STRINGSTRING
pfkA pfkA tal tal eno eno Tlie_0755 Tlie_0755 Tlie_0995 Tlie_0995 pgk pgk tpiA tpiA Tlie_1077 Tlie_1077 pgi pgi Tlie_1281 Tlie_1281 Tlie_1372 Tlie_1372 Tlie_1373 Tlie_1373 Tlie_1382 Tlie_1382
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (440 aa)
Tlie_0755PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterProIPR018209: IPR015793: IPR015794: IPR008279: IPR 001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (602 aa)
Tlie_0995Glyceraldehyde-3-phosphate dehydrogenase (NAD+); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020830: IPR020831: IPR020832: IPR006424: IPR 020828: IPR020829; KEGG: aco:Amico_0834 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, cata [...] (340 aa)
pgkPFAM: Phosphoglycerate kinase; COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911: IPR001576; KEGG: tai:Taci_0890 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (270 aa)
Tlie_1077Fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: tai:Taci_1013 fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase, class II; TIGRFAM: fructose-1,6-bisphosphatase, class II. (331 aa)
pgiPFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672: IPR018189; KEGG: aco:Amico_1366 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family. (452 aa)
Tlie_1281Transketolase domain-containing protein; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0021 Transketolase; InterPro IPR005474: IPR005475: IPR005476; KEGG: aco:Amico_1388 transketolase central region; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase central region. (649 aa)
Tlie_1372Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: aco:Amico_1460 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, C-subunit. (314 aa)
Tlie_1373Transketolase domain-containing protein; PFAM: Transketolase, thiamine diphosphate binding domain; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: aco:Amico_1461 transketolase domain protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase domain protein. (287 aa)
Tlie_1382PFAM: Fructose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: aco:Amico_0571 ketose-bisphosphate aldolase class-II; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase family protein. (428 aa)
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.