STRINGSTRING
THITE_2123681 THITE_2123681 THITE_2106516 THITE_2106516 THITE_2108321 THITE_2108321 THITE_2109894 THITE_2109894 THITE_2108375 THITE_2108375 THITE_2108409 THITE_2108409 THITE_2106919 THITE_2106919 THITE_2084928 THITE_2084928 THITE_2106972 THITE_2106972 THITE_2110324 THITE_2110324 THITE_2110384 THITE_2110384 THITE_2108888 THITE_2108888 THITE_2108913 THITE_2108913 THITE_2108933 THITE_2108933 THITE_2169677 THITE_2169677 THITE_2040070 THITE_2040070 THITE_2074670 THITE_2074670 THITE_2109066 THITE_2109066 THITE_2107377 THITE_2107377 THITE_2110648 THITE_2110648 THITE_2169523 THITE_2169523 THITE_2109243 THITE_2109243 THITE_2110796 THITE_2110796 THITE_2110805 THITE_2110805 THITE_2107635 THITE_2107635 THITE_2040302 THITE_2040302 THITE_18434 THITE_18434 THITE_2037555 THITE_2037555 THITE_2111002 THITE_2111002 THITE_133987 THITE_133987 THITE_2106178 THITE_2106178 THITE_2109554 THITE_2109554 THITE_2141944 THITE_2141944 THITE_2109598 THITE_2109598 THITE_2106323 THITE_2106323 THITE_133645 THITE_133645 THITE_2169158 THITE_2169158 THITE_2109794 THITE_2109794 THITE_2112191 THITE_2112191 THITE_2170239 THITE_2170239 THITE_2114153 THITE_2114153 THITE_2150588 THITE_2150588 THITE_2115809 THITE_2115809 THITE_2154828 THITE_2154828 THITE_2114323 THITE_2114323 THITE_2112613 THITE_2112613 THITE_2114384 THITE_2114384 THITE_2116070 THITE_2116070 THITE_2112737 THITE_2112737 THITE_2116216 THITE_2116216 THITE_2170062 THITE_2170062 THITE_2112968 THITE_2112968 THITE_38073 THITE_38073 THITE_2113208 THITE_2113208 THITE_2114824 THITE_2114824 THITE_2111426 THITE_2111426 THITE_2113283 THITE_2113283 THITE_2114926 THITE_2114926 THITE_2114951 THITE_2114951 THITE_2046525 THITE_2046525 THITE_2065728 THITE_2065728 THITE_2115047 THITE_2115047 THITE_2113589 THITE_2113589 THITE_2076347 THITE_2076347 THITE_68576 THITE_68576 THITE_2113658 THITE_2113658 THITE_2111949 THITE_2111949 THITE_2064808 THITE_2064808 THITE_2047406 THITE_2047406 THITE_2113850 THITE_2113850 THITE_2113858 THITE_2113858 THITE_2115480 THITE_2115480 THITE_2112030 THITE_2112030 THITE_2115537 THITE_2115537 THITE_2076497 THITE_2076497 THITE_2112147 THITE_2112147 THITE_2112176 THITE_2112176 THITE_2077668 THITE_2077668 THITE_2114060 THITE_2114060 THITE_2115607 THITE_2115607 THITE_125777 THITE_125777 PIM1 PIM1 THITE_2129363 THITE_2129363 THITE_2117766 THITE_2117766 THITE_2117800 THITE_2117800 THITE_2078408 THITE_2078408 THITE_2118035 THITE_2118035 THITE_2145027 THITE_2145027 THITE_2116774 THITE_2116774 THITE_2116842 THITE_2116842 THITE_2117024 THITE_2117024 THITE_2117088 THITE_2117088 THITE_2117090 THITE_2117090 THITE_2117138 THITE_2117138 THITE_2117150 THITE_2117150 THITE_2117176 THITE_2117176 THITE_2117274 THITE_2117274 THITE_2050626 THITE_2050626 THITE_2116310 THITE_2116310 THITE_2117755 THITE_2117755 THITE_2119778 THITE_2119778 THITE_2146429 THITE_2146429 THITE_2118236 THITE_2118236 THITE_113492 THITE_113492 THITE_134760 THITE_134760 THITE_59363 THITE_59363 THITE_2118386 THITE_2118386 THITE_2118392 THITE_2118392 THITE_13076 THITE_13076 MDM10 MDM10 THITE_2120316 THITE_2120316 THITE_2120356 THITE_2120356 THITE_2155455 THITE_2155455 THITE_2118617 THITE_2118617 THITE_2120371 THITE_2120371 THITE_2054227 THITE_2054227 THITE_2118711 THITE_2118711 THITE_2120446 THITE_2120446 THITE_2118754 THITE_2118754 THITE_2118822 THITE_2118822 THITE_155616 THITE_155616 THITE_2118884 THITE_2118884 THITE_2119130 THITE_2119130 THITE_2054065 THITE_2054065 THITE_43951 THITE_43951 CLU1 CLU1 MDM34 MDM34 THITE_2080212 THITE_2080212 THITE_2119527 THITE_2119527 MMM1 MMM1 THITE_121986 THITE_121986 THITE_2119737 THITE_2119737 THITE_2122109 THITE_2122109 THITE_2122249 THITE_2122249 THITE_2120529 THITE_2120529 THITE_2120632 THITE_2120632 THITE_2081050 THITE_2081050 THITE_2120700 THITE_2120700 THITE_23605 THITE_23605 THITE_2120748 THITE_2120748 THITE_2120749 THITE_2120749 THITE_2056950 THITE_2056950 THITE_2122581 THITE_2122581 THITE_2120808 THITE_2120808 THITE_2120874 THITE_2120874 THITE_2120877 THITE_2120877 THITE_2120924 THITE_2120924 THITE_2122885 THITE_2122885 MDM12 MDM12 THITE_2081525 THITE_2081525 THITE_130959 THITE_130959 THITE_2121482 THITE_2121482 THITE_2121637 THITE_2121637 THITE_2121674 THITE_2121674 THITE_108852 THITE_108852 THITE_2097885 THITE_2097885 THITE_2058099 THITE_2058099 THITE_2123004 THITE_2123004 THITE_2156505 THITE_2156505 THITE_2124845 THITE_2124845 THITE_164707 THITE_164707 THITE_49485 THITE_49485 THITE_2123424 THITE_2123424 THITE_2123652 THITE_2123652 THITE_2124121 THITE_2124121
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THITE_2123681Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (85 aa)
THITE_2106516MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (312 aa)
THITE_2108321Uncharacterized protein. (354 aa)
THITE_2109894Uncharacterized protein. (752 aa)
THITE_2108375Uncharacterized protein. (154 aa)
THITE_2108409Uncharacterized protein. (732 aa)
THITE_2106919N-acetyltransferase domain-containing protein. (190 aa)
THITE_2084928Uncharacterized protein. (53 aa)
THITE_2106972Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (941 aa)
THITE_2110324Uncharacterized protein. (304 aa)
THITE_2110384Uncharacterized protein. (829 aa)
THITE_2108888Uncharacterized protein. (631 aa)
THITE_2108913ABC1 domain-containing protein. (516 aa)
THITE_2108933PRELI/MSF1 domain-containing protein. (200 aa)
THITE_2169677Uncharacterized protein. (142 aa)
THITE_2040070Uncharacterized protein. (312 aa)
THITE_2074670Prohibitin. (275 aa)
THITE_2109066Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (124 aa)
THITE_2107377Uncharacterized protein. (223 aa)
THITE_2110648Bac_surface_Ag domain-containing protein. (512 aa)
THITE_2169523Uncharacterized protein. (86 aa)
THITE_2109243Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (390 aa)
THITE_2110796Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (223 aa)
THITE_2110805E3 ubiquitin-protein ligase. (818 aa)
THITE_2107635Uncharacterized protein. (353 aa)
THITE_2040302NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (136 aa)
THITE_18434Uncharacterized protein. (81 aa)
THITE_2037555Uncharacterized protein. (532 aa)
THITE_2111002Uncharacterized protein. (800 aa)
THITE_133987Uncharacterized protein. (552 aa)
THITE_2106178Uncharacterized protein. (751 aa)
THITE_2109554Uncharacterized protein. (148 aa)
THITE_2141944PHB domain-containing protein. (363 aa)
THITE_2109598Uncharacterized protein. (68 aa)
THITE_2106323Uncharacterized protein. (131 aa)
THITE_133645Uncharacterized protein. (316 aa)
THITE_2169158Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (405 aa)
THITE_2109794Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (627 aa)
THITE_2112191HMG box domain-containing protein. (308 aa)
THITE_2170239Uncharacterized protein. (282 aa)
THITE_2114153DNL-type domain-containing protein. (244 aa)
THITE_2150588Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (153 aa)
THITE_2115809Uncharacterized protein. (571 aa)
THITE_2154828Uncharacterized protein. (796 aa)
THITE_2114323Sensitive to high expression protein 9, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. (487 aa)
THITE_2112613Uncharacterized protein. (231 aa)
THITE_2114384Uncharacterized protein. (299 aa)
THITE_2116070Uncharacterized protein; Belongs to the GroES chaperonin family. (104 aa)
THITE_2112737Uncharacterized protein. (116 aa)
THITE_2116216CHCH domain-containing protein. (300 aa)
THITE_2170062Uncharacterized protein. (115 aa)
THITE_2112968Uncharacterized protein. (355 aa)
THITE_38073Uncharacterized protein. (383 aa)
THITE_2113208ATG11 domain-containing protein. (1293 aa)
THITE_2114824Uncharacterized protein. (431 aa)
THITE_2111426Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (381 aa)
THITE_2113283Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
THITE_2114926Uncharacterized protein. (181 aa)
THITE_2114951WD_REPEATS_REGION domain-containing protein. (658 aa)
THITE_2046525Uncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (128 aa)
THITE_2065728Uncharacterized protein. (105 aa)
THITE_2115047AAA domain-containing protein; Belongs to the AAA ATPase family. (420 aa)
THITE_2113589COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (166 aa)
THITE_2076347SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (313 aa)
THITE_68576Uncharacterized protein. (160 aa)
THITE_2113658Uncharacterized protein. (131 aa)
THITE_2111949Uncharacterized protein. (133 aa)
THITE_2064808Uncharacterized protein. (330 aa)
THITE_2047406DNA_MISMATCH_REPAIR_2 domain-containing protein. (1057 aa)
THITE_2113850DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1158 aa)
THITE_2113858MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (285 aa)
THITE_2115480Uncharacterized protein. (725 aa)
THITE_2112030Uncharacterized protein. (465 aa)
THITE_2115537Uncharacterized protein. (130 aa)
THITE_2076497Uncharacterized protein. (292 aa)
THITE_2112147L51_S25_CI-B8 domain-containing protein. (92 aa)
THITE_2112176Uncharacterized protein. (131 aa)
THITE_2077668Uncharacterized protein; Belongs to the complex I LYR family. (77 aa)
THITE_2114060Uncharacterized protein. (76 aa)
THITE_2115607Uncharacterized protein. (669 aa)
THITE_125777Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (477 aa)
PIM1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1095 aa)
THITE_2129363Altered inheritance of mitochondria protein 24, mitochondrial. (393 aa)
THITE_2117766DNA ligase. (881 aa)
THITE_2117800Uncharacterized protein. (52 aa)
THITE_2078408Uncharacterized protein. (121 aa)
THITE_2118035Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3213 aa)
THITE_2145027Sulfhydryl oxidase. (186 aa)
THITE_2116774Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (896 aa)
THITE_2116842HIG1 domain-containing protein. (226 aa)
THITE_2117024Uncharacterized protein. (77 aa)
THITE_2117088Uncharacterized protein. (608 aa)
THITE_2117090Uncharacterized protein. (176 aa)
THITE_2117138Uncharacterized protein. (266 aa)
THITE_2117150Uncharacterized protein. (124 aa)
THITE_2117176Uncharacterized protein. (198 aa)
THITE_2117274Uncharacterized protein. (602 aa)
THITE_2050626DUF2263 domain-containing protein. (393 aa)
THITE_2116310Uncharacterized protein. (223 aa)
THITE_2117755Cytochrome c oxidase assembly protein COX20, mitochondrial; Involved in the assembly of the cytochrome c oxidase complex. Belongs to the COX20 family. (203 aa)
THITE_2119778Uncharacterized protein. (329 aa)
THITE_2146429CHY-type domain-containing protein. (131 aa)
THITE_2118236Uncharacterized protein. (499 aa)
THITE_113492Uncharacterized protein. (321 aa)
THITE_134760Uncharacterized protein. (176 aa)
THITE_59363Uncharacterized protein. (166 aa)
THITE_2118386PPM-type phosphatase domain-containing protein. (585 aa)
THITE_2118392Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (940 aa)
THITE_13076Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (447 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (450 aa)
THITE_2120316Uncharacterized protein. (369 aa)
THITE_2120356Uncharacterized protein; Belongs to the AAA ATPase family. (671 aa)
THITE_2155455Tafazzin family protein; Belongs to the taffazin family. (404 aa)
THITE_2118617Uncharacterized protein. (100 aa)
THITE_2120371Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (121 aa)
THITE_2054227NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (230 aa)
THITE_2118711POLAc domain-containing protein. (1198 aa)
THITE_2120446Uncharacterized protein. (152 aa)
THITE_2118754PUM-HD domain-containing protein. (916 aa)
THITE_2118822Uncharacterized protein. (184 aa)
THITE_155616MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (86 aa)
THITE_2118884Uncharacterized protein. (347 aa)
THITE_2119130Uncharacterized protein; Belongs to the peptidase M16 family. (603 aa)
THITE_2054065Uncharacterized protein. (97 aa)
THITE_43951Uncharacterized protein. (517 aa)
CLU1Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. (1286 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (543 aa)
THITE_2080212Uncharacterized protein. (237 aa)
THITE_2119527zf-Mss51 domain-containing protein. (495 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (497 aa)
THITE_121986zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (88 aa)
THITE_2119737J domain-containing protein. (107 aa)
THITE_2122109Uncharacterized protein; Belongs to the peptidase M16 family. (475 aa)
THITE_2122249MPN domain-containing protein. (337 aa)
THITE_2120529Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (438 aa)
THITE_2120632AAA domain-containing protein. (719 aa)
THITE_2081050Uncharacterized protein; Belongs to the BI1 family. (346 aa)
THITE_2120700MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (697 aa)
THITE_23605Tom37 domain-containing protein. (401 aa)
THITE_2120748Vps5 domain-containing protein. (365 aa)
THITE_2120749Letm1 RBD domain-containing protein. (560 aa)
THITE_2056950Uncharacterized protein. (481 aa)
THITE_2122581Uncharacterized protein. (255 aa)
THITE_2120808zf-Tim10_DDP domain-containing protein. (92 aa)
THITE_2120874Tim44 domain-containing protein. (542 aa)
THITE_2120877Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa)
THITE_2120924TYR_PHOSPHATASE_2 domain-containing protein. (660 aa)
THITE_2122885Uncharacterized membrane protein. (190 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (486 aa)
THITE_2081525Uncharacterized protein. (203 aa)
THITE_130959HIG1 domain-containing protein. (237 aa)
THITE_2121482Uncharacterized protein; Belongs to the ClpA/ClpB family. (798 aa)
THITE_2121637Prohibitin. (310 aa)
THITE_2121674Uncharacterized protein. (337 aa)
THITE_108852COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (80 aa)
THITE_2097885GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (250 aa)
THITE_2058099Uncharacterized protein. (139 aa)
THITE_2123004RRM domain-containing protein. (862 aa)
THITE_2156505Uncharacterized protein. (294 aa)
THITE_2124845Uncharacterized protein. (196 aa)
THITE_164707Methyltransf_11 domain-containing protein. (351 aa)
THITE_49485SAP domain-containing protein. (378 aa)
THITE_2123424AAA domain-containing protein. (863 aa)
THITE_2123652Uncharacterized protein. (228 aa)
THITE_2124121Uncharacterized protein. (584 aa)
Your Current Organism:
Thermothielavioides terrestris
NCBI taxonomy Id: 578455
Other names: T. terrestris NRRL 8126, Thermothielavioides terrestris NRRL 8126
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