42 items (Thermothielavioides terrestris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THITE_2118883	Uncharacterized protein; Belongs to the ClpA/ClpB family. (923 aa)
	THITE_2171644	AAA domain-containing protein. (735 aa)
	THITE_2124121	Uncharacterized protein. (584 aa)
	THITE_2123739	Uncharacterized protein. (827 aa)
	THITE_2123424	AAA domain-containing protein. (863 aa)
	THITE_2124869	Uncharacterized protein. (594 aa)
	THITE_2123254	Uncharacterized protein. (867 aa)
	THITE_2124823	AAA domain-containing protein. (389 aa)
	THITE_2122938	AAA domain-containing protein. (766 aa)
	THITE_2122931	AAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
	THITE_2124524	Replication factor C subunit 1. (1058 aa)
	THITE_2121913	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	THITE_2121518	AAA domain-containing protein. (1434 aa)
	THITE_2121482	Uncharacterized protein; Belongs to the ClpA/ClpB family. (798 aa)
	THITE_2122886	AAA domain-containing protein. (470 aa)
	THITE_2120877	Uncharacterized protein; Belongs to the AAA ATPase family. (462 aa)
	THITE_2122445	AAA domain-containing protein. (1020 aa)
	THITE_2120632	AAA domain-containing protein. (719 aa)
	THITE_2119267	Uncharacterized protein; Belongs to the AAA ATPase family. (822 aa)
	THITE_2120356	Uncharacterized protein; Belongs to the AAA ATPase family. (671 aa)
	THITE_2120339	AAA domain-containing protein. (1278 aa)
	THITE_2119849	Uncharacterized protein. (1788 aa)
	THITE_2117667	Uncharacterized protein; Belongs to the AAA ATPase family. (438 aa)
	THITE_2117266	AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
	THITE_2116768	AAA domain-containing protein. (822 aa)
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1095 aa)
	THITE_2114020	Uncharacterized protein. (1266 aa)
	THITE_2115523	Uncharacterized protein. (782 aa)
	THITE_2115270	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (942 aa)
	THITE_2115047	AAA domain-containing protein; Belongs to the AAA ATPase family. (420 aa)
	THITE_2114872	AAA domain-containing protein; Belongs to the AAA ATPase family. (460 aa)
	THITE_32934	AAA domain-containing protein; Belongs to the AAA ATPase family. (326 aa)
	THITE_2116143	AAA domain-containing protein. (985 aa)
	THITE_2112643	AAA domain-containing protein. (703 aa)
	THITE_2112577	AAA domain-containing protein; Belongs to the AAA ATPase family. (391 aa)
	THITE_2112355	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (781 aa)
	THITE_2112208	AAA domain-containing protein. (383 aa)
	THITE_2108012	AAA domain-containing protein; Belongs to the AAA ATPase family. (459 aa)
	THITE_2107345	AAA domain-containing protein. (908 aa)
	THITE_2106865	AAA domain-containing protein. (358 aa)
	THITE_2108409	Uncharacterized protein. (732 aa)
	THITE_2109894	Uncharacterized protein. (752 aa)

Your Current Organism:

Thermothielavioides terrestris

NCBI taxonomy Id: 578455
Other names: T. terrestris NRRL 8126, Thermothielavioides terrestris NRRL 8126

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PIM1	THITE_2107345	G2R5A9	G2QTR2	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	AAA domain-containing protein.	0.625
PIM1	THITE_2108409	G2R5A9	G2QR67	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein.	0.406
PIM1	THITE_2109894	G2R5A9	G2QQU7	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein.	0.406
PIM1	THITE_2118883	G2R5A9	G2RB01	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein; Belongs to the ClpA/ClpB family.	0.630
PIM1	THITE_2120356	G2R5A9	G2RA82	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.406
PIM1	THITE_2120877	G2R5A9	G2RDV4	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.406
PIM1	THITE_2121482	G2R5A9	G2REY9	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein; Belongs to the ClpA/ClpB family.	0.625
PIM1	THITE_2123424	G2R5A9	G2RHD0	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	AAA domain-containing protein.	0.623
PIM1	THITE_2124121	G2R5A9	G2RIB3	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	Uncharacterized protein.	0.674
THITE_2106865	THITE_2112208	G2QRW7	G2QY36	AAA domain-containing protein.	AAA domain-containing protein.	0.999
THITE_2106865	THITE_2120339	G2QRW7	G2RA70	AAA domain-containing protein.	AAA domain-containing protein.	0.970
THITE_2106865	THITE_2122445	G2QRW7	G2RD97	AAA domain-containing protein.	AAA domain-containing protein.	0.978
THITE_2106865	THITE_2124524	G2QRW7	G2RFX8	AAA domain-containing protein.	Replication factor C subunit 1.	0.999
THITE_2106865	THITE_2124823	G2QRW7	G2RGU2	AAA domain-containing protein.	AAA domain-containing protein.	0.999
THITE_2107345	PIM1	G2QTR2	G2R5A9	AAA domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.625
THITE_2107345	THITE_2115270	G2QTR2	G2R3W7	AAA domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.623
THITE_2107345	THITE_2123424	G2QTR2	G2RHD0	AAA domain-containing protein.	AAA domain-containing protein.	0.404
THITE_2107345	THITE_2124121	G2QTR2	G2RIB3	AAA domain-containing protein.	Uncharacterized protein.	0.694
THITE_2108012	THITE_2112355	G2QWV6	G2QYL7	AAA domain-containing protein; Belongs to the AAA ATPase family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.619
THITE_2108012	THITE_2112577	G2QWV6	G2QZH8	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999