(158 nodes) Reproduction network (Dictyostelium purpureum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F0ZB69_DICPU	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (441 aa)
	F0Z6I2_DICPU	Uncharacterized protein. (810 aa)
	F0Z6K6_DICPU	EGF-like domain-containing protein. (1024 aa)
	F0Z6T6_DICPU	Uncharacterized protein. (289 aa)
	F0Z7C1_DICPU	AAA domain-containing protein; Belongs to the AAA ATPase family. (349 aa)
	F0Z7E7_DICPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1729 aa)
	F0Z7F4_DICPU	EGF-like domain-containing protein. (1790 aa)
	F0Z810_DICPU	Uncharacterized protein. (1342 aa)
	racL	Uncharacterized protein racL. (196 aa)
	racJ	Uncharacterized protein racJ. (206 aa)
	F0Z8A7_DICPU	Protein serine/threonine kinase; Belongs to the protein kinase superfamily. (338 aa)
	F0Z8T7_DICPU	Cnd1 domain-containing protein. (1754 aa)
	F0Z936_DICPU	Uncharacterized protein. (821 aa)
	F0Z988_DICPU	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1455 aa)
	F0Z9G3_DICPU	Uncharacterized protein. (308 aa)
	F0Z9H2_DICPU	TCTP domain-containing protein; Belongs to the TCTP family. (171 aa)
	F0ZA37_DICPU	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (409 aa)
	F0ZAK4_DICPU	FHA domain-containing protein. (574 aa)
	F0ZAQ0_DICPU	Peptidase S53 domain-containing protein. (672 aa)
	racG	Uncharacterized protein racG. (194 aa)
	F0ZMB0_DICPU	Uncharacterized protein. (445 aa)
	F0ZME5_DICPU	Uncharacterized protein. (450 aa)
	F0ZMV1_DICPU	Inositol 5-phosphatase 4. (775 aa)
	F0ZMW3_DICPU	EGF-like domain-containing protein. (1023 aa)
	F0ZMY9_DICPU	Uncharacterized protein. (829 aa)
	racE	Uncharacterized protein racE. (220 aa)
	F0ZN98_DICPU	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (489 aa)
	F0ZNB2_DICPU	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1162 aa)
	F0ZNF2_DICPU	ERCC4 domain-containing protein. (902 aa)
	F0ZNL5_DICPU	Uncharacterized protein. (1201 aa)
	F0ZP57_DICPU	PITH domain-containing protein. (201 aa)
	F0ZP61_DICPU	Actin bundling protein. (611 aa)
	F0ZPT9_DICPU	CBS domain-containing protein. (196 aa)
	F0ZPV1_DICPU	EGF-like domain-containing protein. (726 aa)
	F0ZPX2_DICPU	Uncharacterized protein. (639 aa)
	F0ZPX3_DICPU	Uncharacterized protein. (747 aa)
	F0ZQ22_DICPU	Cortexillin I. (431 aa)
	F0ZQH1_DICPU	Uncharacterized protein. (1312 aa)
	F0ZQW1_DICPU	Protein kinase domain-containing protein. (831 aa)
	F0ZQX2_DICPU	Uncharacterized protein. (731 aa)
	F0ZQY5_DICPU	Checkpoint protein; Belongs to the HUS1 family. (272 aa)
	F0ZQY7_DICPU	Phosducin domain-containing protein. (240 aa)
	F0ZQY9_DICPU	Peptidylprolyl isomerase. (195 aa)
	F0ZR37_DICPU	Uncharacterized protein. (349 aa)
	F0ZR44_DICPU	Uncharacterized protein. (603 aa)
	F0ZR50_DICPU	DNA_MISMATCH_REPAIR_2 domain-containing protein. (846 aa)
	F0ZR62_DICPU	Uncharacterized protein. (1529 aa)
	F0ZRF4_DICPU	Uncharacterized protein. (848 aa)
	F0ZRK6_DICPU	NAD_binding_4 domain-containing protein. (1659 aa)
	F0ZRP1_DICPU	Uncharacterized protein. (483 aa)
	F0ZRX0_DICPU	Uncharacterized protein. (470 aa)
	F0ZRX1_DICPU	Uncharacterized protein. (1559 aa)
	F0ZSA5_DICPU	Peptidase C50 domain-containing protein. (2228 aa)
	F0ZSG8_DICPU	PA14 domain-containing protein. (720 aa)
	F0ZSG9_DICPU	PA14 domain-containing protein. (717 aa)
	F0ZSQ6_DICPU	Uncharacterized protein. (442 aa)
	F0ZT69_DICPU	RECA_2 domain-containing protein. (275 aa)
	F0ZTL9_DICPU	Uncharacterized protein. (787 aa)
	F0ZTT0_DICPU	Cell division cycle protein 48; Belongs to the AAA ATPase family. (792 aa)
	F0ZUE3_DICPU	BUB1 N-terminal domain-containing protein. (1213 aa)
	F0ZUL4_DICPU	Uncharacterized protein. (210 aa)
	F0ZUR5_DICPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1132 aa)
	rasS	Uncharacterized protein rasS. (194 aa)
	F0ZVV5_DICPU	Uncharacterized protein. (1699 aa)
	F0ZVW1_DICPU	EGF-like domain-containing protein. (1499 aa)
	F0ZW03_DICPU	HAP2-GCS1 domain-containing protein. (651 aa)
	F0ZW19_DICPU	Uncharacterized protein. (298 aa)
	F0ZW84_DICPU	Uncharacterized protein. (1257 aa)
	F0ZWC9_DICPU	Uncharacterized protein. (1335 aa)
	rasG	Uncharacterized protein rasG. (189 aa)
	F0ZWG6_DICPU	Ammonium transporter. (450 aa)
	F0ZWR1_DICPU	Uncharacterized protein. (1263 aa)
	F0ZX52_DICPU	Citrate synthase; Belongs to the citrate synthase family. (491 aa)
	F0ZX72_DICPU	Uncharacterized protein. (406 aa)
	F0ZXH4_DICPU	Mov34/MPN/PAD-1 family protein. (332 aa)
	F0ZY59_DICPU	Profilin; Belongs to the profilin family. (127 aa)
	F0ZY60_DICPU	Profilin; Belongs to the profilin family. (128 aa)
	F0ZYI7_DICPU	Uncharacterized protein. (928 aa)
	F0ZYS5_DICPU	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (639 aa)
	F0ZZJ5_DICPU	TMF_TATA_bd domain-containing protein. (965 aa)
	F0ZZM8_DICPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1485 aa)
	F0ZZQ4_DICPU	Uncharacterized protein. (1340 aa)
	F0ZZZ2_DICPU	Phos_pyr_kin domain-containing protein. (304 aa)
	F0ZZZ5_DICPU	Uncharacterized protein. (715 aa)
	F1A0G6_DICPU	Uncharacterized protein. (978 aa)
	F1A206_DICPU	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (588 aa)
	F1A208_DICPU	Act-Frag_cataly domain-containing protein. (294 aa)
	F1A2C9_DICPU	Helicase ATP-binding domain-containing protein. (617 aa)
	F1A2H6_DICPU	Protein disulfide-isomerase. (456 aa)
	F1A2T1_DICPU	WD_REPEATS_REGION domain-containing protein. (596 aa)
	F1A2Y8_DICPU	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (499 aa)
	F1A313_DICPU	Uncharacterized protein. (203 aa)
	F1A347_DICPU	Ras GTPase-activating protein. (787 aa)
	F1A352_DICPU	Uncharacterized protein. (1333 aa)
	F1A3D0_DICPU	SWIM-type domain-containing protein. (948 aa)
	F1A3E9_DICPU	Uncharacterized protein. (1435 aa)
	rasC	Uncharacterized protein rasC. (189 aa)
	F1A423_DICPU	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (585 aa)
	F1A4A3_DICPU	EGF-like domain-containing protein. (635 aa)
	F1A4D5_DICPU	DUF1767 domain-containing protein. (550 aa)
	F1A4H2_DICPU	Uncharacterized protein. (228 aa)
	F1A4J5_DICPU	Uncharacterized protein. (1229 aa)
	F0ZB73_DICPU	Uncharacterized protein. (2666 aa)
	F0ZB94_DICPU	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1260 aa)
	F0ZBM0_DICPU	Spindle pole body component. (826 aa)
	F0ZBM3_DICPU	DNA_MISMATCH_REPAIR_2 domain-containing protein. (1045 aa)
	F0ZBX6_DICPU	SAP domain-containing protein. (694 aa)
	F0ZC40_DICPU	Uncharacterized protein. (1194 aa)
	F0ZC64_DICPU	RPN13_C domain-containing protein. (305 aa)
	F0ZC84_DICPU	PA14 domain-containing protein. (705 aa)
	F0ZC93_DICPU	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (457 aa)
	F0ZCE1_DICPU	Uncharacterized protein. (931 aa)
	F0ZCV2_DICPU	EGF-like domain-containing protein. (486 aa)
	F0ZCW6_DICPU	Uncharacterized protein. (159 aa)
	F0ZCX8_DICPU	Allantoicase. (343 aa)
	F0ZD04_DICPU	Uncharacterized protein. (1338 aa)
	F0ZD73_DICPU	P34-cdc2 protein; Belongs to the protein kinase superfamily. (352 aa)
	F0ZDB7_DICPU	Uncharacterized protein. (1186 aa)
	F0ZDP6_DICPU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (355 aa)
	F0ZDU0_DICPU	Nucleoside diphosphate kinase. (152 aa)
	F0ZDY8_DICPU	Uncharacterized protein. (1074 aa)
	F0ZDY9_DICPU	Uncharacterized protein. (1341 aa)
	F0ZDZ8_DICPU	PA14 domain-containing protein. (729 aa)
	F0ZDZ9_DICPU	PA14 domain-containing protein. (729 aa)
	F0ZE00_DICPU	PA14 domain-containing protein. (722 aa)
	F0ZE02_DICPU	Uncharacterized protein. (171 aa)
	F0ZE64_DICPU	Uncharacterized protein. (517 aa)
	F0ZEE6_DICPU	RING-type domain-containing protein. (392 aa)
	F0ZEX8_DICPU	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (195 aa)
	F0ZEX9_DICPU	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (171 aa)
	F0ZF26_DICPU	Uncharacterized protein. (404 aa)
	F0ZFJ5_DICPU	EGF-like domain-containing protein. (903 aa)
	F0ZFL7_DICPU	Chaperonin 60; Belongs to the chaperonin (HSP60) family. (557 aa)
	F0ZG20_DICPU	Uncharacterized protein. (187 aa)
	F0ZGK8_DICPU	Uncharacterized protein. (286 aa)
	F0ZH50_DICPU	Uncharacterized protein; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (207 aa)
	F0ZIA2_DICPU	Uncharacterized protein. (165 aa)
	F0ZIG4_DICPU	NEDD8-activating enzyme E1 regulatory subunit. (526 aa)
	F0ZIL9_DICPU	Profilin; Belongs to the profilin family. (127 aa)
	F0ZJ10_DICPU	PA14 domain-containing protein. (719 aa)
	F0ZJ89_DICPU	Uncharacterized protein. (1353 aa)
	F0ZJB2_DICPU	DIRP domain-containing protein. (845 aa)
	F0ZJT6_DICPU	Uncharacterized protein. (905 aa)
	F0ZJX7_DICPU	Lipoxygenase domain-containing protein. (629 aa)
	F0ZK03_DICPU	Uncharacterized protein. (1346 aa)
	F0ZKD8_DICPU	CBM49 domain-containing protein. (1133 aa)
	F0ZKF7_DICPU	CBM49 domain-containing protein. (1137 aa)
	F0ZKF8_DICPU	CBM49 domain-containing protein. (1119 aa)
	F0ZKF9_DICPU	CBM49 domain-containing protein. (1139 aa)
	F0ZKL9_DICPU	RECA_3 domain-containing protein. (192 aa)
	F0ZKM5_DICPU	Uncharacterized protein. (1340 aa)
	F0ZL61_DICPU	ERCC4 domain-containing protein. (702 aa)
	F0ZLC9_DICPU	Uncharacterized protein. (226 aa)
	F0ZLD8_DICPU	HAP2-GCS1 domain-containing protein. (1733 aa)
	F0ZLW7_DICPU	Uncharacterized protein. (552 aa)
	F0ZM43_DICPU	PA14 domain-containing protein. (741 aa)
	F0ZMA7_DICPU	Uncharacterized protein. (928 aa)
	F0ZMA9_DICPU	Uncharacterized protein. (934 aa)

Your Current Organism:

Dictyostelium purpureum

NCBI taxonomy Id: 5786
Other names: D. purpureum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F0Z7C1_DICPU	F0ZBM3_DICPU	F0Z7C1	F0ZBM3	AAA domain-containing protein; Belongs to the AAA ATPase family.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.515
F0Z7C1_DICPU	F0ZBX6_DICPU	F0Z7C1	F0ZBX6	AAA domain-containing protein; Belongs to the AAA ATPase family.	SAP domain-containing protein.	0.465
F0Z7C1_DICPU	F0ZKL9_DICPU	F0Z7C1	F0ZKL9	AAA domain-containing protein; Belongs to the AAA ATPase family.	RECA_3 domain-containing protein.	0.495
F0Z7C1_DICPU	F0ZN98_DICPU	F0Z7C1	F0ZN98	AAA domain-containing protein; Belongs to the AAA ATPase family.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.647
F0Z7C1_DICPU	F0ZQW1_DICPU	F0Z7C1	F0ZQW1	AAA domain-containing protein; Belongs to the AAA ATPase family.	Protein kinase domain-containing protein.	0.513
F0Z7C1_DICPU	F0ZQX2_DICPU	F0Z7C1	F0ZQX2	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.413
F0Z7C1_DICPU	F0ZRP1_DICPU	F0Z7C1	F0ZRP1	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.665
F0Z7C1_DICPU	F0ZSA5_DICPU	F0Z7C1	F0ZSA5	AAA domain-containing protein; Belongs to the AAA ATPase family.	Peptidase C50 domain-containing protein.	0.518
F0Z7C1_DICPU	F0ZT69_DICPU	F0Z7C1	F0ZT69	AAA domain-containing protein; Belongs to the AAA ATPase family.	RECA_2 domain-containing protein.	0.745
F0Z7C1_DICPU	F0ZUE3_DICPU	F0Z7C1	F0ZUE3	AAA domain-containing protein; Belongs to the AAA ATPase family.	BUB1 N-terminal domain-containing protein.	0.667
F0Z7C1_DICPU	F0ZYI7_DICPU	F0Z7C1	F0ZYI7	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.413
F0Z7E7_DICPU	F0ZMV1_DICPU	F0Z7E7	F0ZMV1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Inositol 5-phosphatase 4.	0.910
F0Z7E7_DICPU	F0ZUR5_DICPU	F0Z7E7	F0ZUR5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.942
F0Z7E7_DICPU	F0ZZM8_DICPU	F0Z7E7	F0ZZM8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.922
F0Z8A7_DICPU	F0Z988_DICPU	F0Z8A7	F0Z988	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.541
F0Z8T7_DICPU	F0Z988_DICPU	F0Z8T7	F0Z988	Cnd1 domain-containing protein.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.666
F0Z8T7_DICPU	F0ZJT6_DICPU	F0Z8T7	F0ZJT6	Cnd1 domain-containing protein.	Uncharacterized protein.	0.999
F0Z988_DICPU	F0Z8A7_DICPU	F0Z988	F0Z8A7	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.541
F0Z988_DICPU	F0Z8T7_DICPU	F0Z988	F0Z8T7	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Cnd1 domain-containing protein.	0.666
F0Z988_DICPU	F0ZB94_DICPU	F0Z988	F0ZB94	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.431