(23 nodes) Pyruvate metabolism and Citric Acid (TCA) cycle network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EHI_014030	NAD(P) transhydrogenase subunit alpha, putative. (1083 aa)
	425.t00002	Malic enzyme, putative. (487 aa)
	EHI_050330	Malic enzyme, putative. (487 aa)
	EHI_024240	Aldehyde-alcohol dehydrogenase 2, putative. (829 aa)
	EHI_161010	Anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative. (573 aa)
	EHI_030180	Alcohol dehydrogenase 3, putative. (98 aa)
	EHI_082270	Aspartate ammonia-lyase, putative. (177 aa)
	EHI_055400	Uncharacterized protein. (1098 aa)
	EHI_160670	Alcohol dehydrogenase 3, putative. (222 aa)
	31.t00001	Metallo-beta-lactamase family protein. (214 aa)
	61.t00038	Metallo-beta-lactamase family protein. (217 aa)
	15.t00026	Acetyl-CoA synthetase, putative. (713 aa)
	221.t00019	Alcohol dehydrogenase, putative. (383 aa)
	34.t00053	Alcohol dehydrogenase 3, putative. (384 aa)
	106.t00017	Alcohol dehydrogenase, putative. (360 aa)
	22.t00031	Aspartate ammonia-lyase, putative. (472 aa)
	69.t00027	Alcohol dehydrogenase, putative. (382 aa)
	124.t00001	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (870 aa)
	22.t00022	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (870 aa)
	90.t00017	Pyridine nucleotide transhydrogenase beta subunit, putative. (462 aa)
	285.t00008	NAD(FAD)-dependent dehydrogenase, putative. (1066 aa)
	346.t00002	Alcohol dehydrogenase, putative. (382 aa)
	125.t00017	Alcohol dehydrogenase, putative. (419 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
106.t00017	425.t00002	C4LZ92	Q9NH04	Alcohol dehydrogenase, putative.	Malic enzyme, putative.	0.406
106.t00017	EHI_050330	C4LZ92	B1N2J0	Alcohol dehydrogenase, putative.	Malic enzyme, putative.	0.406
124.t00001	22.t00022	C4M230	C4M2R2	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.900
124.t00001	425.t00002	C4M230	Q9NH04	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Malic enzyme, putative.	0.515
124.t00001	EHI_024240	C4M230	B1N387	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Aldehyde-alcohol dehydrogenase 2, putative.	0.900
124.t00001	EHI_050330	C4M230	B1N2J0	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Malic enzyme, putative.	0.406
125.t00017	425.t00002	C4M7F5	Q9NH04	Alcohol dehydrogenase, putative.	Malic enzyme, putative.	0.540
125.t00017	EHI_050330	C4M7F5	B1N2J0	Alcohol dehydrogenase, putative.	Malic enzyme, putative.	0.406
125.t00017	EHI_161010	C4M7F5	B1N3H7	Alcohol dehydrogenase, putative.	Anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative.	0.401
15.t00026	22.t00031	C4LUV9	C4M220	Acetyl-CoA synthetase, putative.	Aspartate ammonia-lyase, putative.	0.867
15.t00026	285.t00008	C4LUV9	C4M6H3	Acetyl-CoA synthetase, putative.	NAD(FAD)-dependent dehydrogenase, putative.	0.661
15.t00026	425.t00002	C4LUV9	Q9NH04	Acetyl-CoA synthetase, putative.	Malic enzyme, putative.	0.905
15.t00026	EHI_050330	C4LUV9	B1N2J0	Acetyl-CoA synthetase, putative.	Malic enzyme, putative.	0.878
15.t00026	EHI_082270	C4LUV9	B1N3V9	Acetyl-CoA synthetase, putative.	Aspartate ammonia-lyase, putative.	0.866
15.t00026	EHI_161010	C4LUV9	B1N3H7	Acetyl-CoA synthetase, putative.	Anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative.	0.729
22.t00022	124.t00001	C4M2R2	C4M230	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.900
22.t00022	425.t00002	C4M2R2	Q9NH04	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Malic enzyme, putative.	0.406
22.t00022	EHI_024240	C4M2R2	B1N387	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Aldehyde-alcohol dehydrogenase 2, putative.	0.900
22.t00022	EHI_050330	C4M2R2	B1N2J0	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Malic enzyme, putative.	0.406
22.t00031	15.t00026	C4M220	C4LUV9	Aspartate ammonia-lyase, putative.	Acetyl-CoA synthetase, putative.	0.867