61 items (Dictyostelium purpureum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F0ZLS6_DICPU	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (497 aa)
	F0Z7G3_DICPU	Uncharacterized protein. (419 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (449 aa)
	F0ZA46_DICPU	4-hydroxyphenylpyruvate dioxygenase. (373 aa)
	F0ZBR2_DICPU	Uncharacterized protein. (638 aa)
	F0ZBZ1_DICPU	Uncharacterized protein. (231 aa)
	F0ZDH7_DICPU	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (457 aa)
	F0ZDT7_DICPU	DAO domain-containing protein. (346 aa)
	F0ZDY0_DICPU	Dihydrolipoyl dehydrogenase. (490 aa)
	F0ZDZ0_DICPU	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa)
	F0ZE13_DICPU	Lipoyl-binding domain-containing protein. (354 aa)
	F0ZE95_DICPU	NAD+ dependent glutamate dehydrogenase. (1032 aa)
	F0ZFE5_DICPU	Uncharacterized protein. (66 aa)
	F0ZFT6_DICPU	Uncharacterized protein; Belongs to the GST superfamily. (220 aa)
	F0ZG03_DICPU	4-hydroxyphenylpyruvate dioxygenase. (376 aa)
	F0ZI93_DICPU	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (435 aa)
	F0ZII4_DICPU	Aminotran_1_2 domain-containing protein. (417 aa)
	F0ZJ63_DICPU	Methylcrotonyl-CoA carboxylase. (689 aa)
	F0ZJ64_DICPU	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1006 aa)
	F0ZJ65_DICPU	Aminotran_1_2 domain-containing protein. (427 aa)
	F0ZJ93_DICPU	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (556 aa)
	F0ZKU3_DICPU	Lipoyl-binding domain-containing protein. (152 aa)
	F0ZLN9_DICPU	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (330 aa)
	F0ZLP9_DICPU	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (376 aa)
	gadA	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (473 aa)
	F0ZME5_DICPU	Uncharacterized protein. (450 aa)
	F0ZMZ5_DICPU	Mitochondrial isovaleryl-CoA dehydrogenase. (411 aa)
	F0ZNV7_DICPU	Hydroxymethylglutaryl-CoA lyase. (387 aa)
	F0ZP18_DICPU	Uncharacterized protein. (574 aa)
	F0ZP75_DICPU	PALP domain-containing protein. (343 aa)
	F0ZPC1_DICPU	D-aminoacyl-tRNA deacylase. (196 aa)
	F0ZPY2_DICPU	FAD_binding_3 domain-containing protein. (420 aa)
	F0ZRW3_DICPU	Lipoyl-binding domain-containing protein. (148 aa)
	F0ZRW4_DICPU	Lipoyl-binding domain-containing protein. (144 aa)
	F0ZRW5_DICPU	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (151 aa)
	F0ZRW6_DICPU	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (146 aa)
	F0ZS51_DICPU	Cysteine dioxygenase. (232 aa)
	F0ZSP4_DICPU	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (478 aa)
	F0ZTV2_DICPU	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (593 aa)
	GADC	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (459 aa)
	F0ZVU4_DICPU	Uncharacterized protein. (417 aa)
	tdo	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (401 aa)
	F0ZWD8_DICPU	Alanine transaminase. (530 aa)
	F0ZWJ0_DICPU	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (303 aa)
	F0ZWJ2_DICPU	PALP domain-containing protein. (334 aa)
	F0ZYV5_DICPU	Lipoyl-binding domain-containing protein. (171 aa)
	F1A0C8_DICPU	Aspartate aminotransferase. (421 aa)
	F1A0P1_DICPU	D-ser_dehydrat domain-containing protein. (391 aa)
	F1A0U0_DICPU	Uncharacterized protein; Belongs to the arginase family. (299 aa)
	F1A1K3_DICPU	Fumarylacetoacetase. (424 aa)
	F1A1Z5_DICPU	Uncharacterized protein. (460 aa)
	F1A2S8_DICPU	3-hydroxyisobutyrate dehydrogenase. (318 aa)
	F1A3J7_DICPU	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (179 aa)
	F1A3P0_DICPU	Homogentisate 1,2-dioxygenase. (440 aa)
	F1A3U9_DICPU	Uncharacterized protein. (912 aa)
	F1A425_DICPU	Threonine ammonia-lyase. (1097 aa)
	F1A4B3_DICPU	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (404 aa)
	F1A4H7_DICPU	Methylmalonate-semialdehyde dehydrogenase. (520 aa)
	GADB	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (456 aa)
	F1A5G4_DICPU	Fe-ADH domain-containing protein. (543 aa)
	F1A6D2_DICPU	Ornithine aminotransferase. (423 aa)

Your Current Organism:

Dictyostelium purpureum

NCBI taxonomy Id: 5786
Other names: D. purpureum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F0Z7G3_DICPU	F0ZA46_DICPU	F0Z7G3	F0ZA46	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.423
F0Z7G3_DICPU	F0ZDY0_DICPU	F0Z7G3	F0ZDY0	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.536
F0Z7G3_DICPU	F0ZE13_DICPU	F0Z7G3	F0ZE13	Uncharacterized protein.	Lipoyl-binding domain-containing protein.	0.479
F0Z7G3_DICPU	F0ZG03_DICPU	F0Z7G3	F0ZG03	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.423
F0Z7G3_DICPU	F0ZI93_DICPU	F0Z7G3	F0ZI93	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.673
F0Z7G3_DICPU	F0ZJ63_DICPU	F0Z7G3	F0ZJ63	Uncharacterized protein.	Methylcrotonyl-CoA carboxylase.	0.458
F0Z7G3_DICPU	F0ZLN9_DICPU	F0Z7G3	F0ZLN9	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.673
F0Z7G3_DICPU	F0ZLP9_DICPU	F0Z7G3	F0ZLP9	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.673
F0Z7G3_DICPU	F0ZNV7_DICPU	F0Z7G3	F0ZNV7	Uncharacterized protein.	Hydroxymethylglutaryl-CoA lyase.	0.407
F0Z7G3_DICPU	F0ZP18_DICPU	F0Z7G3	F0ZP18	Uncharacterized protein.	Uncharacterized protein.	0.573
F0Z7G3_DICPU	F0ZTV2_DICPU	F0Z7G3	F0ZTV2	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.673
F0Z7G3_DICPU	F0ZVU4_DICPU	F0Z7G3	F0ZVU4	Uncharacterized protein.	Uncharacterized protein.	0.943
F0Z7G3_DICPU	F0ZWJ0_DICPU	F0Z7G3	F0ZWJ0	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.740
F0Z7G3_DICPU	F1A1Z5_DICPU	F0Z7G3	F1A1Z5	Uncharacterized protein.	Uncharacterized protein.	0.423
F0Z7G3_DICPU	F1A4H7_DICPU	F0Z7G3	F1A4H7	Uncharacterized protein.	Methylmalonate-semialdehyde dehydrogenase.	0.615
F0Z7G3_DICPU	F1A5G4_DICPU	F0Z7G3	F1A5G4	Uncharacterized protein.	Fe-ADH domain-containing protein.	0.640
F0ZA46_DICPU	F0Z7G3_DICPU	F0ZA46	F0Z7G3	4-hydroxyphenylpyruvate dioxygenase.	Uncharacterized protein.	0.423
F0ZA46_DICPU	F0ZBR2_DICPU	F0ZA46	F0ZBR2	4-hydroxyphenylpyruvate dioxygenase.	Uncharacterized protein.	0.461
F0ZA46_DICPU	F0ZG03_DICPU	F0ZA46	F0ZG03	4-hydroxyphenylpyruvate dioxygenase.	4-hydroxyphenylpyruvate dioxygenase.	0.902
F0ZA46_DICPU	F0ZI93_DICPU	F0ZA46	F0ZI93	4-hydroxyphenylpyruvate dioxygenase.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.454