. (214 aa)
479.t00006Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (186 aa)
3.t00070AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
300.t00003AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
4.t00004AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (146 aa)
15.t00050AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (149 aa)
57.t00026Clathrin-adaptor medium chain, putative; Belongs to the adaptor complexes medium subunit family. (426 aa)
EHI_135430Clathrin coat assembly protein, putative; Belongs to the adaptor complexes medium subunit family. (407 aa)
404.t00001AP-1 complex subunit mu-2, putative; Belongs to the adaptor complexes medium subunit family. (427 aa)
72.t00024AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (862 aa)
13.t00051AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (908 aa)
287.t00007AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (961 aa)
261.t00008AP-1 complex subunit gamma. (855 aa)
322.t00004AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (724 aa)
8.t00002Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (800 aa)
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.