(27 nodes) Ribosomal protein S5 domain 2-type fold, subgroup network (Naegleria gruberi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D2W515_NAEGR	Predicted protein. (246 aa)
	D2W640_NAEGR	Predicted protein. (246 aa)
	D2VIA4_NAEGR	Elongation factor G. (679 aa)
	D2W213_NAEGR	Elongation factor G, domain IV. (782 aa)
	D2VVK5_NAEGR	Predicted protein. (662 aa)
	D2VUK9_NAEGR	Predicted protein. (854 aa)
	D2VU26_NAEGR	Predicted protein. (397 aa)
	D2VT59_NAEGR	Ribosomal_S9 domain-containing protein; Belongs to the universal ribosomal protein uS9 family. (674 aa)
	D2VSM3_NAEGR	Elongation factor 2. (854 aa)
	D2VSK3_NAEGR	Elongation factor 2. (854 aa)
	D2VSB8_NAEGR	Tr-type G domain-containing protein. (1049 aa)
	D2VMW0_NAEGR	Translation elongation factor 2. (837 aa)
	D2VH24_NAEGR	Predicted protein. (486 aa)
	D2VJC9_NAEGR	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (616 aa)
	D2VH01_NAEGR	Translation elongation factor 2. (854 aa)
	D2VDX6_NAEGR	Lon protease homolog; Belongs to the peptidase S16 family. (1007 aa)
	D2VDQ7_NAEGR	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (730 aa)
	D2VAA0_NAEGR	Predicted protein. (753 aa)
	D2VA51_NAEGR	Predicted protein. (995 aa)
	D2V9S8_NAEGR	Mevalonate kinase. (434 aa)
	D2V5K5_NAEGR	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1135 aa)
	D2V235_NAEGR	Elongation factor 2. (830 aa)
	D2V160_NAEGR	40S ribosomal protein S16. (142 aa)
	NAEGRDRAFT_395	Predicted protein. (718 aa)
	D2UZM0_NAEGR	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1457 aa)
	D2UXJ7_NAEGR	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (280 aa)
	D2W352_NAEGR	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (391 aa)

Your Current Organism:

Naegleria gruberi

NCBI taxonomy Id: 5762
Other names: N. gruberi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D2UXJ7_NAEGR	D2V160_NAEGR	D2UXJ7	D2V160	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	40S ribosomal protein S16.	0.999
D2UXJ7_NAEGR	D2V235_NAEGR	D2UXJ7	D2V235	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor 2.	0.830
D2UXJ7_NAEGR	D2VA51_NAEGR	D2UXJ7	D2VA51	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Predicted protein.	0.768
D2UXJ7_NAEGR	D2VAA0_NAEGR	D2UXJ7	D2VAA0	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Predicted protein.	0.830
D2UXJ7_NAEGR	D2VDQ7_NAEGR	D2UXJ7	D2VDQ7	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.866
D2UXJ7_NAEGR	D2VH01_NAEGR	D2UXJ7	D2VH01	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Translation elongation factor 2.	0.830
D2UXJ7_NAEGR	D2VIA4_NAEGR	D2UXJ7	D2VIA4	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor G.	0.568
D2UXJ7_NAEGR	D2VMW0_NAEGR	D2UXJ7	D2VMW0	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Translation elongation factor 2.	0.830
D2UXJ7_NAEGR	D2VSB8_NAEGR	D2UXJ7	D2VSB8	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Tr-type G domain-containing protein.	0.768
D2UXJ7_NAEGR	D2VSK3_NAEGR	D2UXJ7	D2VSK3	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor 2.	0.830
D2UXJ7_NAEGR	D2VSM3_NAEGR	D2UXJ7	D2VSM3	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor 2.	0.830
D2UXJ7_NAEGR	D2VT59_NAEGR	D2UXJ7	D2VT59	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Ribosomal_S9 domain-containing protein; Belongs to the universal ribosomal protein uS9 family.	0.994
D2UXJ7_NAEGR	D2VUK9_NAEGR	D2UXJ7	D2VUK9	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Predicted protein.	0.830
D2UXJ7_NAEGR	D2W213_NAEGR	D2UXJ7	D2W213	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Elongation factor G, domain IV.	0.830
D2UXJ7_NAEGR	D2W515_NAEGR	D2UXJ7	D2W515	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Predicted protein.	0.830
D2UXJ7_NAEGR	NAEGRDRAFT_395	D2UXJ7	D2V030	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	Predicted protein.	0.830
D2UZM0_NAEGR	D2VDX6_NAEGR	D2UZM0	D2VDX6	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Lon protease homolog; Belongs to the peptidase S16 family.	0.436
D2UZM0_NAEGR	D2VIA4_NAEGR	D2UZM0	D2VIA4	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor G.	0.529
D2UZM0_NAEGR	D2VSB8_NAEGR	D2UZM0	D2VSB8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Tr-type G domain-containing protein.	0.478
D2UZM0_NAEGR	D2VT59_NAEGR	D2UZM0	D2VT59	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ribosomal_S9 domain-containing protein; Belongs to the universal ribosomal protein uS9 family.	0.534