(20 nodes) Response to purine-containing compound network (Dictyostelium purpureum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F0ZY22_DICPU	Rap-GAP domain-containing protein. (896 aa)
	F0ZZM8_DICPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1485 aa)
	F1A0G6_DICPU	Uncharacterized protein. (978 aa)
	F1A0L7_DICPU	Uncharacterized protein; Belongs to the peptidase C1 family. (376 aa)
	F0ZPW7_DICPU	Myosin II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
	F1A3K9_DICPU	Rab-GAP TBC domain-containing protein. (1000 aa)
	F0ZAW2_DICPU	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (976 aa)
	F1A3R7_DICPU	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (850 aa)
	rasC	Uncharacterized protein rasC. (189 aa)
	F0ZAN3_DICPU	Uncharacterized protein. (860 aa)
	rapA	Uncharacterized protein rapA. (188 aa)
	F0ZC59_DICPU	Bulb-type lectin domain-containing protein. (135 aa)
	AcaA	Uncharacterized protein AcaA. (1265 aa)
	ACRA	Uncharacterized protein ACRA. (1893 aa)
	F0ZT81_DICPU	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family. (2305 aa)
	F0ZUZ9_DICPU	Bulb-type lectin domain-containing protein. (201 aa)
	AcgA	Uncharacterized protein AcgA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (881 aa)
	F0Z7E7_DICPU	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1729 aa)
	rasG	Uncharacterized protein rasG. (189 aa)
	Pde4	Phosphodiesterase. (848 aa)

Your Current Organism:

Dictyostelium purpureum

NCBI taxonomy Id: 5786
Other names: D. purpureum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AcaA	AcgA	F1A4L3	F0ZVG7	Uncharacterized protein AcaA.	Uncharacterized protein AcgA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.520
AcaA	Pde4	F1A4L3	F0ZGW8	Uncharacterized protein AcaA.	Phosphodiesterase.	0.517
AcgA	AcaA	F0ZVG7	F1A4L3	Uncharacterized protein AcgA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein AcaA.	0.520
AcgA	Pde4	F0ZVG7	F0ZGW8	Uncharacterized protein AcgA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Phosphodiesterase.	0.525
F0Z7E7_DICPU	F0ZZM8_DICPU	F0Z7E7	F0ZZM8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.922
F0ZAW2_DICPU	F1A3R7_DICPU	F0ZAW2	F1A3R7	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.995
F0ZT81_DICPU	rapA	F0ZT81	F1A4I5	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein rapA.	0.408
F0ZT81_DICPU	rasC	F0ZT81	F1A411	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein rasC.	0.408
F0ZT81_DICPU	rasG	F0ZT81	F0ZWE6	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein rasG.	0.408
F0ZZM8_DICPU	F0Z7E7_DICPU	F0ZZM8	F0Z7E7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.922
F0ZZM8_DICPU	rasC	F0ZZM8	F1A411	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein rasC.	0.439
F0ZZM8_DICPU	rasG	F0ZZM8	F0ZWE6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein rasG.	0.423
F1A3R7_DICPU	F0ZAW2_DICPU	F1A3R7	F0ZAW2	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.995
Pde4	AcaA	F0ZGW8	F1A4L3	Phosphodiesterase.	Uncharacterized protein AcaA.	0.517
Pde4	AcgA	F0ZGW8	F0ZVG7	Phosphodiesterase.	Uncharacterized protein AcgA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.525
rapA	F0ZT81_DICPU	F1A4I5	F0ZT81	Uncharacterized protein rapA.	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	0.408
rasC	F0ZT81_DICPU	F1A411	F0ZT81	Uncharacterized protein rasC.	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	0.408
rasC	F0ZZM8_DICPU	F1A411	F0ZZM8	Uncharacterized protein rasC.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.439
rasG	F0ZT81_DICPU	F0ZWE6	F0ZT81	Uncharacterized protein rasG.	Protein kinase, atypical group; Belongs to the PI3/PI4-kinase family.	0.408
rasG	F0ZZM8_DICPU	F0ZWE6	F0ZZM8	Uncharacterized protein rasG.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.423