(22 nodes) (2022) Host-parasite interactions in infections due to Entamoeba histolytica: A tale of known and unknown. network (Entamoeba histolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	9.t00061	Fe-hydrogenase, putative. (468 aa)
	77.t00031	Beta-amylase. (444 aa)
	384.t00003	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (190 aa)
	EHI_139570	Peroxiredoxin, putative. (192 aa)
	EHI_121620	Peroxiredoxin, putative. (133 aa)
	EHI_084260	Peroxiredoxin, putative. (250 aa)
	EHI_123390	Peroxiredoxin. (237 aa)
	EHI_160670	Alcohol dehydrogenase 3, putative. (222 aa)
	EHI_120360	Grainin, putative. (215 aa)
	EHI_058340	Beta-amylase. (437 aa)
	EHI_030180	Alcohol dehydrogenase 3, putative. (98 aa)
	1.t00075	Beta-amylase. (437 aa)
	103.t00038	Putative long iron-dependent hydrogenase 2; Belongs to the NARF family. (504 aa)
	94.t00032	Peroxiredoxin, putative. (237 aa)
	294.t00003	Peroxiredoxin. (229 aa)
	442.t00004	Peroxiredoxin. (233 aa)
	298.t00001	Peroxiredoxin, putative. (233 aa)
	136.t00007	Peroxiredoxin. (234 aa)
	89.t00012	Grainin, putative. (215 aa)
	828.t00001	Peroxiredoxin, putative. (233 aa)
	69.t00017	Beta-amylase. (436 aa)
	261.t00004	Beta-amylase. (436 aa)

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
136.t00007	384.t00003	C4M6Q4	C4LX20	Peroxiredoxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
294.t00003	384.t00003	C4MAR7	C4LX20	Peroxiredoxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
298.t00001	384.t00003	C4M8W7	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
384.t00003	136.t00007	C4LX20	C4M6Q4	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin.	0.774
384.t00003	294.t00003	C4LX20	C4MAR7	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin.	0.774
384.t00003	298.t00001	C4LX20	C4M8W7	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.774
384.t00003	442.t00004	C4LX20	C4MA54	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin.	0.774
384.t00003	828.t00001	C4LX20	C4M3Q0	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.774
384.t00003	94.t00032	C4LX20	C4MBP3	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.774
384.t00003	EHI_084260	C4LX20	B1N5L9	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.774
384.t00003	EHI_121620	C4LX20	B1N5Y9	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.776
384.t00003	EHI_123390	C4LX20	B1N5A8	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin.	0.774
384.t00003	EHI_139570	C4LX20	B1N623	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Peroxiredoxin, putative.	0.774
442.t00004	384.t00003	C4MA54	C4LX20	Peroxiredoxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
828.t00001	384.t00003	C4M3Q0	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
94.t00032	384.t00003	C4MBP3	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
EHI_084260	384.t00003	B1N5L9	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
EHI_121620	384.t00003	B1N5Y9	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.776
EHI_123390	384.t00003	B1N5A8	C4LX20	Peroxiredoxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774
EHI_139570	384.t00003	B1N623	C4LX20	Peroxiredoxin, putative.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.774