STRINGSTRING
A0A194SCD6 A0A194SCD6 A0A194SDE3 A0A194SDE3 A0A194SDE4 A0A194SDE4 A0A194SDL6 A0A194SDL6 A0A194SDM2 A0A194SDM2 A0A194SDS3 A0A194SDS3 CIA1 CIA1 A0A194SFS5 A0A194SFS5 A0A194SG87 A0A194SG87 A0A0P9F943 A0A0P9F943 A0A194S943 A0A194S943 A0A194S994 A0A194S994 A0A194S9C0 A0A194S9C0 A0A194S9T5 A0A194S9T5 A0A194S9U6 A0A194S9U6 A0A194S9X0 A0A194S9X0 A0A194SAC0 A0A194SAC0 MET3 MET3 A0A194SAZ0 A0A194SAZ0 A0A194SBD8 A0A194SBD8 A0A194SBI2 A0A194SBI2 A0A0N8PZ90 A0A0N8PZ90 A0A0N8PZB2 A0A0N8PZB2 TAH18 TAH18 A0A0N8PZM5 A0A0N8PZM5 A0A0N8PZW6 A0A0N8PZW6 A0A0N8PZY5 A0A0N8PZY5 A0A0N8Q025 A0A0N8Q025 A0A0P9EEE2 A0A0P9EEE2 A0A0P9EEH6 A0A0P9EEH6 A0A0P9EEZ0 A0A0P9EEZ0 A0A0P9EG48 A0A0P9EG48 A0A0P9EG66 A0A0P9EG66 A0A0P9EH56 A0A0P9EH56 A0A0P9EHS0 A0A0P9EHS0 A0A0P9EIB0 A0A0P9EIB0 A0A0P9EIF0 A0A0P9EIF0 A0A0P9EIR7 A0A0P9EIR7 A0A0P9EL42 A0A0P9EL42 A0A0P9ERA8 A0A0P9ERA8 A0A0P9ESS9 A0A0P9ESS9 A0A0P9ET97 A0A0P9ET97 A0A0P9ETV2 A0A0P9ETV2 A0A0P9ETW1 A0A0P9ETW1 A0A0P9EUT3 A0A0P9EUT3 A0A0P9EVD6 A0A0P9EVD6 A0A0P9EVK5 A0A0P9EVK5 A0A0P9EX18 A0A0P9EX18 A0A0P9EX58 A0A0P9EX58 A0A0P9EYP4 A0A0P9EYP4 A0A0P9EZ45 A0A0P9EZ45 A0A0P9EZX5 A0A0P9EZX5 A0A0P9F117 A0A0P9F117 A0A0P9F1V1 A0A0P9F1V1 A0A0P9F280 A0A0P9F280 A0A0P9F2I2 A0A0P9F2I2 A0A0P9F755 A0A0P9F755 A0A0P9F7Q8 A0A0P9F7Q8 A0A0P9F816 A0A0P9F816 A0A194SBP5 A0A194SBP5 A0A194SBQ6 A0A194SBQ6 A0A194SBR1 A0A194SBR1 A0A194SBS2 A0A194SBS2 A0A194SBX6 A0A194SBX6 DRE2 DRE2 A0A0P9F9W3 A0A0P9F9W3 A0A0P9FA16 A0A0P9FA16 A0A0P9FB97 A0A0P9FB97 A0A0P9GG50 A0A0P9GG50 A0A0P9GIJ8 A0A0P9GIJ8 A0A0P9GJI7 A0A0P9GJI7 A0A0P9GJY5 A0A0P9GJY5 A0A0P9GJY9 A0A0P9GJY9 A0A0P9GKK9 A0A0P9GKK9 A0A0P9GWI7 A0A0P9GWI7 A0A0P9GZ54 A0A0P9GZ54 A0A0P9GZ77 A0A0P9GZ77 A0A0P9GZZ1 A0A0P9GZZ1 A0A0P9H0M2 A0A0P9H0M2 A0A0P9H0Q6 A0A0P9H0Q6 A0A0P9H1G9 A0A0P9H1G9 A0A0P9IQR2 A0A0P9IQR2 A0A0P9ISB2 A0A0P9ISB2 A0A0P9ITI8 A0A0P9ITI8 A0A0P9ITY8 A0A0P9ITY8 A0A0P9IU11 A0A0P9IU11 A0A0P9IVE6 A0A0P9IVE6 A0A194S0V7 A0A194S0V7 A0A194S1A4 A0A194S1A4 A0A194S1B6 A0A194S1B6 A0A194S1D0 A0A194S1D0 A0A194S1L6 A0A194S1L6 A0A194S1M3 A0A194S1M3 A0A194S1W6 A0A194S1W6 A0A194S230 A0A194S230 A0A194S2B3 A0A194S2B3 A0A194S2C6 A0A194S2C6 A0A194S2T8 A0A194S2T8 ADI1 ADI1 A0A194S340 A0A194S340 NBP35 NBP35 A0A194S3K4 A0A194S3K4 A0A194S3P0 A0A194S3P0 A0A194S3U8 A0A194S3U8 A0A194S411 A0A194S411 A0A194S432 A0A194S432 A0A194S446 A0A194S446 A0A194S451 A0A194S451 A0A194S480 A0A194S480 A0A194S4B5 A0A194S4B5 A0A194S4E2 A0A194S4E2 A0A194S4G3 A0A194S4G3 A0A194S4H0 A0A194S4H0 A0A194S4J2 A0A194S4J2 A0A194S4L4 A0A194S4L4 A0A194S4P2 A0A194S4P2 A0A194S4S3 A0A194S4S3 A0A194S4S7 A0A194S4S7 A0A194S5A1 A0A194S5A1 A0A194S5H6 A0A194S5H6 A0A194S5N9 A0A194S5N9 A0A194S5T2 A0A194S5T2 A0A194S5X8 A0A194S5X8 A0A194S645 A0A194S645 A0A194S663 A0A194S663 A0A194S6J2 A0A194S6J2 A0A194S6M1 A0A194S6M1 A0A194S6S9 A0A194S6S9 A0A194S6U6 A0A194S6U6 A0A194S717 A0A194S717 A0A194S7J5 A0A194S7J5 A0A194S7N5 A0A194S7N5 A0A194S8G3 A0A194S8G3 A0A194S8L4 A0A194S8L4 A0A194S8Q4 A0A194S8Q4 A0A194S905 A0A194S905
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A194SCD6Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (286 aa)
A0A194SDE3Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (865 aa)
A0A194SDE4Uncharacterized protein. (410 aa)
A0A194SDL6Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (491 aa)
A0A194SDM2Uncharacterized protein. (426 aa)
A0A194SDS3Homoserine dehydrogenase. (407 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (433 aa)
A0A194SFS5Uncharacterized protein. (437 aa)
A0A194SG87Uncharacterized protein; Belongs to the GST superfamily. (257 aa)
A0A0P9F943Uncharacterized protein. (443 aa)
A0A194S943Uncharacterized protein. (335 aa)
A0A194S994Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (625 aa)
A0A194S9C0Uncharacterized protein; Belongs to the GST superfamily. (235 aa)
A0A194S9T5PALP domain-containing protein. (382 aa)
A0A194S9U6PAPS_reduct domain-containing protein. (310 aa)
A0A194S9X0S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (368 aa)
A0A194SAC0Uncharacterized protein. (339 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (596 aa)
A0A194SAZ0Probable acetate kinase. (321 aa)
A0A194SBD8Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (422 aa)
A0A194SBI2Uncharacterized protein. (171 aa)
A0A0N8PZ90Uncharacterized protein. (101 aa)
A0A0N8PZB2Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (170 aa)
TAH18NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (605 aa)
A0A0N8PZM5Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa)
A0A0N8PZW6Rhodanese domain-containing protein. (170 aa)
A0A0N8PZY54HBT domain-containing protein. (166 aa)
A0A0N8Q025Adenosylhomocysteinase. (430 aa)
A0A0P9EEE2Uncharacterized protein. (839 aa)
A0A0P9EEH6Fe-S_biosyn domain-containing protein. (191 aa)
A0A0P9EEZ0Uncharacterized protein. (145 aa)
A0A0P9EG48Uncharacterized protein. (85 aa)
A0A0P9EG66Uncharacterized protein. (282 aa)
A0A0P9EH56Hydantoinase_B domain-containing protein. (584 aa)
A0A0P9EHS0Uncharacterized protein. (324 aa)
A0A0P9EIB0Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (396 aa)
A0A0P9EIF0NMT1 domain-containing protein. (356 aa)
A0A0P9EIR7Uncharacterized protein. (172 aa)
A0A0P9EL42Uncharacterized protein. (770 aa)
A0A0P9ERA8Uncharacterized protein. (352 aa)
A0A0P9ESS9Uncharacterized protein. (416 aa)
A0A0P9ET97Glutathione synthetase. (527 aa)
A0A0P9ETV2Uncharacterized protein. (165 aa)
A0A0P9ETW1Uncharacterized protein. (751 aa)
A0A0P9EUT3Uncharacterized protein. (221 aa)
A0A0P9EVD6SOR_SNZ domain-containing protein; Belongs to the PdxS/SNZ family. (315 aa)
A0A0P9EVK5AMP-binding domain-containing protein. (998 aa)
A0A0P9EX18Meth_synt_2 domain-containing protein. (396 aa)
A0A0P9EX58Uncharacterized protein. (151 aa)
A0A0P9EYP4ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1153 aa)
A0A0P9EZ45Uncharacterized protein. (510 aa)
A0A0P9EZX5Uncharacterized protein. (343 aa)
A0A0P9F117Aminotran_5 domain-containing protein. (466 aa)
A0A0P9F1V1Nfu_N domain-containing protein. (220 aa)
A0A0P9F280Uncharacterized protein. (536 aa)
A0A0P9F2I2Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (754 aa)
A0A0P9F755Uncharacterized protein; Belongs to the GST superfamily. (246 aa)
A0A0P9F7Q8Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (419 aa)
A0A0P9F816Uncharacterized protein. (548 aa)
A0A194SBP5Uncharacterized protein. (768 aa)
A0A194SBQ6Uncharacterized protein. (502 aa)
A0A194SBR1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (329 aa)
A0A194SBS2Uncharacterized protein. (108 aa)
A0A194SBX6Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (423 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (334 aa)
A0A0P9F9W3Uncharacterized protein. (602 aa)
A0A0P9FA16Uncharacterized protein. (253 aa)
A0A0P9FB97Pyr_redox_2 domain-containing protein. (444 aa)
A0A0P9GG50PALP domain-containing protein. (387 aa)
A0A0P9GIJ8Uncharacterized protein; Belongs to the GST superfamily. (232 aa)
A0A0P9GJI7GGACT domain-containing protein. (166 aa)
A0A0P9GJY5Uncharacterized protein. (621 aa)
A0A0P9GJY9TP_methylase domain-containing protein. (373 aa)
A0A0P9GKK9Meth_synt_2 domain-containing protein. (402 aa)
A0A0P9GWI7Uncharacterized protein. (51 aa)
A0A0P9GZ54Uncharacterized protein. (193 aa)
A0A0P9GZ77Glutamine amidotransferase type-2 domain-containing protein. (431 aa)
A0A0P9GZZ1Uncharacterized protein. (940 aa)
A0A0P9H0M2Uncharacterized protein; Belongs to the GST superfamily. (174 aa)
A0A0P9H0Q6Uncharacterized protein. (661 aa)
A0A0P9H1G9Uncharacterized protein. (817 aa)
A0A0P9IQR2Uncharacterized protein. (429 aa)
A0A0P9ISB2Nudix hydrolase domain-containing protein. (281 aa)
A0A0P9ITI8Aminotran_5 domain-containing protein. (423 aa)
A0A0P9ITY8Uncharacterized protein. (386 aa)
A0A0P9IU11Lactamase_B domain-containing protein. (375 aa)
A0A0P9IVE6Acetyl-coenzyme A synthetase. (660 aa)
A0A194S0V7Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (529 aa)
A0A194S1A4TauD domain-containing protein. (379 aa)
A0A194S1B6Uncharacterized protein; Belongs to the GST superfamily. (271 aa)
A0A194S1D0J domain-containing protein. (721 aa)
A0A194S1L6Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (178 aa)
A0A194S1M3Flavodoxin-like domain-containing protein. (905 aa)
A0A194S1W6TMP-TENI domain-containing protein. (543 aa)
A0A194S230Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (209 aa)
A0A194S2B3Uncharacterized protein. (629 aa)
A0A194S2C6Semialdhyde_dh domain-containing protein. (363 aa)
A0A194S2T8Uncharacterized protein. (394 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (173 aa)
A0A194S340FAD-binding FR-type domain-containing protein. (1036 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (353 aa)
A0A194S3K4Uncharacterized protein. (310 aa)
A0A194S3P0Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (360 aa)
A0A194S3U83-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (482 aa)
A0A194S411Uncharacterized protein. (741 aa)
A0A194S432Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (604 aa)
A0A194S446Uncharacterized protein. (524 aa)
A0A194S451Lipoyl-binding domain-containing protein. (458 aa)
A0A194S480Uncharacterized protein. (1109 aa)
A0A194S4B5J domain-containing protein. (272 aa)
A0A194S4E2Homoserine dehydrogenase. (397 aa)
A0A194S4G3Uncharacterized protein. (2238 aa)
A0A194S4H0GST N-terminal domain-containing protein. (220 aa)
A0A194S4J2GST C-terminal domain-containing protein. (332 aa)
A0A194S4L4UDP-glucose 6-dehydrogenase. (475 aa)
A0A194S4P2Uncharacterized protein. (363 aa)
A0A194S4S3GHMP_kinases_N domain-containing protein. (883 aa)
A0A194S4S7RmlD_sub_bind domain-containing protein. (299 aa)
A0A194S5A1FeS_assembly_P domain-containing protein. (197 aa)
A0A194S5H6M20_dimer domain-containing protein. (492 aa)
A0A194S5N9TauD domain-containing protein. (364 aa)
A0A194S5T2LigB domain-containing protein. (290 aa)
A0A194S5X8Uncharacterized protein. (247 aa)
A0A194S645Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (489 aa)
A0A194S6632Fe-2S ferredoxin-type domain-containing protein. (190 aa)
A0A194S6J2Uncharacterized protein; Belongs to the complex I LYR family. (182 aa)
A0A194S6M1Zn(2)-C6 fungal-type domain-containing protein. (864 aa)
A0A194S6S9AMP-binding domain-containing protein. (682 aa)
A0A194S6U6Uncharacterized protein; Belongs to the GST superfamily. (235 aa)
A0A194S717Uncharacterized protein. (576 aa)
A0A194S7J5S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (384 aa)
A0A194S7N5Uncharacterized protein. (559 aa)
A0A194S8G3Fe-S_biosyn domain-containing protein. (97 aa)
A0A194S8L4GST N-terminal domain-containing protein. (264 aa)
A0A194S8Q4Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (336 aa)
A0A194S905Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (205 aa)
Your Current Organism:
Rhodotorula graminis
NCBI taxonomy Id: 578459
Other names: R. graminis WP1, Rhodotorula graminis WP1
Server load: low (18%) [HD]