STRINGSTRING
ACX72013.1 ACX72013.1 ACX72014.1 ACX72014.1 ACX72015.1 ACX72015.1 ACX72016.1 ACX72016.1 ACX72017.1 ACX72017.1 mtrE mtrE mtrD mtrD mtrC mtrC mtrB mtrB mtrA mtrA mtrF mtrF mtrG mtrG mtrH mtrH ACX72147.1 ACX72147.1 ACX72148.1 ACX72148.1 ACX72301.1 ACX72301.1 ACX72302.1 ACX72302.1 ftr ftr ACX72566.1 ACX72566.1 ACX72568.1 ACX72568.1 ACX72569.1 ACX72569.1 ACX72571.1 ACX72571.1 ACX72572.1 ACX72572.1 ACX72573.1 ACX72573.1 ACX72574.1 ACX72574.1 ACX72575.1 ACX72575.1 ACX72576.1 ACX72576.1 ACX72655.1 ACX72655.1 ACX72657.1 ACX72657.1 ACX72658.1 ACX72658.1 ACX72659.1 ACX72659.1 ACX72660.1 ACX72660.1 ACX72661.1 ACX72661.1 ACX72777.1 ACX72777.1 ACX72809.1 ACX72809.1 ACX73021.1 ACX73021.1 ACX73050.1 ACX73050.1 ACX73051.1 ACX73051.1 ACX73052.1 ACX73052.1 ACX73053.1 ACX73053.1 ACX73322.1 ACX73322.1 ACX73338.1 ACX73338.1 ACX73339.1 ACX73339.1 ACX73340.1 ACX73340.1 ACX73341.1 ACX73341.1 ACX73342.1 ACX73342.1 ACX73343.1 ACX73343.1 ACX73344.1 ACX73344.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACX72013.1KEGG: mja:MJ0842 methyl coenzyme M reductase I, subunit beta (McrB); TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit. (444 aa)
ACX72014.1TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D; KEGG: mja:MJ0843 methyl coenzyme M reductase I, operon protein D (McrD). (162 aa)
ACX72015.1TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C; KEGG: mja:MJ0844 methyl coenzyme M reductase I, operon protein C (McrC). (200 aa)
ACX72016.1KEGG: mfe:Mefer_0937 methyl-coenzyme M reductase, gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. (260 aa)
ACX72017.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (553 aa)
mtrETetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (303 aa)
mtrDTetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (230 aa)
mtrCTetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (266 aa)
mtrBTetrahydromethanopterin S-methyltransferase; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (109 aa)
mtrATetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa)
mtrFTetrahydromethanopterin S-methyltransferase, F subunit; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (68 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (84 aa)
mtrHTetrahydromethanopterin S-methyltransferase, MtrH subunit; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (319 aa)
ACX72147.1KEGG: mja:MJ0863 heterodisulfide reductase, subunit B2 (hdrB2); TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein. (296 aa)
ACX72148.1TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: mja:MJ0864 heterodisulfide reductase, subunit C2 (hdrC2). (186 aa)
ACX72301.1KEGG: mja:MJ0743 heterodisulfide reductase, subunit B1 (hdrB1); TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein. (294 aa)
ACX72302.1TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: mja:MJ0744 heterodisulfide reductase, subunit C (HdrC). (194 aa)
ftrFormylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (301 aa)
ACX72566.1PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: mfe:Mefer_0555 formylmethanofuran dehydrogenase subunit E region. (214 aa)
ACX72568.1PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0005 formate dehydrogenase, beta subunit. (379 aa)
ACX72569.1PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: mja:MJ0006 formate dehydrogenase, alpha subunit. (378 aa)
ACX72571.1KEGG: mja:MJ1194m formylmethanofuran dehydrogenase (tungsten), subunit B, selenocysteine-containing; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: molybdopterin oxidoreductase. (441 aa)
ACX72572.14Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (654 aa)
ACX72573.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1193 polyferredoxin (MvhB). (391 aa)
ACX72574.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mae:Maeo_0097 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (479 aa)
ACX72575.1PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: mae:Maeo_0098 NADH ubiquinone oxidoreductase 20 kDa subunit. (299 aa)
ACX72576.1PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: mae:Maeo_0099 methyl-viologen-reducing hydrogenase delta subunit. (150 aa)
ACX72655.1KEGG: mja:MJ1171 formylmethanofuran dehydrogenase, subunit C (tungsten) (FwdC); TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein. (273 aa)
ACX72657.1TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: mja:MJ1169 formylmethanofuran dehydrogenase, subunit A (tungsten) (FwdA). (567 aa)
ACX72658.1PFAM: molydopterin dinucleotide-binding region; KEGG: mja:MJ1168 formylmethanofuran dehydrogenase, subunit D (tungsten) (FwdD). (133 aa)
ACX72659.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mfe:Mefer_0157 4Fe-4S ferredoxin iron-sulfur binding domain protein. (82 aa)
ACX72660.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1166 formylmethanofuran dehydrogenase, subunit F (tungsten) (FwdF). (356 aa)
ACX72661.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1165 formylmethanofuran dehydrogenase, subunit E (tungsten) (FwdE). (151 aa)
ACX72777.1KEGG: mja:MJ0658 hypothetical protein. (322 aa)
ACX72809.1PFAM: Uncharacterised conserved protein UCP019262; KEGG: mja:MJ0548 hypothetical protein. (293 aa)
ACX73021.1Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: mja:MJ1353m formate dehydrogenase. (677 aa)
ACX73050.1KEGG: mja:MJ0081 methyl coenzyme M reductase II, subunit beta (MrtB); TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit. (442 aa)
ACX73051.1KEGG: mja:MJ0082 methyl coenzyme M reductase II, subunit gamma (MtrG); TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. (266 aa)
ACX73052.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (552 aa)
ACX73053.1TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D; KEGG: mfe:Mefer_0817 methyl-coenzyme M reductase operon protein D. (160 aa)
ACX73322.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1662 methyl coenzyme M reductase system, component A2-like. (550 aa)
ACX73338.14Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (658 aa)
ACX73339.1Contains selenocysteine; PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: mja:MJ1190a coenzyme F420-reducing hydrogenase, delta subunit. (133 aa)
ACX73340.1PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: mja:MJ1191 methylviologen-reducing hydrogenase, gamma chain (VhuG). (288 aa)
ACX73341.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ1192m methylviologen-reducing hydrogenase, alpha subunit. (418 aa)
ACX73342.1KEGG: mja:MJ1192m methylviologen-reducing hydrogenase, alpha subunit; Contains selenocysteine. (50 aa)
ACX73343.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1193 polyferredoxin (MvhB). (391 aa)
ACX73344.1KEGG: mja:MJ1194m formylmethanofuran dehydrogenase (tungsten), subunit B, selenocysteine-containing; Contains selenocysteine; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: molybdopterin oxidoreductase. (435 aa)
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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